Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Metronidazole > Flashcards

Metronidazole Flashcards

1
Q

MOA?

A

Diffuses into the cell then reduced to a free radical under anaerobic conditions interfering with the organisms DNA causing breakage, destabilisation and cell death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Bacteriostatic or bacteriocidal?

A

Bacteriocidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What bacteria are they used against?

A

Anaerobes and some protozoa (giardia), kills campylobacter some clostridia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What conditions is it used for?

A

Inflammatory bowel disease and enteric infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What drug is it used in combination with to treat periodontal disease in dogs?

A

Spiramycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Resistance?

A

Antinomyces may be resistant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are they not useful against?

A

Aerobes and microaerophiles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe absorption, distribution and elimination?

A

A - moderately lipophilic and well absorbed in GIT tract
D - well in CNS, bone, seminal fluid and even pus-filled cavities
E - urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Adverse effects?

A

Can cause GIT upset - stomatitis

Can see neurological toxicity: ataxia, nystagmus, head tilt, rolling over and over

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

can this be used in food producing animals?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Pharmacology (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions