Magnesium Flashcards Preview

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Flashcards in Magnesium Deck (37):
1

over 60% of mg in the body is located in the____
25% is located in the___

bones
muscle

2

sources

nuts seeds, legumes, whole grains, corn, carrots, black strap molasses, dairy, chocolate, cocoa, tea, coffee

3

magnesium is absorbed in the ____

small intestine (primarily in the distal jejunum and ileum)

4

magnesium can be absorbed by ___ pathways

2

5

a saturable carrier mediated active traansporter helps absorb magnesium when intake is ___, this route is stimulated by____

low
vitamin D

6

passive diffusion helps absorb magnesium when intake is___

highe

7

factors that enhance magnesium absorption

vitamin d
simple sugars

8

factors that inhibit magnesium absorption

phytates
fiber
excesive unabsorbed fatty acids
minerals- Ca and K

9

magnesium is transported in the blood in what three forms

free ionized
bound to protein
complexed with other ions

10

PTH _____ plasma concentration of Mg

increases

11

how does PTH increase plasma concentrations of Mg

increases intestinal absorption
decreases renal excretion
enhances bone resorption

12

functions of magnesium

energy production
structural role
ion transport across membranes
cell signalling

13

magnesium participates as a cofactor in all aspects of energy metabolism including

glycolysis
beta-oxidation
TCA cycle

14

____exists primarily as a complex with Mg

ATP

15

60% of the magnesium in the body is associated with ___ and ___ as part of the bone crystal matrix

calcium
phosphorous

16

magnesium is required for the active transport of ions including ____ and ____ across cell membranes

potassium
calcium

17

magnesium affects the conduction of

nerve impulses
muscle contraction
blood vessel dilation
normal heart rhythm

18

cell signaling requires Mg-ATP for the phosphorylation of proeins and the formation of the cell signaling molecule _____

cAMP

19

cAMP is involved in the secretion of ___ from the parathyroid gland

PTH

20

Mg is excreted primarily in the

urine and feces

21

True or False, magnesium cannot be lost in perspiration

False

22

conditions increase the risk of magnesium deficiency

malabsorption syndromes
renal disorders
chronic alcoholism
elderly

23

S&S of deficiency

hypomagnesemia
hypocalcemia, hypokalemia
retention of Na
low PTH
mm tremor, spasm, cramps, tetany
chest tightness, SOB
palp and cardiac arrhyth
loss of appetite, n/v
anxiety, panic, depression, fatigue, insomnia

24

clinical indications for Mg supplementation

hypertension
migraine headaches

25

_____ is a relatively common dose-related side effect of Mg supplementation

diarrhea

26

individuals with _____ are at higher risk for adverse effects from excess supplemental mg intake

renal impairment

27

hypermagnesemia results in_____

hypotension

28

severe hypermagnesemia may result in _____

cardiac arrest

29

CI of Mg

hypermagenesemia
end stage renal dz
myasthenia gravis
UTI
* caution with hyperparathyroidsism

30

high ___ intake may decrease tissue levels of mg

calcium

31

magnesium is needed for ____ secretion

PTH

32

high levels of ____ inhibit release of PTH

Mg

33

hydroxylation of _____ in the liver requires Mg

Vit D

34

magnesium is essential for the cellular uptake of ___ from the blood

potassium

35

high doses of ____ in supplemental form interfere with the absorption of mg

zinc

36

____ increases the cellular uptake of MG

vitamin b6

37

large doses of ____ may increase the need for magnesium

thiamine