Med Emerg Pharmacology Flashcards

(191 cards)

1
Q

DIAZEPAM Brand Name

A

Valium

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2
Q

DIAZEPAM Class

A

Benzodiazepine

Sedative Hypnotic

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3
Q

DIAZEPAM MOA (3)

A

Inhibits neurotransmitters
Raises seizure threshold
Induces amnesia and sedation

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4
Q

DIAZEPAM Indications (4)

A

Status seizure
Acute anxiety

analgesia for medical procedure (fx reduction/cardioversion)

delirium tremens

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5
Q

DIAZEPAM Contras (6)

A
Allergy
Glaucoma
Coma
Shock
Substance abuse
head injury
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6
Q

DIAZEPAM Adult Seizure Dose

A

5-10mg IV q 10-15prn

–>5mg over 5mins

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7
Q

DIAZEPAM Adult Seizure Max Dose

A

30mg

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8
Q

DIAZEPAM Cardioversion Sedation Adult Dose

A

5-15mg IV over 5-10mins prior to cardioversion

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9
Q

DIAZEPAM Considerations (3)

A

Pregnancy D
Short duration of anti convulsant effect
Reduce dose by 1/2 in elderly

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10
Q

LORAZEPAM Brand Name

A

Ativan

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11
Q

LORAZEPAM Class

A

Benzodiazepine

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12
Q

LORAZEPAM MOA (3)

A

Anxiolytic

Anticonvulsant/sedative

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13
Q

LORAZEPAM Indications (3)

A

Status epilepticus
Severe anxiety
Sedation

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14
Q

LORAZEPAM Contras (3)

A

Coma
Shock
Suspected drug use

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15
Q

LORAZEPAM Side Effects (3)

A

Hypotension
Resp depression
Bradycardia

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16
Q

LORAZEPAM Adult Dose

A

0.5-2mg IV IN IM q PRN

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17
Q

LORAZEPAM Max Adult Dose

A

8mg (school)

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18
Q

LORAZEPAM Administration note

A

When given IV/IO must dilute with equal volume of NS. Dilution unnecessary with IM administration.

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19
Q

LORAZEPAM Considerations (3)

A

Pregnancy D

Inadvertent arterial admin may cause vasospasm and gangrene

Expires in 6 weeks if not refrigerated

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20
Q

MIDAZOLAM Brand Name

A

Versed

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21
Q

MIDAZOLAM Class

A

Benzodiazepine

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22
Q

MIDAZOLAM MOA (3)

A

Anxiolytic
Sedative
Memory impairment

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23
Q

MIDAZOLAM Indications (4)

A

Status seizure
Sedation
Anxiolytic prior to RSI
Conscious sedation

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24
Q

MIDAZOLAM Contras (7)

