Mass Spectrometer Flashcards by Khristine Tapado

Mass spectrometers are used to determine which of the following?
a) Composition in sample
b) Concentration of elements in sample
c) Relative mass of atoms
d) Properties of sample

c) Relative mass of atoms

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Who invented mass spectrometers?
a) J.J Thompson
b) Goldstein
c) Nikola Tesla
d) Aston

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In mass spectrometer, the ions are sorted out in which of the following ways?
a) By accelerating them through electric field
b) By accelerating them through magnetic field
c) By accelerating them through electric and magnetic field
d) By applying a high voltage

c) By accelerating them through electric and magnetic field

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In mass spectrometer, the sample that has to be
analysed is bombarded with which of the following?
a) Protons
b) Electrons
c) Neutrons
d) Alpha particles

b) Electrons

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Mass spectrometer separates ions on the basis of which of the following?
a) Mass
b) Charge
c) Molecular weight
d) Mass to charge ratio

d) Mass to charge ratio

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No two molecules will be fragmented and ionized in
exactly the same manner.
a) True
b) False

a) True

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The procedure for mass spectroscopy starts with which of the following processes?
a) The sample is bombarded by electron beam
b) The ions are separated by passing them into electric and magnetic field
c) The sample is converted into gaseous state
d) The ions are detected

c) The sample is converted into gaseous state

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In a mass spectrometer, the ion currents are measured using which of the following?
a) Scintillation counter
b) Ion counter
c) Electrometer tube
d) Electric fields

c) Electrometer tube

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Which of the following ions pass through the slit and
reach the collecting plate?
a) Negative ions of all masses
b) Positive ions of all masses
c) Negative ions of specific mass
d) Positive ions of specific mass

d) Positive ions of specific mass

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In mass spectrometer, the sample gas is introduced into the highly evacuated spectrometer tube and it is ionised by electron beam.
a) True
b) False

a) True

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Which of the following statements is not true about
mass spectrometry?
a) Impurities of masses different from the one being
analysed interferes with the result
b) It has great sensitivity
c) It is suitable for data storage
d) It is suitable for library retrieval

a) Impurities of masses different from the one being
analysed interferes with the result

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Which of the following is not a component of mass
spectrometer?
a) Inlet system
b) Sweep generator
c) Ion transducer
d) Mass analyser

b) Sweep generator

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Inlet system is also known as which of the following?
a) Initial system
b) Sample reservoir
c) Sample handling system
d) Element injection system

c) Sample handling system

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Which of the following can be introduced into the
ionization chamber directly?
a) Solid samples with low vapour pressure
b) Solid samples with high vapour pressure
c) Liquid samples with low density
d) Liquid samples with high density

a) Solid samples with low vapour pressure

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Which of the following is normally done to convert the
sample into the gaseous state?
a) Sample is pressurized
b) Chemical reactions are made to occur
c) Sample is heated
d) Sample is cooled

c) Sample is heated

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Which of the following probes are used for the
introduction of the sample?
a) Silica
b) Quartz
c) Graphite
d) Silver

a) Silica

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Which of the following is not a type of ionisation?
a) Field ionisation
b) Spontaneous ionisation
c) Spark ionisation
d) Chemical ionisation

b) Spontaneous ionisation

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Mass analyser is similar to which of the following in
optical spectrometer?
a) Source
b) Monochromator
c) Detector
d) Sample

b) Monochromator

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Which of the following is not one of the types of mass analyser?
a) Magnetic sector analyser
b) Frequency sweep analyser
c) Double focussing spectrometer
d) Time of flight analyser

b) Frequency sweep analyser

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Which of the following is not a type of ion detector used in mass spectrometers?
a) Electron multiplier
b) Flame emission detector
c) Faraday cup collector
d) Photographic plates

b) Flame emission detector

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Under which of the following temperatures is the
ionisation chamber maintained?
a) 100oC
b) 200oC
c) 300oC
d) 400oC

