M1 L4 Flashcards
(5 cards)
1
Q
Miller
A
Do mutagens cause different mutations? yes
LacI gene in E.coli
2
Q
pre- mutagenic lesion
A
a change to DNA that may lead to a mutation
3
Q
defects in DNA repair
A
-> neuro degenerative disorders
-> xeroderma pigmentosum (sunlight sensitivity)
4
Q
colibactin
A
-secreted by some human gut E. coli
- mutagen
- associated with colorectal cancer
5
Q
EMS
A
- alkylating agent
- causes G-C to A-T mutations