A
Glaucoma
Shock
Coma
EtOH
OD pt
Depressed vitals

Use of other CNS depressants, barbiturates, EtOH, narcotics

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25
MIDAZOLAM Seizure dose
2.5-5mg slow IVP IV IM IO IN
26
MIDAZOLAM Considerations (3)
Pregnancy D Give immediately prior to intubation attempt Requires constant resp/cardiac fxn monitoring
27
ACETAMINOPHEN Brand Name
Tylenol
28
ACETAMINOPHEN Class
Analgesic | AntiPyretic
29
ACETAMINOPHEN MOA
Reduces prostaglandins | Acts on the brain to decrease body T
30
ACETAMINOPHEN Indications (2)
fever | px
31
ACETAMINOPHEN Contras (2)
Allergy | Severe liver disease
32
ACETAMINOPHEN Adult Dose
20mg/kg PO
33
ACETAMINOPHEN Toxic dose
150mg/kg
34
ACETAMINOPHEN Consideration
Avoid in pt's with severe liver disease
35
ETOMIDATE Brand Name
Amidate
36
ETOMIDATE Class
Non barbituate hypnotic
37
ETOMIDATE MOA
Short acting hypnotic that acts on reticular activation system
38
ETOMIDATE Indication
Prep for RSI
39
ETOMIDATE Contras (3)
Allergy Labor/Delivery Septic shock
40
ETOMIDATE Adult Dose
0.1-0.3mg/kg IV over 15-30sec
41
ETOMIDATE Considerations
Pregnancy C | Caution with risk to pregnant women and babies
42
KETAMINE Brand Name
Ketalar
43
KETAMINE Class
sedative/dissociative analgesic
44
KETAMINE MOA
Blocks px receptors and minimizes spinal cord activity
45
KETAMINE Indications (3)
Excited delirium Px RSI Sedation
46
KETAMINE Contras (2)
Allergy | HTN that could be dangerous to pt cdxn
47
KETAMINE Interactions
increases effect of opiates, barbiturates, and nondepolarizing neuromuscular blockers
48
KETAMINE Adult Excited Delirium Dose-
5-10mg/kg IM
49
KETAMINE Adult Px Dose- IV
0.3-0.5MG/KG repeat 1x in 10mins
50
KETAMINE Adult Px Dose- IN/IM
1mg/kg repeat 1x in 20mins
51
KETAMINE RSI Adult Dose- IV
1-2mg/kg IVP q 30-45mins
52
KETAMINE RSI Adult Dose- IM
4-5mg
53
KETAMINE Sedation Adult Infusion Dose
0.5-2mg/kg/hr
54
KETAMINE Sedation Infusion Prep
1000mg Ketamine in 250mL NS --> 4mg/mL
55
KETAMINE Considerations (2)
Pregnancy C | Caution in elderly
56
KETOROLAC Brand Name
Toradol
57
KETOROLAC Class
NSAID
58
KETOROLAC MOA
Inhibits prostaglandin synthesis
59
KETOROLAC Indications (2)
Moderate to Severe Px | Kidney stone px
60
KETOROLAC Contras (5)
``` Allergy ASA allergy Bleeding disorders Renal failure Active ulcer ```
61
KETOROLAC Adult Dose IM Kidney Stones
30mg
62
KETOROLAC Adult Dose IV Kidney Stones
15mg
63
KETOROLAC Dose considerations
give 1/2 dose in elderly | pregnancy C
64
ROCURONIUM Brand Name
Zemuron
65
ROCURONIUM Class
NonDepolarizing Neuromuscular blocker
66
ROCURONIUM MOA
Binds to acetylcholine receptor at neuromuscular junction and doesn't initiate depolarization at muscle membrane -->complete muscle relaxation
67
ROCURONIUM Indication
RSI
68
ROCURONIUM Contas (3)
Allergy to bromides | caution with Muscular dystrophy diseases
69
ROCURONIUM Interaction
positive chronotropic drugs may potentiate tachycardia
70
ROCURONIUM Adult Dose
0.6-1.2mg/kg IV
71
ROCURONIUM Considerations (4)
Pregnancy C Doesn't have effect on px or consciousness Will not stop seizures HR and CO will be increased
72
SUCCINYLCHOLINE Brand Name
Anectine
73
SUCCINYLCHOLINE Class
Neuromuscular blocker, depolarizing
74
SUCCINYLCHOLINE MOA
Ultra short acting depolarizing muscle relaxant that binds with cholinergic receptors on the motor end plate
75
SUCCINYLCHOLINE Indication
RSI
76
SUCCINYLCHOLINE Contras (5)
