Med List #8: Diabetes and Cholesterol

Question 1

Hypertriglyceridemia

Answer 1

omega-3 fatty acids, fenofibrate

Question 2

Hyperlipidemia

Answer 2

atorvastatin, rosuvastatin, ezetimibe

Question 3

Diabetes

Answer 3

insulin lispro, insulin glargine, metformin, dapagliflozin, liraglutide

Question 4

omega-3 fatty acids: Brand Names

Answer 4

Lovaza

Question 5

omega-3 fatty acids: Common Strengths

Answer 5

1g

Question 6

omega-3 fatty acids: Common Frequency

Answer 6

4g QD, 2g BID

Question 7

omega-3 fatty acids: Indications/Use

Answer 7

• Hypertriglyceridemia
• Dietary supplement

Question 8

omega-3 fatty acids: Counseling Tips and Important Info

Answer 8

• Burping and taste disturbances
• Swallow whole, do not open
• Refrigerate to reduce taste and smell

Question 9

fenofibrate: Brand Name

Answer 9

Trillipix, Tricor

Question 10

fenofibrate: Common Strengths

Answer 10

45mg, 48mg, 138mg, 145mg

Question 11

fenofibrate: Common Frequency

Answer 11

QD

Question 12

fenofibrate: Indications/Use

Answer 12

Hypertriglyceridemia

Question 13

fenofibrate: Counseling Tips and Important Info

Answer 13

• Increased liver enzymes
• Discontinue if gallstones form
• Photosensitivity

Question 14

atorvastatin: Brand Name

Answer 14

Lipitor

Question 15

atorvastatin: Common Strengths

Answer 15

10mg, 20mg, 40mg, 80mg

Question 16

atorvastatin: Common Frequency

Answer 16

QD

Question 17

atorvastatin: Indications/Use

Answer 17

• Hyperlipidemia (Reduce LDL cholesterol, reduce triglycerides, increase HDL cholesterol)
• Cardiovascular disease prevention

Question 18

atorvastatin: Counseling Tips and Important Info

Answer 18

• Increased liver enzymes
• Report unusual muscle pain, tenderness, weakness, or dark urine - rhabdomyolysis
• Avoid grapefruit juice (increased drug concentration)
• Contraindicated in pregnancy
• Diarrhea

Question 19

rosuvastatin: Brand Names

Answer 19

Crestor

Question 20

rosuvastatin: Common Strengths

Answer 20

5mg, 10mg, 20mg, 40mg

Question 21

rosuvastatin: Common Frequency

Answer 21

QD

Question 22

rosuvastatin: Indications/Use

Answer 22

• Hyperlipidemia (Reduce LDL cholesterol, reduce triglycerides, increase HDL cholesterol)
• Cardiovascular disease prevention

Question 23

rosuvastatin: Counseling Tips and Important Info

Answer 23

• Increased liver enzymes
• Report unusual muscle pain, tenderness, weakness, or dark urine - rhabdomyolysis
• Avoid grapefruit juice (increased drug concentration)
• Contraindicated in pregnancy
• Diarrhea

Question 24

ezetimibe: Brand Name

Answer 24

Zetia

Question 25

ezetimibe: Common Strengths

Answer 25

10mg

Question 26

ezetimibe: Common Frequency

Answer 26

QD

Question 27

ezetimibe: Indications/Use

Answer 27

Hyperlipidemia

Question 28

ezetimibe: Counseling Tips and Important Info

Answer 28

- Increased liver enzymes - Diarrhea

Question 29

insulin lispro (rapid-acting): Brand Name

Answer 29

Humalog

Question 30

insulin lispro (rapid-acting): Common Strengths

Answer 30

100 units/mL

Question 31

insulin lispro (rapid-acting): Common Frequency

Answer 31

Individualized dosing - Inject 15 min before or immediately after meals

Question 32

insulin lispro (rapid-acting): Indications/Use

Answer 32

- Type 1 Diabetes - Type 2 Diabetes

Question 33

insulin lispro (rapid-acting): Counseling Tips and Important Info

Answer 33

- Low blood sugar (sweating, nausea, dizziness) - Refrigerate unopened vials - Discard after 28 days if at room temperature - Let syringe reach room temp prior to injection to avoid painful injection - Rotate injection sites

Question 34

insulin glargine (long-acting): Brand Name

Answer 34

Lantus

Question 35

insulin glargine (long-acting): Common Strengths

Answer 35

100 units/ml

Question 36

insulin glargine (long-acting): Common Frequency

Answer 36

Individualized dosing - QD

Question 37

insulin glargine (long-acting): Indications/Use

Answer 37

- Type 1 Diabetes - Type 2 Diabetes

Question 38

insulin glargine (long-acting): Counseling Tips and Important Info

Answer 38

- Low blood sugar (sweating, nausea, dizziness) - Refrigerate unopened vials - Discard after 28 days if at room temperature - Let syringe reach room temp prior to injection to avoid painful injection - Rotate injection sites

Question 39

metformin: Brand Name

Answer 39

Glucophage

Question 40

metformin: Common Strengths

Answer 40

500mg, 850mg, 1000mg

Question 41

metformin: Common Frequency

Answer 41

BID or TID MAX: 2550 mg/day

Question 42

metformin: Indications/Use

Answer 42

- Type 2 Diabetes - Polycystic Ovary Syndrome - Weight loss

Question 43

metformin: Counseling Tips and Important Info

Answer 43

- Diarrhea, nausea, abdominal pain - Take w/ food - Titrate dose up weekly (to reduce stomach upset, diarrhea) - Long-term use can cause Vitamin B-12 deficiency

Question 44

dapagliflozin: Brand Name

Answer 44

Farxiga

Question 45

dapagliflozin: Common Strengths

Answer 45

5mg, 10mg

Question 46

dapagliflozin: Common Frequency

Answer 46

QD

Question 47

dapagliflozin: Indications/Use

Answer 47

- Type 2 Diabetes - Chronic kidney disease - Heart failure w/ reduced ejection fraction

Question 48

dapagliflozin: Counseling Tips and Important Info

Answer 48

- Urinary tract infection - Increased urine output - Decreased blood pressure

Question 49

liraglutide: Brand Name

Answer 49

Victoza, Saxenda

Question 50

liraglutide: Common Strengths

Answer 50

18mg/3ml

Question 51

liraglutide: Common Frequency

Answer 51

0.6mg daily for 1 week, titrated up weekly to 1.8mg daily for diabetes, 3 mg daily for weight management

Question 52

liraglutide: Indications/Use

Answer 52

- Type 2 Diabetes - Weight management

Question 53

liraglutide: Counseling Tips and Important Info

Answer 53

- Low blood sugar (sweating, nausea, dizziness) - Rotate injection sites - Diarrhea - Nausea - Headache