M2 Topic 6: Central Nervous System Flashcards

(37 cards)

1
Q

What is the CNS composed of?

A

Brain and spinal cord

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2
Q

What is the main role of the CNS?

A

Receive, integrate, and send information using neurons

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3
Q

What are the two types of matter that make up the CNS?

A
  • Grey matter
  • White matter
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4
Q

Grey matter

A

Cortex (outer layer, cell bodies)

  • Nuclei and cell bodies of neurons
  • Processing area
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5
Q

White matter

A

Subcortex (inner layer, axons)

  • Axons (myelin)
  • Transmission area
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6
Q

What is a sulcus?

A

Grooves in the brain

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7
Q

What is a gyrus?

A

Ridges in the brain

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8
Q

What are the four main structures in the brain?

A
  • Cerebrum
  • Cerebellum
  • Diencephalon
  • Brainstem
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9
Q

Cerebrum

A

Located on outer surface of brain, responsible for thinking, motor/sensory functions, executive functions

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10
Q

Cerebellum

A

Located at back of brain, responsible for balance, motor coordination (e.g. smooth movement)

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11
Q

Diencephalon

A

Located in middle of brain, responsible for relaying sensory information, autonomic & endocrine control

Consists of 4 main parts…

  • Thalamus = relays sensory info to cortex
  • Hypothalamus = controls ANS and hormone secretion
  • Epithalamus = connects emotions to other parts of brain
  • Pineal gland = regulates sleep cycle
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12
Q

Brain stem

A

Located at bottom of brain, responsible for keeping you alive, autonomic functions (e.g. breathing)

3 main parts…

  • Midbrain = eye movement, relay signals for hearing, seeing reflexes
  • Pons - relay station, coordinates control for breathing
  • Medulla = controls involuntary functions, breathing, blood pressure, swallowing, vomiting
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13
Q

The cortex

A

Uppermost part of brain is called cerebrum, outer layer of cerebrum is called the cortex

  • Brain ‘controls’ opposite side of body (with some exceptions)
  • Right brain gets info and sends to left side
  • Complex with visual system
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14
Q

4 main parts (lobes) of the cortex

A
  • Frontal lobe
  • Parietal lobe
  • Temporal lobe
  • Occipital lobe

Named after bones of cranium that overlie them

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15
Q

Frontal lobe

A

Primary motor cortex

  • Motor function, executive functions
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16
Q

Parietal lobe

A

Primary sensory cortex

  • Integration of sensory information
17
Q

Temporal lobe

A

Primary auditory cortex

  • Integration of auditory information, hearing, memory
18
Q

Occipital lobe

A

Primary visual cortex

  • Integration of visual information, sight
19
Q

What protects the CNS and brain tissue?

A
  • Meninges (membranes)
  • Cerebrospinal fluid (CSF)
  • Blood-brain barrier (BBB)
20
Q

Meninges (membranes)

A

3 membranes that surround the brain…

  • Dura matter (hard, outer layer)
  • Arachnoid matter (spider-web like, middle layer)
  • Pia matter (delicate, tender, inner layer
21
Q

Ventricles of the brain

A

Ventricles in the brain is a fluid filled space filled with cerebrospinal fluid

  • Lateral ventricles (1 and 2)
  • 3rd and 4th ventricles extend through brain stem and connect to central canal that runs through spinal cord
22
Q

Cerebrospinal fluid (CSF)

A

Clear, watery fluid that flows in and around brain and spinal cord

  • Cushions and nourishes brain
  • Secreted into ventricles and flows in subarachnoid space
  • Contain modified ependymal cells called the choroid plexus, makes CSF by transporting water, ions, vitamins and nutrients from blood
  • CSF reabsorbed into blood at projections called the arachnoid villi
23
Q

Glial cells (neuroglia/nerve glue) in the CNS

A

Do more than glue neurons, have other important functions

  • Outnumber neurons almost 10 to 1
  • 6 types, 4 in CNS, 2 in PNS
24
Q

Types of glial cells in the CNS

A
  • Astrocytes
  • Microglial cells
  • Oligodendrocytes
  • Ependymal cells
25
Astrocytes
Cling to neurons and 'cover' nearby capillaries, anchors neuron to nutrient supply lines - Shaped like stars
26
Microglial cells
Monitoring neuronal health and migrate toward them if injured
27
Oligodendrocytes
Wrap thicker axons in CNS with insulating myelin sheath
28
Ependymal cells
Line ventricles making permeable barrier between CSF and cells of CNS
29
Blood-brain barrier (BBB)
Highly selective permeability of brain capillaries - Protects brain from toxic water-soluble compounds and other blood-borne problems - Astrocytes 'foot processes' secrete substances that promote tight junctions between endothelial cells - Neurons are protected from harmful substances in blood because brain capillaries are not leaky
30
Endothelial cell
A cell lining a blood vessel
31
Capillary
A very small blood vessel
32
Tract
A bundle of fibres, used for connecting different areas of brain and spinal cord - Tracts between major areas and between hemispheres of brain - Tracts in spinal cord Note: bundle of fibres (axons) in PNS is a nerve, but in CNS is a tract
33
Spinal cord
Extension of the brainstem, where many tracts are Made of 4 main areas... - Cervical (C1-C8) - Thoracic (T1-T12) - Lumbar (L1-L5) - Sacral (S1-S5) - Coccygeal nerve Each area has number of nerve roots associated with individual vertebrae
34
Protection of the spinal cord
Also protected by meninges and CSF - CSF circulates in subarachnoid space (between arachnoid and pia mater)
35
Grey matter in the spinal cord
Consists mainly of cell bodies of neurons associated with somatic sensory nuclei and somatic motor nuclear
36
White matter in the spinal cord
Consists of the fibre tracts going up and down the spinal cord
37
Spinal cord structure
Cervical enlargement - Innervates upper limbs - Between C5 and T1 Lumbosacral enlargement - Innervates lower limbs - Between L1 and S3 Conus medullaris - Terminal end of spinal cord - Between L1 and L2 Filum terminale - Fibrous band to stabilise spinal cord Cauda equina - Bundle of nerve roots located at lower end of spinal cord