``` penetrating eye injury malignant hyperthermia hyperK acute injury after multisystem trauma major burns ```
77
SUCCINYLCHOLINE Interactions (2)
Potentiated by oxytocin, beta blockers, organophosphates. Diazepam may reduce duration of action
78
SUCCINYLCHOLINE Adult dose
1.5mg/kg IV
79
SUCCINYLCHOLINE Consideration
Pregnancy C
80
AMIODARONE INFUSION MIX
150mg in 100mL NS/D5W
81
EPI INFUSION MIX
1mg 1:1000 in 250mL (4mcg/mL)
82
KETAMINE INFUSION MIX
1000mg in 250mL NS (4mg/mL)
83
LABETALOL INFUSION MIX
200mg in 500mL D5W
84
LIDOCAINE INFUSION MIX
1g in 250mL D5W (4mg/mL)
85
MAG SULFATE INFUSION MIX
2g in 100mL NS/D5W
86
NITRO INFUSION MIX
50mg in 250ml D5W
87
NOREPI INFUSION MIX
4mg in 250mL D5W
88
PROCAINAMIDE INFUSION MIX
2g in 250mL NS (8mg/mL)
89
TXA INFUSION MIX
1g in 100mL NS over 10 mins
90
Activated Charcoal Class
Adsorbant
91
Activated Charcoal MOA
Adsorbs toxins from GI tract
92
Activated Charcoal Indications
Oral poisonings | Medication ODs
93
Activated Charcoal Contras
Comatose pt Corrosive ingestion Caustic ingestion Petroleum ingestion
94
Activated Charcoal Adult Dose
1-2g/kg PO or NGT
95
Activated Charcoal Consideration
Does not adsorb cyanide, lithium, iron, lead, arsenic
96
Dextrose Class
Carb/Hypertonic Solution
97
Dextrose MOA
Rapidly increases serum glucose
98
Dextrose Indications
ALOC secondary to hypoglycemia
99
Dextrose Contraindications
Intracranial bleed | DTs
100
Dextrose Drug Interactions
Bicarb | Coumadin
101
Dextrose Adult Dose
12.5-25g slow IVP repeat as needed
102
Dextrose Considerdation
Do not give to CVA pt unless hypoglycemia documented
103
Glucagon Class
Pancreatic hormone
104
Glucagon MOA
Increases blood glucose by stimulating glycolysis Stabilizes cardiac rhythm during Beta Blocker OD Minimal positive inotrope and chronotrope
105
Glucagon Indications
ALOC with hypoglycemia | Inotropic agent in beta blocker OD
106
Glucagon Contraindications
hyperglycemia | allergy/hypersensitivity
107
Glucagon Adult Dose
0.5-1mg IM/SC/slow IVP q 20mins as needed
108
Glucagon Considerations
Pregnancy C | Ineffective if glycogen stores depleted
109
Glucose Class
Hyperglycemic
110
Glucose MOA
Quickly absorbed glucose to increase blood glucose levels
111
Glucose Indications
Conscious pt's with hypoglycemia
112
Glucose Contraindications
Decreased LOC | N/V
113
Glucose Adult Dose
1 tube, 17-25g
114
Naloxone Brand Name
Narcan
115
Naloxone Class
Narcotic antagonist
116
Naloxone MOA
Competitive inhibition at narcotic receptor sites Reverses respiratory depression secondary Inhibits effects of morphine
117
Naloxone Indications
Respiratory depression secondary to opiate OD Complete/partial reversal of CNS depressants induced by opioids -morphine, heroin, hydromorphone, methadone, demerol, paregoric, fentanyl, oxycodone, codeine, darvon
118
Naloxone Contraindications
Caution with narcotic dependent pt's | Caution with neonates of narcotic addicted moms
119
Naloxone Adult Dose
0.4-2mg (4mg protocols) IV/IM/SC/IN q 5mins
120
Naloxone Max Cumulative dose
10mg (school) no max dose with protocols
121
Naloxone Infusion
2mg in 500mL D5W (4mcg/ml) | infuse at 0.4mg/hr
122
Naloxone Considerations (4)
Pregnancy B Seizures possible May not reverse hypotension Watch for combative behavior with addicts
123
Ondansetron Brand Name
Zofran
124
Ondansetron Class
Antiemetic
125
Ondansetron MOA
Selective 5 HT receptor antagonist | blocks serotonin
