Midterms Flashcards

(110 cards)

1
Q

The second hardest mineralized tissue

A

dentin

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2
Q

most prominent in the tooth, lies between the
enamel & the pulp chamber near the
dentinoenamel junction (DEJ).

A

Primary dentin

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3
Q

It outlines the pulp chamber and referred to as

A

circumpulpal dentin

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4
Q

It is mineralized and in the structural inter-
relation between the collagenous and
noncollagenous matrix components.

A

Primary dentin

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5
Q

the outer layer closest to enamel is known as

A

mantle dentin

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6
Q

Formed after root formation is complete, normally
after the tooth has erupted and is functional.

A

secondary dentin

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7
Q

It grows much more slowly than primary dentin but
maintains its incremental aspect of growth.

A

secondary dentin

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8
Q

this is important in determining the
form of cavity preparation for certain dental
restorative procedures.

A

pulp recession

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9
Q

produced in reaction to various stimuli, such
as attrition, caries, or a restorative dental
procedure.

A

tertiary dentin

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10
Q

it is produced by those cells directly affected
by the stimulus not like primary and secondary
dentin where it forms along the entire pulp-
dentin border.

A

tertiary dentin

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11
Q

the cells forming tertiary
dentin line its surface or become included in
the dentin.

A

osteodentin

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12
Q

tertiary dentin is also referred to as

A

reactive ot reparative dentin

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13
Q

dentin begins at what stage of tooth development

A

bell stage

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14
Q

dentin formation spreads down the cusp slope
as far as the ____ of the enamel
organ, and the dentin thickens until all the
coronal dentin is formed.

A

cervical loop

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15
Q

are specialized cells that produce dentin through the
secretion of its collagenous and noncollagenous organic matrix
components and by controlling the mineralization process.

A

odontoblasts

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16
Q

odontoblasts and fibroblasts slowly move towards the center of the tooth
by growing a protrusion from themselves,
which stays in place, embedded within the matrix, while the rest of the
cell moves toward the center of the tooth, towards the pulp. What is this process called

A

odontogenic processes

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17
Q

The odontogenic processes secrete _______ , which
forms crystals and mineralizes the predentin

A

calcium hydroxyapatite

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18
Q

In dentinogenesis, the odontoblasts secrete a soft organic matrix made out of proteins,
which is called

A

predentin

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19
Q

Fibroblasts assist by creating a mesh
of thick collagen fibers, called
_____ which become the
framework for dentinogenesis

A

Korff’s fibers

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20
Q

are thick collageneous fibers in the
developing tooth that begin in the dental papilla, spiral between the cells of the
odontoblast layer, and form the matrix of the dentin.

A

Korff fibers, also von Korff

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21
Q

As the odontoblasts continue to increase in
size, they produce smaller collagen type 1
fibrils, oriented parallel to the future DEJ. In
this way, what layer appears

A

mantle predentin

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22
Q

The plasma membrane of odontoblasts
adjacent to the differentiating ameloblasts
extends stubby processes into the forming

A

extracellular matrix

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23
Q

One of these processes may penetrate the
basal lamina and interpose itself between
the cells of the IEE to form the

A

enamel
spindle

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24
Q

As the odontoblasts forms these processes,
it also buds off membrane bound vesicles

