Meeran Book MSK Flashcards
(28 cards)
What is the management of rheumatoid arthritis?
- DMARDs
- Methotrexate
- Sulfasalazine
- Corticosteroid
- Adjunct
- NSAIDs
- Adjunct
Which joints are usually spared at the onset of Rheumatoid arthritis?
DIPs
What are the skin changes in dermatomyositis?
- Heliotrope rash
- Shawl rash
- Macular
- Gottron’s papules
- Mechanics hands
What is the management of osteoarthritis?
- Topical analgesia (+ paracetamol if unsuccessful)
- Capsaicin
- Diclofenac
- Intra-articular methylprednisolone
What are the empirical antibiotics used for septic arthritis?
- Flucloxacillin
- Gentamycin
- Benzylpenicillin
More specific antibiotics are then used once blood cultures have been obtained
Which organisms pre-dispose to Reactive Arthritis?
- Campylobacter
- Yersinia
- Shigella
- Salmonella
- Chlamydia
- Ureaplasma
What is the management of Reactive Arthritis?
- NSAIDs
- Corticosteroids
Which conditions are associated with pseudogout?
- Hypothyroidism
- Hyperparathyroidism
- Wilson’s disease
- Haemochromatosis
- Acromegaly
What is the management of ankylosing spondylitis?
- NSAIDs and back physiotherapy
- Intra-articular steroid injections if needed
How does retinal detachment present?
- Floaters
- Flashing lights
- Rapid loss of vision
What is the pathophysiology of polymyositis?
Inflammation of striated muscle leading to muscle weakness, without pain
Thought to be autoimmune
What is the etiology of SLE?
- 9x more common in women
- More common in Afro-Caribbean patients
- 20-40 years old
What is discoid lupus?
Lupus only characterised by skin changes
What is the most specific antibody for SLE?
Anti-ds DNA
What are anti-centromere antibodies associated with?
Limited cutaneous systemic sclerosis
What is the pulmonary side effect of methotrexate?
Pulmonary fibrosis
What is the triad of anti-phospholipid syndrome?
- Recurrent miscarriages
- Anti-cardiolipin antibodies
- Thrombosis
What are anti-histone antibodies associated with?
Drug induced lupus
What is secondary sjorgen’s syndrome?
Sjorgen’s syndrome on the background of established autoimmune condition
What is the managment of Raynaud’s disease?
- Conservative
- CCBs
- ACEi/ ARBs
What is microstomia?
Beak like nose and small mouth, occasionally seen in limited and diffuse cutaneous systemic sclerosis
Where is skin involvement limited to in limited cutaneous systemic sclerosis?
- Face
- Hands
- Feet
What is Still’s disease?
Juvenile idiopathic arthritis, characterised by swining fevers, a rash and arthritis in those under 16
What is the management of acute gout?
- NSAIDs
- Colchicine (if NSAIDs contraindicated)
