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Flashcards in Medical Problems in Pregnancy Deck (59)
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1

What happens to the risk of transmission of toxoplasmosis and CMV infections as pregnancy progresses?

Increases

2

What happens to the consequences of infection with toxoplasmosis and CMV as pregnancy progresses?

They become less severe

3

Parvovirus infection in pregnancy only causes foetal complications before what gestation?

20 weeks

4

Rubella infection in pregnancy only causes foetal complications before what gestation?

16 weeks

5

Herpes infection is most likely to cause foetal complications if primary infection takes place when?

Third trimester

6

Infection with toxoplasmosis, especially within the first 10 weeks of pregnancy, is most associated with what complication?

Miscarriage

7

Is there an increased risk of miscarriage with varicella-zoster infection in pregnancy?

No

8

What is the most significant foetal complication of maternal parvovirus infection?

Hydrops foetalis

9

Maternal rubella infection in pregnancy causes the child to develop which type of hearing loss?

Sensorineural

10

Hepatosplenomegaly is most likely to be a foetal feature of which TORCH infection in pregnancy?

CMV

11

Screening for which infections in pregnancy should be carried out after ultrasound detection of congenital anomalies and severe growth restriction?

TORCH infections

12

Women who are known to be HIV positive undergo what monitoring in pregnancy?

Viral load and CD4 count at least once every trimester

13

A positive test for which type of antibody is diagnostic for recent infection with a TORCH organism?

IgM

14

What pattern of IgG serology would confirm the acute disease with a TORCH organism?

Increasing titre

15

What investigations can be used to determine if there is foetal infection with a TORCH organism after the mother has tested positive?

Amniocentesis for PCR or culture

16

What investigation is required to screen for complications of TORCH organisms in foetuses with proven infection?

Serial ultrasound scans

17

In women with pre-existing HIV on anti-retroviral therapy, should this therapy be continued in pregnancy?

Yes

18

In women with pre-existing HIV not on anti-retroviral therapy, when should this be started in pregnancy?

By 24 weeks

19

How should pregnant women with HIV and a viral load of < 50 RNA copies/ml at 36 weeks gestation be delivered of their babies?

Vaginal delivery

20

How should pregnant women with HIV and a viral load of > 50 RNA copies/ml at 36 weeks gestation be delivered of their babies?

C-section

21

Is breastfeeding advised in women with HIV?

No

22

What medication is used to suppress lactation post-natally in women with HIV?

Cabergoline

23

Anti-virals can be used when in pregnancy for women with hepatitis B and a high viral load?

Third trimester

24

Is there any safe drug treatment for hepatitis C in pregnancy?

No

25

Does the mode of delivery affect the transmission of hepatitis?

No

26

Is breastfeeding advised for women with hepatitis?

Yes

27

What additional medication do babies born to hepatitis B positive mothers receive within 12 hours of delivery?

Hepatitis B vaccine and a dose of hepatitis B immunoglobulin

28

After a baby born to a hepatitis B positive mother has received the first dose of hepatitis B vaccine at delivery, when should the other doses be given?

At 1 and 6 months of age

29

How are women with a primary infection of herpes simplex in pregnancy treated?

Aciclovir from 36 weeks

30

How are women with a recurrence of herpes simplex in pregnancy treated?

No treatment is required