Microbiology Chapter 15 Flashcards Preview

Microbiology > Microbiology Chapter 15 > Flashcards

Flashcards in Microbiology Chapter 15 Deck (21)
Loading flashcards...
1
Q

Any molecule that stimulates an immune response

A

Antigen (Ag)

2
Q

B Cell receptor is what kind of a molecule?

A

Immunoglobulin (Ig)

3
Q

B cells receptors are secreted as what?

A

Antibodies (Ab = Ig)

4
Q

What is never secreted?

A

T-Cell receptor (TCR)

5
Q

List the Antigen Presenting Cells (APC)

A

Macrophages, B-Cells, and Dendritic Cells (Macrophage-like cell in tissue)

6
Q

What are the functions of APC?

A

Process and present antigen in association with MHC II (cell surface protein on host cells). T-Cell receptor recognize antigen/MHC complex.

7
Q

Thought to secrete interleukin; a cytokine which suppresses helper T-Cells

A

Regulatory B-Cell

8
Q

Secreted protein that regulates other cells

A

Cytokine

9
Q

Immunoglobulin classes

A

IgG, IgA, IgM, IgD, IgE

10
Q

Based on the Fc (constant region) fragment

A

Isotopes

11
Q

Most prevalent in tissue fluid and blood. Only one to cross Placenta.

A

IgG

12
Q

Monomer or dimer (secretory IgA). Dimer - two Ig held together by a J chain. Secretory IgA is there for local immunity (salivary glands, intestine, nasal membrane, breast, lung, genitourinary tract. Provides protection for newborns.

A

IgA

13
Q

Pentomer (five monomers). First to be synthesized during primary immune response. Associated with complement activation. Circulates in the blood

A

IgM

14
Q

Monomer. Small amounts in the serum (rarely secreted). Receptor for antigen on B-cells is its only function.

A

IgD

15
Q

Activates during allergies and parasite infections.Constant region binds to mast cells and basophils which release chemical mediators that aid inflammation.

A

IgE

16
Q

Direct Involvement of T-Cells. Produce and react to cytokines. Activated simultaneously with B cell activation. Subset of T cells have unique CD receptors (CD4, CD8)

A

Cell-Mediated Immunity

17
Q

Types of T-cells

A

Helper T-cells (TH) CD4+

Cytotoxic T cells (TC) CD8+

18
Q

What helps T-cell bind to Ag on MHCII

A

CD4

19
Q

Binds and lyses infected cells and cancer cells

A

Cytotoxic Cells

20
Q

T-helped cell binds to Ag plus MHC II on antigen presenting cell.

A

TH cell Activation

21
Q

T-cytotoxic cells binds to Ag plus MHC I on target cells (cells to be killed)

A

TC Activation