Minerals Flashcards
(31 cards)
Define mineral
Inorganic element requires as nutrients
What are the 2 groups of of minerals and define them?
Macrominerals: required in greater proportions by animals
Microminerals: required in small proportions by animals
Calcium functions?
- second messenger
- enzyme activator
- bone mineralization
Calcium deficiencies?
Hypocalcemia in cows
Milk fever
Parturient pariesis
Calcium regulations has how many pathways?
2
what are the 2 pathways of absorption?
- Passive: between cells and the tight junction. Diffusion of Calcium (high to low concentration)
- Active transport: In the brush boarder (TRPV 6 and TRPV 5). Mobilized from the lumen to the cytosol in the cell; to the basal membrane. From there, (1) PMCA to transported to the outside (2) NCX1 transport in basal membrane. Transport Ca OUTSIDE and Na INSIDE.
Functions of phosphorous
- bone mineralization
- oxidative phosphorylation
- Acid-base buffer
- DNA and RNA
- Phospolipids
- Singaling molecules
- Reversable modiciation of proteins
- Enzymatic reactions
Deficiency of phosphorous can be seen via?
Rickets
PICA: when animals are picking on things; will start chewing rocks or wood; it can happen when an animal does not recieve enough phosphorous or fiber— behavioral changes; animals are trying to find it in the ground.
Ca:P ratio
They are mobilized together for mineralization. IF NOT ENOUGH phos. proivded, animals won’t be able to deposit Ca in the bones, and leads to issues.
Functions of Magnesium
- Anion charge neutralization
- Cellular energy metabolism
- Nucleic acid and protein synthesis
- Second messenger
- Ion channels
Deficiences of Mg can be seen via?
Grass tetany
convulsions
muscle twitching
Sodium, Potassium, and Chloride are what?
Electrolytes: improve acid base balance in cells
Functions of Na, K, and Cl?
- nutrient transport
- membrane potentials
- extracellular fluid volume
Deficiences of Na+, Cl, K are seen as?
- Irregular heartbeat
- Vomiting
- Diarrhea
Iodine function?
Thyroid hormone synthesis
Defiecieny of Iodine can be seen via?
Goiter: mass in the trachea, the lining where the tyroid gland is
What is the function of selenium?
- Selenoproteins
~Glutathionine peroxidases: this enzyme inhibits and destroys natrually occuring peroxides that cause cell damage
~Deidinases: mediate the activeation and inactivation of thyroid hormone
~Selenoprotein P: protect aganist oxidative injury and to transport selenium from the liver to perpheral
~Selenoprotein W: antioxidant
Toxicity of Selenium results in?
- Blind staggers
- Abnormal hoof and hair growth
Deficiency of selenemium results in?
- White muscle liver disease
- Liver necrosis
This mineral is stored bound to ferritin, transported bound to transferrin
Iron
What are the function of Iron?
- Heme proteins
-hemoglobin
-myoglobin
-catalase - Proteins with Iron-sulfer centers
-aconitase
What are the functions of zinc?
- Zince metalloenzymes
-aminopeptidase
-fructose 1,6-biphosphate - Zinc finger proteins
- Lymphocytes
Deficiences of Zinc lead to?
- Decreased Growth
- Dermatitis
Function of Copper?
- Cu metalloenzymes
- Neutrophils and T Lymphocytes
- Iron metabolism
- Bone and vascular function