c) 300oC

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Which of the following is used to inject liquid samples?
a) Hypodermic needle
b) Glass bulb
c) Capillary tube
d) Curvette

a) Hypodermic needle

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Which of the following is not a characteristic of
nebulizers that are commonly used?
a) Low cost
b) Low uptake rate
c) High efficiency
d) High uptake rate

d) High uptake rate

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In glow discharge ion source, the sample is atomised by which of the following process?
a) Evaporation
b) Sputtering
c) Heating
d) Annealing

b) Sputtering

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1. Which of the following produces the electron beam in magnetic deflection mass spectrometer? a) Tungsten filament b) Quartz rod c) Silica d) Rhodium filament

a) Tungsten filament

2. In magnetic deflection mass spectrometer, in which of the following ways is acceleration applied to the direction of motion? a) In random manner b) Parallel to it c) Perpendicular to it d) Along it

c) Perpendicular to it

4. Which of the following separate the ions according to their mass-to-charge? a) Ion source b) Detector c) Magnetic sector d) Electric sector

c) Magnetic sector

7. The electric sector field is not subject to hysteresis. a) True b) False

a) True

3. Direct focussing is obtained by deflecting the ion beam along a _________ trajectory through the magnetic field. a) 120o b) 150o c) 190o d) 180o

d) 180o

5. Mattauch-Herzog geometry involves a deflection of which of the following radians in a radial electrostatic field analyser? a) √2Π b) Π/2 c) Π/3√4 d) Π/4√2

6. Which of the following leads to the limitation of resolution? a) All ions do not have same energy b) All ions do not have same charge c) All ions are not of the same size d) All ions do not have the same charge

d) All ions do not have the same charge

8. Which of the following components need to be added in order to increase the resolution? a) Ion source b) Detector c) Magnetic sector d) Electric sector

a) Ion source

9. Which of the following is commonly varied in magnetic deflection mass spectrometer? a) Electric sector b) Magnetic fold strength c) Magnetic constant d) Electric constant

b) Magnetic fold strength

10. Nier-Johnson geometry involves a deflection of which of the following radians in a radial electrostatic field analyser? a) Π b) Π/2 c) Π/3 d) Π/4

b) Π/2

11. An accuracy of 1 part in 102 has been obtained in precision mass measurements. a) True b) False

b) False

1. Which of the following is not a component of the time of flight analyser spectrometer? a) Ion source b) Field free separation region c) Electron multiplication region d) Photo tube

a) Ion source

3. Which of the following is not an advantage of mass spectrometer? a) Simple b) Rugged c) High sensitivity d) Unlimited mass range

c) High sensitivity

4. All the ions entering the tube have the same kinetic energy. a) True b) False

a) True

5. If all the ions have the same kinetic energy how are their masses related to their velocities? a) Mass and velocity are equal b) Mass and velocity are not related c) Mass and velocity are directly proportional d) Mass and velocity are inversely proportional

d) Mass and velocity are inversely proportional

6. Which of the following is true about time of flight analyser spectrometers? a) Lighter particles arrive at the detector earlier b) Heavier particle arrive at the detector earlier c) Lighter and heavier particles arrive together at the detector d) Lighter particles do not reach the detector

a) Lighter particles arrive at the detector earlier

7. In the time of flight mass spectrometer, ions are formed by which of the following methods? a) Pulsed ionization method b) Acceleration method c) Dynamic method d) Ion excitation method

a) Pulsed ionization method

8. The evacuated tube is also known as which of the following? a) Pulse tube b) Detector tube c) Drift tube d) Acceleration tube

c) Drift tube

9. The current produced by ions arriving at the collector necessitates the use of which of the following? a) Wide band amplifier b) Narrow band amplifier c) Wide band filter d) Narrow band filter

a) Wide band amplifier

10. Which of the following is an ion optic device in which ions pass through a mirror and their flight is reversed? a) Reversal device b) Reflectron c) Mirror arrangement d) Separation chamber

b) Reflectron

11. Which of the following statements about mass spectrometers are not true? a) Time of flight mass spectrometer has the ability to record the entire mass spectrum at a time b) Time of flight mass spectrometers have poor resolution c) Conventional spectrometer detects only one peak at a time d) All spectrometers have the ability to record the entire mass spectrum at a time

d) All spectrometers have the ability to record the entire mass spectrum at a time

