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Oral Path 2, Exam 2 > Salivary Gland Neoplasms > Flashcards

Salivary Gland Neoplasms Flashcards

(64 cards)

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1
Q

3 benign salivary neoplasms

A
  1. Pleomorphic adenoma
  2. Papillary cystadenoma lymphomatosum (Warthin tumor)
  3. Canalicular adenoma
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2
Q

5 malignant salivary neoplasms

A
  1. Mucoepidermoid carcinoma
  2. Polymorphous adenocarcinoma
  3. Adenoid cystic carcinoma
  4. Acinic cell carcinoma
  5. Carcinoma ex-pleomorphic adenoma
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3
Q

Salivary gland neoplasms have a slight ___ predilection

A

Female

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4
Q

Most common site for salivary gland neoplasms

A

Parotid gland

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5
Q

Most common minor gland for salivary gland neoplasms

A

Palate

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6
Q

Most common site for malignancy in major glands

A

Sublingual gland

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7
Q

Most common site for malignancy in minor glands

A

Retromolar region and tongue

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8
Q

“Benign mixed tumor”

A

Pleomorphic adenoma

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9
Q

Most common salivary gland neoplasm

A

Pleomorphic adenoma

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10
Q

___% of Pleomorphic adenomas are in the ___ gland

A

80%, Parotid

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11
Q

Pleomorphic adenomas are ___ unless they’re in the palate

A

Moveable

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12
Q

Palatal Pleomorphic adenomas are usually located:

A

Lateral to the midline

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13
Q

Treatment for Pleomorphic adenoma in the parotid gland

A

Remove lesion with the involved LOBE

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14
Q

Treatment for Pleomorphic adenoma in the submandibular gland

A

Remove lesion and the involved GLAND

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15
Q

Treatment for Pleomorphic adenoma in the hard palate

A

Remove lesion, including overlying mucosa down to periosteum

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16
Q

Treatment for Pleomorphic ademoma in the soft palate, labial and buccal mucosa

A

Enucleation

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17
Q

___% of Pleomorphic adenomas undergo malignant transformation if not removed

A

5%

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18
Q

Which location has more Pleomorphic adenoma recurrences: Parotid or Minor glands?

A

Parotid

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19
Q

“Warthin Tumor”

A

Papillary cystadenoma lymphomatosum

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20
Q

Myoepithelial cells in Pleomorphic adenoma may appear plasmacytoid or spindled and can produce:

A

Myxoid stroma, hyaline material, cartilaginous material, or even osteoid

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21
Q

What does Papillary cystadenoma lymphomatosum probably arise from?

A

Salivary duct epithelium entrapped in parotid lymph nodes during development

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22
Q

Papillary cystadenoma lymphomatosum is almost exclusively in the ___ gland (esp. the ___)

A

Parotid, tail

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23
Q

Papillary cystadenoma lymphomatosum has a strong association with _____

A

Smoking

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24
Q

Papillary cystadenoma lymphomatosum shows cystic spaces containing ____ ___

A

Serous fluid

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25
Treatment for Papillary cystadenoma lymphomatosum
Surgical excision
26
Prognosis for Papillary cystadenoma lymphomatosum
Good, low recurrence
27
Proliferation of one cell type
Monomorphic adenoma
28
The term "monomorphic adenoma" was replaced by ___ ___
Canalicular adenoma
29
Canalicular adenoma is more common in ____ glands, especially ____ ___ ___
Minor, upper labial mucosa
30
What do central mucoepidermoid carcinomas likely arise from?
Odontogenic epithelium containing mucous cells (found in odontogenic cyst lining)
31
Treatment for Canalicular adenoma
Enucleation
32
Prognosis for Canalicular adenoma
Excellent
33
Most common salivary gland malignancy
Mucoepidermoid carcinoma
34
Most common salivary gland malignancy in children
Mucoepidermoid carcinoma
35
Minor gland usually involved in Mucoepidermoid carcinoma
Palate and Retromolar area
36
Most common salivary gland malignancy in the lips, FOM, tongue
Mucoepidermoid carcinoma
37
What should be considered a Mucoepidermoid carcinoma until proven otherwise?
Mucocele-appearing lesion in the retromolar area
38
What must Mucoepidermoid carcinoma show in the histology?
Intracellular mucin
39
True/False: PAC can have a variety of growth patterns
True
40
What stains for intracellular mucin?
Mucicarmine
41
Treatment for low-grade Mucoepidermoid carcinoma
Wide surgical excision
42
Treatment for high-grade Mucoepidermoid carcinoma
Wide surgical excision plus radiation
43
< ____ cm Mucoepidermoid carcinomas have an excellent prognosis
2.5
44
2nd most common minor salivary gland malignancy
Polymorphous Adenocarcinoma (PAC)
45
PAC is well-demarcated initially, and then becomes ___
Infiltrative
46
PAC is almost exclusively in ___ glands
Minor
47
True/False: PAC can have a variety of growth patterns
True
48
The lesional cells of PAC are usually ____
Bland
49
PAC can be confused with ____ ____ carcinoma or ____ ____ ____ adenoma
Adenoid cystic carcinoma or carcinoma ex-pleomorphic adenoma
50
Treatment for PAC
Wide surgical excision
51
50% of all minor salivary gland ___ ___ ____ are in the palate
Adenoid cystic carcinomas
52
In Adenoid Cystic Carcinoma, the ___ and ___ gland are equally effected
Parotid and Submandibular
53
Most common malignancy in the submandibular gland
Adenoid Cystic Carcinoma
54
Pain is associated with this carcinoma and NSAIDs are unhelpful
Adenoid Cystic Carcinoma
55
3 growth patterns of Adenoid Cystic Carcinoma
1. Tubular (well-differentiated) 2. Cribriform (classic "Swiss cheese" - intermediate) 3. Solid (poorly-differentiated)
56
Histology of Adenoid Cystic Carcinoma
1. Hyperchromatic basaloid cells 2. Minimal cytoplasm 3. Little pleomorphism 4. Little mitotic activity
57
Treatment for Adenoid Cystic Carcinoma
Wide surgical excision and radiation
58
Prognosis for Adenoid Cystic Carcinoma
Generally poor
59
What route do most Adenoid Cystic Carcinomas metastasize by?
Blood
60
Most acinic cell carcinomas are in the ____ gland
Parotid
61
Acinic cell carcinomas often appear _____ (histology)
Psuedoencapsulated
62
Malignancy: patient is usually aware of a long-standing, asymptomatic mass that suddenly becomes tender
Carcinoma ex-pleomorphic adenoma
63
What do you see in the histology of carcinoma ex-pleomorphic adenoma?
Carcinomatous elements that arise in areas of benign pleomorphic adenoma
64
Prognosis for carcinoma ex-pleomorphic adenoma
Guarded

Oral Path 2, Exam 2 (6 decks)

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