Melanoma Flashcards

(32 cards)

1
Q

Where are most melanomas?

A

Cutaneous

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2
Q

High risk sites for melanoma

A

BANS: Back, Arms, Neck, Scalp

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3
Q

Clinical features of melanoma

A

ABCDE’s: Asymmetry, Border irregularity, Color variation, Diameter greater than 6 mm, Evolving (enlarging/changing color)

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4
Q

What direction is radial growth

A

Lateral

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5
Q

What direction is vertical growth

A

Extends deeper into the connective tissue

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6
Q

Precursor to melanoma

A

Lentigo maligna

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7
Q

4 types of melanoma

A
  1. Lentigo maligna melanoma
  2. Superficial spreading melanoma
  3. Nodular melanoma
  4. Acral lentiginous melanoma
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8
Q

Also called “Hutchinson’s freckle”

A

Lentigo maligna

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9
Q

Lentigo maligna is melanoma in a purely ____ growth phase

A

Radial

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10
Q

Lentigo maligna is a large ____ lesion with ____ borders and ____ pigmentation

A

Macular, irregular, uneven

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11
Q

What signals the vertical growth phase and lentigo maligna melanoma?

A

Nodularity in a previously flat lentigo maligna

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12
Q

Most common type of melanoma

A

Superficial spreading melanoma

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13
Q

Superficial spreading melanoma can be found in the ____ area of men and the __________ of women

A

Interscapular, back of the legs

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14
Q

What does superficial spreading melanoma begin as?

A

A macule or plaque

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15
Q

Histology of superficial spreading melanoma: clusters of atypical _____ along the ____ layer

A

Melanocytes, basal

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16
Q

Nodular melanoma has almost an immediate ____ phase, little if any ____ growth

A

Vertical, radial

17
Q

Most common form of oral melanoma

A

Acral lentiginous melanoma

18
Q

Most common form of melanoma in persons of color

A

Acral lentiginous melanoma

19
Q

Which form of melanoma is more aggressive than cutaneous melanoma?

A

Acral lentiginous melanoma

20
Q

Locations of Acral lentiginous melanoma

A

Palms, Soles, Subungual, Mucous membranes

21
Q

Oral Acral lentiginous melanoma can be ___

22
Q

Acral lentiginous melanoma is typically in ____

23
Q

High risk sites for Acral lentiginous melanoma

A

Hard palate/maxillary alveolar mucosa

24
Q

Where does oral Acral lentiginous melanoma usually metastasize

A

Cervical lymph node

25
What does oral Acral lentiginous melanoma appear as on a radiograph
Irregular radiolucency or mixed lesion
26
Surgical excision of ____ cm margin for cutaneous lesions of melanoma
1-2 cm
27
Prognosis is better if < ____ mm and worse if > ____ mm
Better if < 0.75 mm and worse if > 3.6 mm
28
Which sex has a better prognosis for melanoma? What age?
Females under 50
29
Which cutaneous lesions have the worst prognosis?
Trunk, H&N
30
Which area has a worse prognosis than cutaneous?
Mucosal
31
In general, melanoma has a ___ prognosis
Poor
32
Routes of metastasis for melanoma
Lymphatics, Blood (Brain, Liver, Bone)