1. Which of the following is placed just before the detector in a radiofrequency mass spectrometer? a) Ion source b) Potential energy selector c) Ionisation chamber d) Reflectron

b) Potential energy selector

1. Which of the following is placed just before the detector in a radiofrequency mass spectrometer? a) Ion source b) Potential energy selector c) Ionisation chamber d) Reflectron

c) Ionisation chamber

3. The alternating voltage rf voltage is applied to which of the following? a) All grids b) Central grid c) Alternate grids d) None of the grids

b) Central grid

4. The rf spectrometer contains a magnet. a) True b) False

b) False

5. The DC ion accelerating voltage is swept from _________ a) 0 to 50 V b) 50 to 100 V c) 200 to 300 V d) 50 to 250 V

d) 50 to 250 V

7. In Bennet spectrometer, the rf voltage has a fixed frequency. a) True b) False

a) True

6. The resolution of the Bennet tube can be improved by using which of the following? a) Sine wave rf signal b) Square wave rf signal c) Triangular wave rf signal d) Random signal

b) Square wave rf signal

8. The spurious lines can be reduced to a minimum by using which of the following? a) Single stage tube b) Two stage tube c) Three stage tube d) Reflectron

c) Three stage tube

10. Which of the following is not the feature of Bennet type spectrometer? a) Lightweight b) Simple c) Absence of spurious lines d) Moderate resolution

c) Absence of spurious lines

9. Which of the following is the disadvantage of using three stage tubes? a) Reduced resolution b) Bulky construction c) Complex d) Heavy

a) Reduced resolution

1. Which of the following is not a feature of quadrupole mass spectrometer? a) Low cost b) Light weight c) Low speed electronic scanning d) Simple in construction

c) Low speed electronic scanning

2. Which of the following is not a component of quadrupole mass filter? a) Electrodes b) Choke c) DC potential d) Detector

d) Detector

11. The resolving power of Bennet type spectrometer is primarily based on which of the following? a) Distance between detector and reflectron b) Difference between the individual rf accelerating stages c) Length of the drift tube d) Laser beam used

b) Difference between the individual rf accelerating stages

3. The mass selection scheme uses a dc potential and not a radio frequency potential. a) True b) False

b) False

4. If to one pair of electrodes one potential with one sign is applied, which of the following is applied to the other pair of electrodes? a) Same potential with same sign b) Different potential with same sign c) Different potential with different sign d) Same potential with different sign

d) Same potential with different sign

5. Which of the following is the heart of quadrupole instrument? a) Electrodes b) Choke c) DC potential d) Detector

a) Electrodes

7. Which of the following does not affect the resolution of the instrument? a) Changing length of electrode b) Changing slope of scan line c) Quality of machining of the rods d) Changing length of drift tube

d) Changing length of drift tube

6. Which of the following has to be done to increase the resolution of the quadrupole mass spectrometer? a) Increasing distance between detector and reflectron b) Increasing difference between the individual rf accelerating stages c) Increasing the length of the drift tube d) Increasing the rod length of the electrode

d) Increasing the rod length of the electrode

8. In cases where differentiation is required between very similar substances, which of the following techniques making use of quadrupole principle is preferred? a) Evaporation mass spectrometry b) Pyrolysis mass spectrometry c) Plasma mass spectrometry d) Trapped ion mass spectrometry

