Macromolecules Flashcards

1
Q

What are functional groups

A

7 chemical groups that add diversity to carbon skeletons

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2
Q

Hydroxyl

A
-OH
found in alcohols and carbohydrates
can form hydrogen bonds
hydrophilic 
ex is ethanol
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3
Q

Carbonyl

A

-Carbon with double bonded O
within a molecule called ketone
at end of molecule called aldehyde
ex is acetone and formaldehyde

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4
Q

Carboxyl

A

-Carbon double bonded O and an OH
highly polar, gives off a proton in water
found in amino acids
ex is acetic acid

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5
Q

Amino

A
-NH2
very polar group: N attracts a proton H+ in water
in solution it becomes NH3+
found in amino acids
ex is urea
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6
Q

Sulfhydryl

A
-SH
hydrophilic
vital to protein function
polar group
ex is cysteine
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7
Q

Phosphate

A
P bonded to 4 O with one double bond
2 negative charges
very polar
used in nucleotides
ex is ATP
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8
Q

Methyl

A

-CH3
hydrophobic
important for DNA
ex is thymine and uracil

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9
Q

What are the four macromolecules

A

carbohydrates
lipids
proteins
nucleic acids

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10
Q

What is dehydration responsible for

A

synthesis/creation of polymers by removing a water molecule

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11
Q

What is hydrolysis responsible for

A

breakdown of polymers by adding a water molecule

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12
Q

general formula for carbohydrates

A

Cn[H2O]n (n>= 3)

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13
Q

What are carbohydrates

A
sugars
saccharides (mono and di)
usually ends in -ose
carbonyl and hydroxyl
most important is glucose
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14
Q

How are monosaccharides classified

A

number of carbons
location of carbonyl group
handedness (asymmetric C)
there are linear and ring forms for 5- and 6- carbon sugars

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15
Q

ketoses v. aldoses

A

ketoses have carbonyl group inside while aldoses have carbonyl group at the end

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16
Q

what are disaccharides

A

two sugars that are covalently joined at a glycosidic bond/linkage like maltose(GG), sucrose (GF), and lactose (GGal)

17
Q

how do disaccharides form

A

through dehydration - removing water molecules

18
Q

What are polysaccharides used for

A

storage like alpa glucose to store energy and structural like beta glucose for cellulose

19
Q

What are lipids

A

not true polymers
large parts of hydrocarbons
very hydrophobic
fats, phospholipids, steroids

20
Q

Describe phospholipids

A

polar molecules that make the membrane of a cell, has a hydrophilic head and a hydrophobic tail, with 2 fatty acids connected at the glycerol

21
Q

Examples of steroids

A

cholesterol, estradiol, testosterone

4 fused rings with different functional groups that have a planar structure

22
Q

What are polypeptides

A

Proteins, polymers of amino acids

23
Q

What makes a peptide

A

amino group, carboxyl group, H, and a R chain group

24
Q

What is the alpha carbon

A

the asymmetric carbon

25
Q

What is a peptide bond

A

where to amino acids join by dehydration between the OH of carboxyl and H of amino group

26
Q

What are the two ends of a polypeptide

A
Amino End (N-terminus)
Carboxyl End (C-terminus)
27
Q

How are amino acids structured

A

primary structure: the amino acid sequence
secondary structure: beta pleated sheets of alpha helices with h bonding
tertiary structure: interaction of R’s by h-bonds, ionic bonds, disulfide bridges, and hydryphobic interactions

28
Q

quaternary structure

A

multiple protein subunits interlocked togethers

29
Q

What are nucleic acids

A

storage of information

gene expression