A

matrix vesicles

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25
The odontoblasts develop a cell process called the __________ which is left behind in the forming dentin matrix as the odontoblasts moves toward the pulp.
odontoblast process or Tomes fiber
26
is formed after root formation is completed by the same odontoblasts that form primary dentin
Secondary Dentin
27
extend through the entire thickness of the dentin from the DEJ to the mineralization front and form a network for the diffusion of nutrients throughout the dentin.
dentinal tubules
28
has been shown to be hypermineralized compared to the intertubular dentin though precise composition is still not known
peritubular dentin
29
composes the main body of dentin
intertubular dentin
30
It is located between dentinal tubules or, more specifically, between the zones of peritubular dentin
intertubular dentin
31
Term used to describe areas of unmineralized or hypomineralized dentin where calcospherites (globular zones of mineralization) have FAILED to fuse into a homogeneous mass within mature dentin.
interglobular dentin
32
It is most common in circumpulpal dentin (just below the mantle dentin).
interglobular dentin
33
Dentinal tubules which have become occluded with calcified material
Sclerotic dentin
34
When the dentin of the root is viewed in Ground Sections under transmitted light, an area called ______ can be seen just below the surface of the dentin where the root is covered by cementum.
granular layer of Tomes
35
soft connective that supports the dentin
pulp
36
four distinct zones of pulp
odontoblastic zone cell-free zone cell-rich zone pulp core
37
principal cells of the pulp
odontoblast, fibroblasts, undifferentiated ectomesenchymal cells, immunocompetent cells
38
It forms the natural barrier between the mineralized tissues. Its active phase, prominent organelles and resting phase smaller cells with fewer organelles.
ODONTOBLAST
39
The most abundant cells in the pulp. It maintains and form the pulp matrix.
FIBROBLASTS
40
Referred to as "reserve cells" ,capable of maturing into macrophages.
UNDIFFERENTIATED ECTOMESENCHYMAL CELLS
41
Has macrophages, Dendritic cells, and lymphocytes
IMMUNOCOMPETENT CELLS
42
- suggests that the dentin is innervated directly. - It is not exactly the nerves that are simulated. - It is the odontoblast itself that serves and acts as a receptor.
Transduction Theory`
43
- suggests that the odontoblast acts as a receptor. - The sensitivity is caused by the movement of the dentinal tubules contents. - Movement of fluid will cause sensitivity.
Hydrodynamic Theory
44
- suggests that the receptors at the base of odontoblasts are stimulated directly or indirectly by fluid movement through the tubules. - Any stimulation of the nerve endings found in the dentinal tubules will be the one to receive
Direct Conduction Theory
45
Also referred to as denticles
pulp stone
46
Frequently found in pulp tissue, more common at the orifice of the pulp chamber or within the root canal.
pulp stone
47
- Progressive narrowing of the pulp space - Due to the continuous deposition of dentin - When pulp is getting thicker, pulp cavity becomes smaller
PULP RECESSION
48
decrease in size of the pulp due to structural
ATROPHY OF PULP
49
deep carious lesions
CHRONIC PATHOLOGICAL PROCESSES
50
deep carious lesions
CHRONIC PATHOLOGICAL PROCESSES
51
differentiating ameloblasts acquire their phenotype, change polarity, develop an extensive protein synthetic apparatus, and prepare to secrete the organic matrix of enamel. What is this stage
presecretory stage
52
during this stage, ameloblasts elaborate and organize the entire enamel thickness, resulting in the formation of a highly ordered tissue.
secretory stage
53
ameloblasts modulate and transport specific ions required for the concurrent accretion of mineral. Ameloblasts now are considered to be cells that carry out multiple activities throughout their life cycle and that upregulate or downregulate some or all of them, according to the developmental requirements. What stage is this
maturation stage
54
The function of ameloblasts during this stage is determination of shape of the tooth.
Morphogenetic stage - presecretory stage
55
The inner enamel epithelium interacts with underlying connective tissue and through differential growth helps to establish the dentino-enamel junction and thereby determine the shape of the tooth to be formed.
Morphogenetic stage - presecretory stage
56
During this stage, the inner enamel epithelial cells undergo differentiation to ameloblasts as a prerequisite for enamel formation.
differentiation stage - presecretory stage
57
This stage is also named as organizing stage because during this stage, the ameloblasts exert organizing influence on dental papilla cells which are adjacent to them and help in their differentiation to odontoblasts.
differentiation stage - presecretory stage
58
In this stage, ameloblasts perform the function of secretion of enamel matrix and partial mineralization.
secretory stage
59
During this stage, ameloblasts helps in the mineralization and maturation of enamel.
maturation stage - post-secretory stage
60
In this stage, ameloblasts have to introduce the inorganic material necessary for maturation and also reabsorb proteins and water to provide space for the minerals.
maturation stage - post-secretory stage
61
In this stage, ameloblasts along with other layers of enamel organ has to perform a protective function.
protectice stage - post-secretory stage
62
what covers the newly formed enamel and protects it in post-secretory stage
reduced enamel epithelium
63
In this stage the reduced enamel epithelium secretes collagenase enzyme which destroy the connective tissue between oral mucosa and erupting tooth.
desmolytic stage - post-secretory stage
64
During this stage the reduced enamel epithelium proliferates and fuses with the oral epithelium to form a solid plug of epithelial cells.
65
During this stage the reduced enamel epithelium proliferates and fuses with the oral epithelium to form a solid plug of epithelial cells.
desmolytic stage - post-secretory stage
66
During this stage the reduced enamel epithelium proliferates and fuses with the oral epithelium to form a solid plug of epithelial cells.
desmolytic stage - post-secretory stage