126
Ondansetron Indication
N/V
127
Ondansetron Contraindications
Allergy
128
Ondansetron Considerations
Prolongs QT | Pregnancy B
129
Ondansetron Adult dose
4-8mg IV/SL
130
Oxygen Class
Atmospheric gas
131
Oxygen MOA
Reverses hypoxemia
132
Oxygen Indications
``` Hypoxemia Ischemic chest px Respiratory insufficiency Carbon monoxide poisoning ALOC ```
133
Oxygen Contraindication
Hyperventilation | Some COPD pts
134
Thiamine Brand name
Vitamin B1
135
Thiamine MOA
Combines with ATP to form thiamine coenzyme, which is needed for carbohydrate metabolism
136
Thiamine Indications
DTs | Wernicke encephalopathy
137
Thiamine Contraindication
None
138
Thiamine Adult Dose
100mg slow IVP/IM
139
Thiamine Considerations
Pregnancy A Large doses may cause respiratory difficulties Anaphylaxis sometimes reported
140
Glucagon dose Beta Blocker
3-5mg slow IVP/IN/IM | ---> works because it is a positive chronotrope/inotrope
141
Midazolam RSI dose
2.5-10mg IV IO over 2 mins
142
Midazolam Chem Restraint
2.5-5mg over 2 mins q PRN IM IV IN
143
Famotidine Classification
H2 blocker, antihistamine
144
Famotidine MOA
blocks H2 receptors and histamine
145
Famotidine Indication
allergic rxn and anaphylaxis
146
Famotidine Contraindication
allergy
147
Famotidine Adult dose
20mg IV IO
148
Acetaminophen Onset/Duration
20-30mins | 4-6h
149
ASA Onset/Duration
30-60m | 4-6h
150
Activated Charcoal Onset/Duration
Immediate | 24h
151
Adenosine Onset/Duration
Immediate | 10sec
152
Albuterol Onset/Duration
5m | 3-4h
153
Amiodarone Onset/Duration
15m | 40 day half life
154
Atropine Onset/Duration
2-5min | 20m
155
Calcium Onset/Duration
5-15m | up to 4h
156
Dexamethasone Onset/Duration
4-8h | 24-72h
157
Dextrose/D50/D25 Onset/Duration
30-60s | variable
158
Diazepam IV Onset/Duration
1-5m | 15-60m
159
Diazepam IM Onset/Duration
15-30m | 15-60m
160
Diltiazem Onset/Duration
2-10m | 1-3h
161
Epi IV Onset/Duration
Immediate | 3-5m
162
Epi IM/SQ Onset/Duration
5-10m | 20m
163
Etomidate Onset/Duration
15-20s | 5-10m
164
Famotidine Onset/Duration
20m | 4h
165
Fentanyl Onset/Duration
1-2m | 7-15m IM
166
Furosemide Onset/Duration
5 for preload reduction, 30 for diuresis 2h
167
Glucagon Onset/Duration
rapid
168
Heparin Onset/Duration
Immediate | 1.5h
169
Ipatropium Onset/Duration
15-30m | 5-7h
170
Ketamine IV Onset/Duration
30s | 5-10m
171
Ketamine IM Onset/Duration
3-4m | 12-25m
172
Ketorolac IM Onset/Duration
45-60m | 4-6h
173
Labetalol Onset/Duration
5m | duration dose dependent
174
Lidocaine Onset/Duration
45-90s | 10-20m
175
Lorazepam Onset/Duration IV and IM
1-5m IV/15-30m IM | 12-24h
176
Magnesium Onset/Duration
1-5m | 30m
177
Methylprednisolone Onset/Duration
20m-2h | 18-36h
178
Metoprolol Onset/Duration
Immediate | 5-8h
179
Midazolam Onset/Duration
1-3m IV/IO 10-20m IM duration dose dependent
180
Morphine Onset/Duration
IV immediate IM 5-10m duration 2-7h
181
Naloxone Onset/Duration
IV IO immediate IM 5-10m IN 2-3m duration 20-30m
182
Nitro Onset/Duration
Immediate | 30m
183
Ondansetron Onset/Duration
Immediate | 30m-4h
184
Oxytocin IV Onset/Duration
1m | 30m
185
Oxytocin IM Onset/Duration
3-7m | 60m
186
Procainamide Onset/Duration
10-30m | 3-6h
187
Rocuronium Onset/Duration
60-70s | 20m
188
Sodium Bicarb Onset/Duration
Immediate | 1-2h
189
Succinylcholine Onset/Duration
1m | 4-6m
190
Thiamine Onset/Duration
2h | 8h half life
191
TXA Onset/Duration
4h | 48h