b) Pyrolysis mass spectrometry

10. Which of the following is used to cool the ion source? a) Liquid sodium shield c c) Water d) Freon

a) Curie point

9. In pyrolysis spectrometry, heating is done until which of the following is reached? a) Curie point b) Boiling point c) Until production of superheated vapour d) Until 100oC

a) Curie point

11. In quadrupole mass spectrometer, the ratio u/v is mass dependent, where ‘u’ is the DC voltage and ‘v’ is the peak amplitude. a) True b) False

b) False

12. When a value of q is kept constant, the value of m/e is proportional to which of the following when ‘m’ is the mass number, ‘e’ is the electric charge, ‘u’ is the DC potential, ‘v’ is the peak amplitude and ‘f’ is the frequency? a) u/v ratio b) u c) v d) f

c) v

1. Which of the following is not an ion transducer or detector? a) Faraday cup collector b) Channeltron c) Micro-channel plate d) Flame ionization detector

d) Flame ionization detector

2. Which of the following is similar to photo multiplier transducer? a) Faraday cup collector b) Channeltron c) Micro-channel plate d) Electron multiplier transducer

d) Electron multiplier transducer

3. Which of the following is used in places where ion currents are very low? a) Faraday cup collector b) Channeltron c) Micro-channel plate d) Electron multiplier transducer

d) Electron multiplier transducer

4. Discrete type electron multiplier transducers can provide current gain upto which of the following? a) 10^2 b) 10^5 c) 10^7 d) 10^11

c) 10^7

5. Continuous dynode electron multiplier transducer is a trumpet shaped device made with which of the following? a) Glass doped with lead b) Steel doped with bronze c) Phosphor bronze doped with iron d) Iron doped with calcium

a) Glass doped with lead

6. The potential maintained across the continuous dynode multiplier transducer is which of the following? a) 1 to 5kV b) 5 to 10kV c) 2.5 to 6.2kV d) 1.8 to 2kV

d) 1.8 to 2kV

8. Which of the following are true about dynodes used in discrete dynode electron multiplier? b) Successive dynodes are held at lower potential c) Successive dynodes are held at higher potential d) All dynodes are held at very low potential

c) Successive dynodes are held at higher potential

10. Which of the following is the least sensitive ion detector? a) Faraday cup collector b) Channeltron c) Micro-channel plate d) Electron multiplier transducer

a) Faraday cup collector

7. Which of the following are not the characteristics of an electron multiplier transducer? a) Rugged b) Reliable c) Microsecond of response time required d) High current gain

c) Microsecond of response time required

9. In which of the following detectors, the collector is placed in an inclined manner? a) Faraday cup collector b) Channeltron c) Micro-channel plate d) Electron multiplier transducer

a) Faraday cup collector

13. Photographic plates have greater sensitivity and resolution than electron multipliers. a) True b) False

a) True

11. Photographic plates are coated with which of the following? a) Lead b) Quartz c) Silver bromide d) Mercuric sulphate

c) Silver bromide

12. Which of the following detectors are well suited for spark source instruments? a) Faraday cup collector b) Photographic plates c) Micro-channel plate d) Electron multiplier transducer

b) Photographic plates

14. Which of the following detectors consist of an array of glass capillaries? a) Faraday cup collector b) Photographic plates c) Micro-channel plate d) Electron multiplier transducer

c) Micro-channel plate

15. Which of the following detectors can be used for ions with short life time? a) Faraday cup collector b) Photographic plates c) Micro-channel plate d) Electron multiplier transducer

b) Photographic plates

1. ICP’s principle is similar to which of the following? a) Flame emission spectroscopy b) Fourier transforms spectroscopy c) Atomic emission spectroscopy d) Absorption spectroscopy

c) Atomic emission spectroscopy

2. ICP is used to analyse samples in which of the following states? a) Solids b) Liquids c) Gases d) Solids and liquids

d) Solids and liquids

3. Solid samples are introduced into the ICP spectrometer using which of the following? a) Nebulizer b) Curvette having glass windows c) Probe d) Laser ablation system

