Midterm 2 Flashcards
(83 cards)
mastitis
inflammation of the mammary gland
4 classic symptoms of mastitis
- swelling
- heat
- redness (or becomes bruise)
- tenderness (pain)
annual dollar loss due to mastitis
$ 1.5 - 2 billion
cost dollar loss due to
- milk income loss (65%)
- treatment costs
- culling losses
- discarded milk
clinical mastitis
observable (SHRT)
subclinical mastitis
unobservable
mild clinical degree of mastitis
- milk altered: no
- udder affected: maybe
- cow abnormal: no
severe clinical degree of mastitis
- milk altered: yes
- udder affected: yes
- cow abnormal: maybe
parachute (systemic) mastitis
- milk altered: yes
- udder affected: yes
- cow abnormal: yes
- caused by coliform and s. aureus
major mastitis causing pathogens
- coliform organisms
- environmental strep
- staph aureus (MRSA)
- strep ag
environmental organisms
- live in cows environment/ bed/ water/ fecal
- most often occur inbtwn milkings
- strep dysgalactiae
- strep uberis
- coliform organisms (fecal/ ecoli)
contagious organisms
- spread from poor milking techniques, faulty milking equipment, or improper sanitation
- staph aureus
- strep ag
strep ag
- only pathogen that can permanently be eliminated from herd
- can only survive outside of cow for few seconds
how many somatic cells does normal milk have
100,000 - 200,000 cells/ml
more in mastitis milk
macrophage
- white blood cell / leucocyte
- gate keeper/ 1st responder, signals to PMN
- found in uninfected mammary gland
PMN (polymorphonuclear neutrophils)
- white blood cell / leucocyte
- get called in by macrophages after infection to destroy pathogens
- found in infected mammary gland
dead secretory cells
- productive cells dying off
- not defensive
- fewest number of cells
how many somatic cells does mastitic milk have
500,000 - 4,000,000 cells/ml (salty)
mastitic milk vs normal
mastitic:
-more PMN than macrophage somatic cell count
normal:
-more macrophages than PMN
phagocytosis
-process of phagocytes (macrophages and PMN) searching out, ingesting and killing foreign bacteria
why do cows get infections
- insufficient number of leucocytes (previous or current infection, stress with calving)
- leukocytes not functioning properly (blood vs milk differences, hormone influence)
mastitis detection tests
- evaluate blood mammary gland leakage
- somatic cell count (SCC)
high scc / mastitic milk
- decrease because produce ate a lower rate (fat, lactose, total casein)
- increase of blood born components (sodium, chloride)
tests on bulk milk
- SCC (can detect bug, but not specifically which one)
- direct bacteriological screening (grow bacteria to tell pic bug) $$
- conductivity, lactose, NAGase, BSA tests