Misc Flashcards
(25 cards)
iso chromosome
breaks at centromere
FISH
detect number and location of specific DNA sequences
- doesn’t need a dividing cell
- denature and hybridize
Dual color dual fusion FISH probe
1 red, 1 green, 2 fusions = translocation
2 red, 2 green = normal
Dual color, break apart FISH probe
2 Fusion = normal
1 fusion, 1 red, 1 green = translocation
EDTA and ACD function
serve as anticoagulants in blood
- can work for nucleic acid isolation
sucralfate
H2 receptor agonist
Treats GERD
Prokinetics
H2 receptor agonist
Treats GERD
Eikenella
bacteria associated with human bites
Capnocytophaga
bacteria associated with dog bites
Lactoperoxidase
enzyme in saliva that generates thiocyanate
- toxic to bacteria in the mouth
lactoferrin
binds iron so bacteria can’t use it
What area allows for the feeling of fullness when the stomach expands?
the fundus
What do chief cells secrete?
pepsinogen
What do parietal cells secrete?
HCl
What do D cells secrete?
somatostatin
What do G cells secrete?
Gastrin
What is the MOA H. pylori?
inflammation of the antrum leading to D cell inhibition and decrease of somatostatin –> inc HCl = duodenal ulcer
Peptic Ulcer symptoms
dyspepsia
abdominal pain
heartburn
complications
Reflux disease symptoms
dyspepsia
dysphagia
heartburn
complications (dental, barretts esophagous)
What do you use to treat mild reflux esophagitis?
H2 antagonist
What do you use to treat severe reflux esophagitis?
proton pump inhibitor
If h pylori turns into pan gastritis, what cancer is it prone to?
Gastric carcinoma
If H pylori turns into antral gastritis, what is it prone to cause?
Duodenal ulcer
If H. pylori leads to an increase of proliferating B cells, what cancer is it prone to?
MALT Lymphoma
