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Flashcards in Mechanism of Learning/Memory Deck (51)
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1

these are good for study because we can select random mutations and study effects on behavior

drosophila

2

these are good to be used because they are similar anatomy to humans and are used to study explicit memory

mice

3

aplysia reflexive withdrawal of gill following stimulation of siphone

implicit memory

4

learning to ignore a repeated stimulus

habituation

5

repeated stimulation of siphon results in reduction of epsp in interneuron and motor neuron, and reduced withdrawal of the gills lasting minutes

short term habituation

6

continued stimulation of siphone results in habituation of gill reflex lasting weeks

long term habituation

7

decrease in the number of synaptic contacts between sensory and motor neurons requires blank

protein synthesis

8

decreasing the number of synaptic contacts is called blank and is in long term habituation

pruning,

9

repeated exposure to harmful stimulus causes heightened response/enhancement of reflex

sensitization

10

in sensitization, a blank neuron stimulated by a tail shock releases blank onto presynaptic terminal

facilitator, serotonin

11

serotonin causes an increase in blank which activates blank

cAMP, PKA

12

closing K channels too soon causes blank

prolonged depolarization

13

increase glutamate from sensory cell

heterosynaptic facilitation

14

learning to associate one type of stimulus with another

classical conditioning

15

converting short term memory to long term

consolidation

16

consolidation involves changes in gene expression and blank

protein synthesis

17

high cAMP leads to prolonged activation of blank which activates blank transciption facotr which codes for blank

PKA, CREB, gene expression

18

short term memory storage has a change in the amount of nt release from blank, alter blank influx, and change in opening/closing of blank

presynaptic cell, calcium, K+ channels

19

long term memory storage changes the number of blank which leads to gene expression and blank which takes a while to occur

synapses, protein synthesis

20

gene products generated during long term storage can only be used where

at that specific synapse

21

mutation of fruit flies that is a defective cAMP phosphodiesterase

dunce mutation

22

mutation that is defective Ca dependent adenylate cyclase

rutabaga mutation

23

cAMP pathway is very important for blank

learning/memory

24

used for studies of implicit learned motor behavior, and can easily record from neural circuits

aplysia

25

short term habituation is due to blank of synaptic vesicles

depletion

26

long term habituation is due to blank

synaptic pruning

27

sensitization in short term memory is due to cAMP, PKA signaling where blank increases

nt release

28

long term sensitization is characterized by increased blank

number of synapses

29

main explicit memory circuit

hippocampus

30

donald hebb said that explicit learning occurs if a synapse is strengthened every time presynaptic and postsynaptic activity is blank

correlated