d) Laser ablation system

4. Liquid samples are introduced into the ICP spectrometer using which of the following? a) Nebulizer b) Curvette having glass windows c) Probe d) Laser ablation system

a) Nebulize

5. Atomisation or ionisation occurs at which of the following conditions? a) Vacuum pressure b) Atmospheric pressure c) Low pressure d) High pressure

d) High pressure

6. Ions flow is pumped into the vacuum system using which of the following? a) Orifice b) Nozzle c) Venturi meter d) Dall tube View Answer

a) Orifice

7. Which of the following is not the characteristic of ICP spectrometer? a) Easy sample introduction b) It can trace multiple elements c) High detection limits d) Accurate

c) High detection limits

8. ICP spectrometer is a sequential multi-element analyser that has scan times less than ____ for one sweep. a) 10ms b) 20ms c) 50ms d) 100ms

b) 20ms

9. Double focussing section analysers offer better resolution than ICP spectrometry system. a) True b) False

a) True

10. The most common type of ion detector found in ICP system is which of the following? a) Faraday cup collector b) Channeltron c) Micro-channel plate d) Flame ionization detector

b) Channeltron

11. Which of the following is the most accurate method of determination of elemental composition? a) Spectroscopy b) Isotope dilution c) Isobar dilution d) Chromatography

b) Isotope dilution

12. Which of the following is the disadvantage of ICP mass spectroscopy? a) Incapable of multi-element analysis b) Less sensitivity c) Impossible to obtain isotopic information d) Not useful for detection of non-metals

d) Not useful for detection of non-metals

13. The isobaric interference is not caused in which of the following elements? a) Argon b) Oxygen c) Helium d) Nitrogen

c) Helium

1. Which of the following is the most sensitive of the spectral methods? a) Absorption spectroscopy b) Mass spectroscopy c) Flame emission spectroscopy d) Atomic emission spectroscopy

b) Mass spectroscopy

2. Which of the following is the disadvantage of gas chromatography? a) It is not a good method b) It cannot be used for qualitative analysis c) It cannot be used for the separation of volatile components d) It does not provide direct identification

d) It does not provide direct identification

3. Cold tray is provided for liquid N2 or CO2 but is used only for extremely small samples. a) True b) False

a) True

4. Which of the following is most often used in the chromatograph in gas chromatograph MS? a) Curvette b) Paper support c) Capillary tube d) Flask

c) Capillary tube

5. GC- MS has been developed for which of the following systems? a) Packed column b) Open tubular column c) Capillary column d) Porous layer column

a) Packed column

6. Which of the following problems occur when combining gas chromatography and mass spectroscopy? a) Difference in operating pressures b) Reduction in sensitivity c) Direct identification is not possible d) It does not permit direct introduction of the effluent

a) Difference in operating pressures

7. The carrier gas with low molecular weight would diffuse at a higher rate than the higher molecular weight sample. a) True b) False

a) True

8. Which of the following is the type of separator used in commercial GC-MS systems? a) Jet type molecular separator b) Porous tube c) Teflon tube d) Flow type separator

a) Jet type molecular separator

9. The system for measurement of ion intensity in GS-MS system consists of which of the following? a) Electrometer b) Ion meter c) Ion transducer d) Intensity meter

a) Electrometer

10. The system for measurement of ion intensity in GS-MS system consists of which of the following? a) Band pass amplifier b) Narrow band amplifier c) Wide band amplifier d) Low pass amplifier

c) Wide band amplifier

1. Introduction of total HPLC effluent into MS is feasible. a) True b) False

b) False

2. The gas burden from conventional LC flow rates creates nearly _____ times more gas than cryo-pumped vacuum system can handle. a) 5 b) 10 c) 20 d) 40

c) 20

3. Which of the following should be in a position to split the effluent? a) Interface b) Ion source c) Makeup gas d) Microbore

