Management of hypertension Flashcards

(38 cards)

1
Q

in most patients with hypertension, what is the target blood pressure to aim for?

A

140/90mmHg and if tolerated 130/80mmHg or lower in most patines

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2
Q

in people over age of 65 and diabetes, what is the target blood pressure to aim fo?

A

= 140-130mmHg but NOT < 120mmHg

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3
Q

in very old people, what is the target blood pressure to aim for?

A

= 140-130mmHg but NOT< 130mmHg

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4
Q

when should alcohol reduction be recommended for prevention & treatment of hypertension?

A

amongst heavy drinkers

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5
Q

for every kilogram of weight lost, how much does this Lower the blood pressure?

A

1mmHg is lots for every kg

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6
Q

if you have a no salt added diet, how does this reduce blood pressure?

A

reduces BP by 2-4mmHg

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7
Q

reduction in what ion may also reduce long term risk of CV events?

A

long term sodium reduction

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8
Q

what activity reduces blood pressure 3.8/2.6mmHg?

A

aerobic exercise

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9
Q

what is the relationship between proportional risk reduction and absolute level of risk factor?

A

proportional risk reduction is INDEPENDENT of the absolute level of the risk factor

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10
Q

true or false.

everybody is hypertensive & dyslipidaemic.

A

True

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11
Q

what is the main benefit of anti-hypertensive therapies due to?

A

due to BP lowering

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12
Q

name 5 generic BP drugs?

A

1) thiazide diuretics
2) ACE inhibitors/ARBs
3) calcium channel blockers
4) beta blockers
5) spironolactone, alpha blockers, centrally acting, older drugs

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13
Q

what are 5 targeted BP drugs?

A

1) B blockers (Ca blockers) in angina
2) ACEI & B blockers in CCF
3) ACEI/ARBs in diabetic nephropathy
4) Alpha blockers in prostatism
5) thiazide in elderly
6) others

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14
Q

in people under age of 55 what is the first step treatment should they be given?

A

A
= ACE inhibitor
OR
= low cost angiotensin II receptor blocker (ARB)

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15
Q

in people over age of 55 or black person of African or Caribbean family origin what is the first step should be given?

A

C

= calcium channel blockers (CCB)

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16
Q

what is the step 2 in treatment for hypersensitive patients?

A

A + C
= ACE inhibitor or low cost angiotensin II receptor blockers
AND
= calcium channel blocker

17
Q

what is step 3 in treatment.for hypersensitive patients?

A
A + C + D 
= ACE inhibitor or low cost angiotensin II receptor blockers 
AND 
= calcium channel blocker 
AND 
= thiazide like diuretics
18
Q

what is step 4 also known as?

A

resistant hypertension

19
Q

what needs to be done in steps 4?

A
= ACE inhibitor or low cost angiotensin II receptor blockers 
AND 
= calcium channel blocker 
AND 
= thiazide like diuretics 

+ further diuretic or alpha or beta blocker

20
Q

what is one of the main consequences of using a diuretic?

A

low potassium levels = hyperkalaemia

21
Q

if diuretics still need to be used, what should also be given to avoid potassium levels getting to 4.5mmol/l lower?

A

= low dose spironolactone (25mg once daily)

22
Q

if at step 4, further diuretics are not tolerated, what could be used?

A

an alpha or beta blocker.

23
Q

how many more times effective is adding a drug than titrating?

A

5x more effective

24
Q

true or false.

Starting with two drugs is always better than starting with one.

25
True or false. | Combination therapy has fewer side effects than mono-therapy.
true.
26
what are 7 things associated with resistant hypertension?
1) non-concordance 2) white coat effect 3) pseudo-hypertension 4) lifestyle factors 5) drug interactions 6) secondary hypertension 7) true resistance
27
what drug is most effective at treating resistant hypertension?
= spironolactone
28
when should patients only be defined as resistant hypertension?
unless their BP remains uncontrolled on spironolactone.
29
what 2 groups of people should take spironolactone with caution?
1) diabetes | 2) low GFR
30
in summary what drugs are available for people under 55?
``` - ACE/ARB or - B-blocker if fertile female - calcium antagonista - diuretic - spironolactone ```
31
inn summary what drugs are available for people over 55?
- calcium antagonists - ACE/ARB - diuretics - spironolactone
32
what are the 6 examples of hypertensive drugs that could be used?
1) diuretics 2) calcium channel blockers 3) angiotensin receptor antagonnists 4) alpha adrenoceptor antagonistts 5) beta adrenoceptor antagonists 6) ACE inhibitor
33
give an example of a thiazide diuretic. | and the side effects of them.
Example = bendrofluazide Side effects = hypokalaemia = hyperglycaemia = hyperuricaemia
34
give an example of beta adrenoceptor antagonist. | and the side effects of them.
Example; = atenolol Side effects; = donut use in asthma = tired, cold peripheries
35
give an example of calcium channel blockers. | and the side effects of them.
Example; = amiodipine Side effects; = ankleoedema
36
give an example of an alpha adrenoceptor antagonist. | and the side effects of them.
Example; = doxazosin or prazosin Side effects; = postural hypotension
37
give an example of an ACE inhibitor. | and the side effects of them.
Example; = lisinnopril Side effects; = large decreases in BP hypertensive patients. = hypotension in patients treated. DON'T GIVE IN PREGNANNCY
38
give an example of an angiotensin receptor antagonist. | and the side effects of the.
example ; = losartan Side effects; = DON'T GIVE IN PREGNANCY - bilateral renal artery stenosis