M-fasen Flashcards by Ellen Pellen

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Q

När bildas M-cyklin/Cdk?

A

Under G2 men är till en början inaktiv

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Q

Varför är M-cyklin/cdk inaktivt?

A

Wee1 vinner dragkampen mot cdc25

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Q

När är man i M-fasen?

A

När M-cyklin/cdk är aktivt

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Q

Ge exempel på proteiner som gör M-fasen möjlig

A

Aurorakinas och Polokinas

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Q

Vad gör Polokinas?

A

Delar på centrosomerna

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Q

Vad gör aurorakinas?

A

Bidrar till spolkroppsbildningen

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Q

Hur aktiveras APC/C?

A

Med cdc20

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Q

När degraderas sekurin av APC/C?

A

Vid metafasens slut (när ekvatorialplattan är färdig)

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Q

Vad gör aktivt separas?

A

Klyver kohesinringar i centromeren

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Q

När är separas inaktivt?

A

När det är bundet till securin

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Q

När aktiveras CKI?

A

Vid DNA-skada, cellöverväxt…

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