Flashcards in Malignant bone tumours Deck (14):
1
what group of people do osteosarcomas occur in
young adults 60% are under 25
older patients have predisposing factors
M>F
2
what is produced in osteosarcoma
malignant osteoclasts form osteoid
3
where does osteosarcoma occur
at the end of long bones
4
what does osteosarcoma present like
grows out of bone, raising bony capsule - runs over the surface
erodes and destroys bony cortex and extends into soft tissue
5
codmans triangle
raised triangle on x-ray
6
what are the variants of osteosarcoma
osteoblastic, chordoblastic, fibroblastic
7
what are the investigations for osteosarcoma and the treatment
biopsy, CT for mets
pre op chemo
surgical resection
post op chemo
8
large and slow to metastasis
chondrosarcoma
9
malignant nodules - finger like processes infiltrate lamellar bone obliterating marrow - separation of nodules by fibrous bands
chondrosarcoma
10
exhibits pure hyaline differentiation
chondrosarcoma
11
Who does ewings sarcoma occur in
10-20s
12
malignant primary bone tumour of the endothelial cells of the marrow
ewings sarcoma
13
what is the presentation of ewings sarcoma
great mimic - hot swollen tender joint w raised inflame markers
14