a) Interface

4. Which of the following is the most commonly used interface? a) Nebulizer b) Chopper c) Filter d) Vapourising chamber

a) Nebulizer

5. Only ______ percent of the effluent of the liquid chromatography must be introduced in the mass spectrometer. a) 1-2 % b) 1-5 % c) 1-20 % d) 1-15%

b) 1-5 %

6. Which of the following is the normal nebuliser temperature used in LC mass spectrometry? a) 50-100oC b) 100-200oC c) 125-150oC d) 150-200oC

c) 125-150oC

7. The ions are focussed and de-clustered through which of the following regions? a) Dry helium region b) Wet oxygen region c) Wet chlorine region d) Dry nitrogen region

d) Dry nitrogen region

8. The ions are passed into the high vacuum analyser through which of the following? a) Orifice b) Nozzle c) Nebulizer d) Venturi tube

a) Orifice

9. Using an interface would reduce detection limit and sensitivity. a) True b) False

a) True

10. Gas burden from conventional LC flow rates is which of the following? a) 1ml/min of water produces 1.2 l/mm of gas b) 1ml/min of water produces 2.4 l/mm of gas c) 2ml/min of water produces 3.2 l/mm of gas d) 1ml/min of water produces 4.2 l/mm of gas

a) 1ml/min of water produces 1.2 l/mm of gas

1. Tandem mass spectroscopy combines which of the following devices? a) Mass spectrometer and gas-solid chromatograph b) Mass spectrometer and gas-liquid chromatograph c) Mass spectrometer and gas chromatograph d) Mass spectrometer and mass spectrometer

d) Mass spectrometer and mass spectrometer

2. In tandem spectroscopy, the first stage sepatation device is a mass spectrometer. a) True b) False

a) True

3. Which of the following is used to separate a single mass that is characteristic of a given analyte in a mixture? a) First mass spectrometer b) Second mass spectrometer c) Filter d) Precursor

a) First mass spectrometer

4. The mass-selected ions are activated in which of the following ways that cause them to fall apart to produce product ions? a) Collisional activation b) Evaporational activation c) Inert gas activation d) Thermal activation

a) Collisional activation

5. The final MS/MS spectrum consists only of product ions from the selected precursor. a) True b) False

a) True

6. In reverse-geometry mass spectrometer which of the following precedes the electric sector? a) Nebulizer b) Orifice c) Magnetic sector d) Mass spectrometer

c) Magnetic sector

7. A magnetic sector alone can be used as a mass spectrometer, with roughly _____ resolution. a) Low b) High c) Unit d) Infinite

c) Unit

8. What does the acronym ‘MIKES’ stand for? a) Mass-analysed ion kinetic energy spectrometer b) Mass-based induced kinetic energy spectrometer c) Mass invasive kinetic electric spectrometer d) Mass-analyser in a kinetic energy-type spectrometer

a) Mass-analysed ion kinetic energy spectrometer

9. In MIKES experiments which of the following are measured? a) Product ions b) Product ion kinetic energies c) Product ions mass to charge ratio d) Product ions masses

b) Product ion kinetic energies

10. All ions with the same number of charges will have __________ a) Same kinetic energy b) Different kinetic energies c) Same mass d) Different mass

a) Same kinetic energy

11. A tandem mass spectrometer has which of the following analysers? a) Time of flight mass analyser b) Magnetic deflection analyser c) Radiofrequency analyser d) Quadrupole analyser

a) Time of flight mass analyser

12. Which of the following filters are used in tandem spectrometer? a) Quadrupole mass filter b) Low energy filter c) High energy filter d) Time of flight mass filter

a) Quadrupole mass filter

13. B/E scan is which of the following scans? a) Product ion scan b) Precursor ion scan c) Mass scan d) Charge scan

a) Product ion scan

14. Which of the following is located in the region between two analysers? a) Nebuliser b) Collision cell c) Filter d) Vacuum chamber

b) Collision cell

Mass Spectrometer Flashcards

(131 cards)