Microalbuminuria and C peptide Flashcards

1
Q
  • one of the smallest proteins found in the circulation
A

Microalbuminuria

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2
Q
  • if the permeability of the glomerulus increases, one of the first type protein excreted out of the urine is albumin
A

Microalbuminuria

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3
Q

: similar to Albuminuria

A
  • Protenuria
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4
Q
  • smallest protein; first to be excreted
A

Albumin

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5
Q
  • increase in urinary albumin: early sign of
A

diabetic renal nephropathy

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6
Q

persistent hyperglycemia

A

diabetic renal nephropathy

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7
Q

DM is poorly controlled

A

diabetic renal nephropathy

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8
Q

renal tubules are exposed to high plasma glucose conc

A

diabetic renal nephropathy

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9
Q

Glucose presented in the renal tubules is too high
- inability to reabsorb [?] (also excreted out of the urine)
- positive for [?]

A

albumin
protein

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10
Q
  • most common cause of death
A

renal failure

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11
Q

Detection: assist in early diagnosis before the development of

A

heavy protenuria

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12
Q

Kidneys excrete a large amount of protein

A

heavy protenuria

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13
Q

heavy protenuria normal value

A

> 0.5g/day

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14
Q

Diagnosis: when [?] specimen collected within [?] are abnormal

A

2 out of 3
6 months

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15
Q
  • pro-insulin cleaved to give C-peptide and insulin
A

C peptide

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16
Q
  • reflects endogenous insulin production
A

C peptide

17
Q
  • useful in the differential diagnosis of diabetes mellitus type 1 and type 2
A

C peptide