Flashcards in menopause HRT Deck (39)
signs and symptoms of hypoestrogenic state
menstrual cycle alterations (dysfunctional bleeding)
mood/sleep/acute cognitive changes
indications for non hormonal
cessation of menstruation for ______ year (s)= menopause
menopause before 40 is
premature ovarian failure
FSH goes up or down with menopause?
up up up because of lack of negative feedback
maximum germ cells at what week?
20 weeks gestation
why does estrogen, progesterone decline?
decrease in granulosa cells
pure antagonists or partial antagonists take advantage of the fact that
Estrogen receptors can be fully activated, partially activated, not activated
endometrial hyperplasia risk
put on low dose OCP
most common symptom 3-5 years into menopause
25% beyond 5 years
why do hot flashes occur?
increased core body, skin blood flow, heart rate
who gets the most hot flashes?
ERT and HRT within 2-3 weeks help reduce severity of
alternative approaches to hot flashes
Vitamin E, dong quai, black cohash
sleep quality affected by
hot flashes and sleep makes the mood worse
cystocele, rectocele, prolapse increase as
vagina and vulvar epithelium thins
when does vaginal dryness occur?
1-3 years post menopausal
estriol is E
E1, formed with enzymes from adrenal of fetus
estrone is E produced
E3 in adipose, MOST COMMON DURING MENOPAUSE peripherally
estradiol is E and is the
E2 most common, from the dominant follicle/corpus luteum
micronized 17beta estradiol forms?
tablet, cream, patch, ring
micronized progesterone is
breaking down more bone than making it leading to less dense bone
why does calcium not work with Ca supplements
stromal structure that holds the calcium gets less dense. Existing bone is stronger but doesn't reduce risk of breaking from stromal insufficiency
what affects survivability of patients with osteoporosis
breaking a hip (50* mortality)
loss of bone but no increase of fracture, not as raised T score (middle score)
risk factors for osteoporosis
osteoporosis management for normal, osteopenia, osteoporosis
osteopenia without fracture hx: no tx
osteopenia with fracture hx: treat