67
2 step process of enamel formation
- enamel matrix deposition - enamel matrix mineralization
68
The secretory ameloblasts which are structurally suited for synthesis and secretion of enamel proteins, start secretory function after a layer of dentin is deposited. The
enamel matrix deposition
69
small to normal tops (crowns) of the teeth, upper and lower teeth that do not meet showing a poor bite, and teeth that vary in color from off-white to yellow-brown. The enamel thickness varies from thin and smooth to normal, with grooves, lines and/or pits.
Hypoplastic (Type 1)
70
exhibits a normal thickness of the enamel, but its density is the same as that of dentin. Commonly associated with an open bite and creamy white to yellow-brown roughly surfaced teeth that may be tender and sore. The enamel is generally normal in thickness but tends to be chipped away or scraped.
Hypomaturation (Type 2)
71
imperfection in the formation of enamel
amelogenesis imperfecta
72
enamel thickness is normal, but its density is even less (more radiolucent) than that of dentin. Patients with an open bite and creamy white to yellow-brown rough enamel-surfaced teeth that may be tender and sore. These teeth usually carry substantial precipitates of stony material from the fluids of the mouth (calculi). The enamel is generally normal in thickness but tends to be chipped away or scraped.
Hypocalcified (Type 3) -
73
smaller than normal teeth, the color of which may range from white to yellow-brown, and teeth that appear to be mottled or spotted. The enamel is thinner than normal with areas that are clearly less dense (hypomineralized) and pitted.
Hypomaturated-hypoplastic with taurodontism (Type 4)
74
formative cell of dentin
odontoblast
75
formative organ of dentin
dental papilla
76
embryonic origin of dentin
ectomesenchyme
77
The ______ from what used to be as dental papilla is due to the expression of signaling molecules and growth factors in cells of IEE.
Odontoblast differentiation
78
containing fine collagen fibrils, separates undifferentiated cell of dental papilla (preodontoblasts) from differentiating IEE (ameloblasts)
acellular zone
79
formation of mantle dentin
deposition of matrix and mineralization
80
An avascular hard tissue that covers the roots of teeth from CEJ to apex
cementum
81
2 development of cementum
prefunctional and functional stage
82
A development stage of cementum that occurs during root formation
Prefunctional Stage
83
A development stage of cementum that occurs throughout occlusion and life
functional stage
84
types of cementum
acellular and cellular
85
a type of cementum that is for attachment of teeth to PDL
acellular cementum
86
a type of cementum that is for the continuous repair and movement of periodontium
cellular cementum
87
functions of cementum
anchorage, coverage, compensation, eruption and resorption and repair
88
Formerly called as “Coronal Cementum" A mineralized matrix that contains neither collagen fibers nor cementocytes
acellular afibrillar cementum
89
Referred to as “ Secondary Cementum” Contains both extrinsic Sharpey’s fibers & intrinsic bundles of collagen fibers in the cementum
CELLULAR MIXED FIBER CEMENTUM
90
Formerly called as “Primary Cementum ” or “Fibrous Cementum” - Consists of Sharpey’s Fibers - Extrinsic collagen fibrils
ACELLULAR EXTRINSIC FIBER CEMENTUM
91
- Contains both cementocytes & intrinsic bundles of collagen fibrils - Products that are specific to cementoblasts - Formed only during reparative process
CELLULAR INTRINSIC FIBER CEMENTUM
92
- A thin, non-cellular, amorphous layer of hard tissue (10 μm thick) - The first layer deposited - Deposited in the epithelial root sheath's inner layer - Seals the tubules of dentin - Composed of enamelin instead of collagen
INTERMEDIATE CEMENTUM
93
spaces within the matrix which houses the cell bodies of cementocytes
lacunae
94
elongated, tiny spaces housing the processes
Canaliculi
95
- Collagen fiber formed by fibroblasts of the PDL - Referred to as extrinsic fibers. - Partly incorporated into the cementum.
sharpey's fibers
96
The cementoblasts also lay down fine collagen fibers in the cementum
Intrinsic Fibers
97
- growth lines of cementum - parallel with the cementum surface - cementum is laid down at intervals as evidenced by the appearance of resting lines (light & dark banding pattern) in the cementum - These lines indicate alternating periods of deposition and lack of deposition of cementum.
Incremental Lines of Salter
98
- Form the cementum - Found lining the root surface Interposed between bundles of PDL - a cell found in cementum
Cementoblasts:
99
- Cementoblasts that are trapped in the lacunae during its development - Sparse amount of cytoplasm and numerous processes occupying the canaliculi in the mineralized cementum matrix
Cementocytes
100
morphology of CEJ
30% percent of human teeth 10% have gaps between cementum and enamel 60% of the cementum overlaps the enamel
101
- Also known as excementosis - characterized as the excessive cementum formed usually along the apical portion of root - can cause difficulty in execution of certain dental procedures (e.g. tooth extractions, root canals etc.)
HYPERCEMENTOSIS
102
steps in cementum formation
matrix deposition and mineralization
103
- Extension of the cervical loop (OEE+IEE) - This bilayered sheath has dental papilla on one side and dental sac on the other side.
Hertwig’s Epithelial Root Sheath (HERS)
104
- It sends signals to the dental papilla to differentiate into odontoblasts - The odontoblasts start depositing the radical dentin. - The root dentin deposition sends signals for the differentiation of cementoblasts
Hertwig’s Epithelial Root Sheath (HERS)
105
this degeneration exposes the ectomesenchymal cells of the dental sac to the radical dentin = deposit cementum
cells of the dental follicle
106
the cells of HERS starts degenerating
CELLS OF THE DENTAL FOLLICLE
107
the HERS receives signals that form the epithelial mesenchymal transformation differentiate into cementoblasts = deposit cementum
CELLS OF HERS
108
FORMATION OF CELLULAR INTRINSIC FIBER CEMENTUM
CELLS OF THE DENTAL FOLLICLE
109
FORMATION OF ACELLULAR INTRINSIC FIBER CEMENTUM
CELLS OF HERS
110
an outermost thin layer of non-mineralized cementum just adjacent to the cementoblast
cementoid