microscopic osteology and myology Flashcards

1
Q

Functions of skeletal sys (6)

A

support
mineral storage
hemopoiesis
protection
body movement -levers
fat and stem cells

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2
Q

What are the specialised cells of mature bone (4)

A

osteocytes -maintain bone
osteoblasts -bone making
osteoprogenitor -stem
osteoclasts -bone breakdown

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3
Q

where are osteoblasts on bone usually

A

outer and inner surface

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4
Q

where are osteoclasts on bone usually

A

outer and inner surface

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5
Q

where are epiphysis and what do they contain

A

end of bones and contains red bone marrow

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6
Q

diaphysis where and what contain

A

shaft of bone and contains yellow bone marrow

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7
Q

metaphyses

A

connects epiphysis and diaphysis

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8
Q

what are the two protective layers on bone

A

periosteum and endosteum

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9
Q

describe the periosteum structure and location

A

comprised of an outer fibrous layer and inner osteogenic layer. located on outer surface of bone

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10
Q

describe the endosteum

A

located on the inner surface of bone, it is an incomplete layer of osteoblasts, osteoprogenitors and osteoclasts

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11
Q

what are the roles of periosteum (5)

A

isolate bone
protect bone from surrounding
attachment for nerve and blood vessels
participate in bone growth and repair
attaches bone to connective tissue

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12
Q

what is another term for osteogensesis

A

ossification

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13
Q

before 6 weeks of development, bone is _______

A

cartilage

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14
Q

what is intra membranous ossification?

A

bone forms from inside mesenchyme(stem) or fibrous connective tissues.

ex. roof of skull

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15
Q

what is endochondral ossification.

A

bone from hyaline cartilage. usually involves a bone growing in length

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16
Q

describe the 7 stages of endochondral ossification

A

stage 1
chondrocytes disintegrate a cavity inside the diaphysis of hyaline cartilage

stage 2
periosteum formed first and vascularity is developed (hyaline cartilage lack vascularity)

stage 3
diaphysis development starts from the inside out starting with spongy bone in the primary ossification centre.

stage 4
diaphysis completed to metaphysis

stage 5
secondary ossification centres form in epiphysis

stage 6
Bone grows in length when chondrocytes on the epiphyseal side continue to to divide and grow in size. The osteoblasts on the diaphysial side chase the chondrocytes and replace them with bone.

stage 7
Bone is complete with articular cartilage being remnants of the cartilage and a epiphyseal line being created.

17
Q

How does bone grow in width

A

like a tree outwards. If it must go around a blood vessel it can form ridges and surround the vessel

18
Q

What are the 4 properties of muscle tissue

A

excitability, contractility, extensibility, elasticity

19
Q

what is the order of skeletal muscle organisation

A

muscle, fascicle, fibre, myofibril, sarcomere

20
Q

what is skeletal muscle surrounded by

A

epimysium

21
Q

what are fascicles surrounded by

A

perimysium

22
Q

what are muscle fibres surrounded by

A

endomysium

23
Q

What is the A band of a sarcomere

A

full length of myosin thick filament

24
Q

what is the M line of a sarcomere

A

perpendicular myosin

25
Q

what is the H band of a sarcomere

A

myosin only

26
Q

what is the I band of a sarcomere

A

Actin thin filament only

27
Q

what happens to the H and I bands when a muscle shortens?

A

they shorten

28
Q

what happens to the H and I bands when a muscle relaxes

A

they lengthen

29
Q

What is the thin filament composed of

A

g actin, troponin, tropomyosin around a nebulin fibre

30
Q

what is the site of neural control for muscle fibres

A

motor end plate

31
Q

what is a motor unit comprised of

A

motor neuron and the fibres it innervates