Misc Cardiac Flashcards

(54 cards)

0
Q

tPA

Another Name

A

Alteplase Recombinant

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1
Q

Alteplase Recombinant

Another Name

A

tPA, Activase

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2
Q
Alteplase Recombinant (tPA)
Class
A

Thrombolytic

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3
Q
Alteplase Recombinant (tPA, Activase) 
Description
A

Recombinant DNA- derived from human tPA hormone, tPA promotes thrombolysis by forming plasmin. Plasmin in turn degrades fibrin and fibrinogen and ultimately the clot.

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4
Q
Alteplase Recombinant (tPA, Activase) 
Indication
A

To thrombolyse in acute myocardial infarction acute ischemic stroke and pulmonary embolism.

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5
Q
Alteplase Recombinant (tPA, Activase) 
Contraindication
A

Active internal bleeding, suspected aortic dissection, traumatic CPR, recent hemmorhagic stroke (6 months), intracranial or intraspinal surgery or trauma (2 months), pregnancy, uncontrolled hypertension, or hypersensitivity to thrombolytics

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6
Q
Alteplase Recombinant (tPA, Activase) 
Precautions
A

Recent major surgery, cerebral vascular disease, recent GI or GU bleeding, recent trauma, hypertension, patient > 75 years, current oral anticoagulants, or hemmorrhagic ophthalmic conditions

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7
Q

Heparin

Class

A

Anticoagulant

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8
Q

Heparin

Description

A

Rapid onset anticoagulant, enhancing the effects of antithrombin III and blocking the conversion of prothrombin to thrombin and fibrinogen to fibrin

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9
Q

Heparin

Indication

A

To prevent thrombus formation in acute MI

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10
Q

Norepinephrine Bitartrate

Another Name

A

Levophed

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11
Q

Levophed

Another Name

A

Norepinephrine Bitartrate

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12
Q
Norepinephrine Bitartrate (Levaphed)
Class
A

Sympathomimetic, vasopressor

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13
Q
Norepinephrine Bitartrate (Levaphed)
Description
A

Potent alpha agonist resulting in intense peripheral vasoconstriction, positive chronotropic and increased inotropic effects ( from 10% beta effect) with increased cardiac output. Alpha-adrenergic activity resulting in peripheral vasoconstriction and beta adrenergic activity leading to inotropic stimulation of the heart and coronary artery vasodilation

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14
Q
Norepinephrine Bitartrate (Levaphed)
Indication
A

Cardiogenic Shock, unresponsive to fluid resuscitation, significant hypotension (<70 mm Hg) states

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15
Q
Norepinephrine Bitartrate (Levaphed)
Contraindications
A

Hypotensive patients with hypovolemia, pregnancy

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16
Q
Norepinephrine Bitartrate (Levaphed)
Precautions/Bradycardia
A

Bradycardia, hypertension, dysrhythmias, chest pain, peripheral cyanosis, tissue necrosis from extravasation

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17
Q
Norepinephrine Bitartrate (Levaphed)
Dose/Route
A

Dilute 8 mg in 500mL of D5W or 4 mg in 250mL D5W (16 ug/mL). Infuse by IV piggy-back at 0.1-0.5 ug/kg/min tritrated to response (average dose for 70kg patient 7-35 ug/min)

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18
Q
Norepinephrine Bitartrate (Levaphed)
Pedi Dose/Route
A

Begin at 0.1-2 ug/kg/min IV infusion, adjust rate to achieve desired change in blood pressure and systemic perfusion. Tritrated to patient response.

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19
Q

Tridil

Another Name

A

Nitroglycerin injection

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20
Q

Tridil (Nitroglycerin Injection)

Class

A

Vasodilator/Nitrate

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21
Q

Tridil (Nitroglycerin Injection)

Description

A

Relaxes blood vessels, increasing the blood and oxygen supply to the heart

22
Q

Tridil (Nitroglycerin Injection)

Indications

A

Infusions used to help relieve the pain associated with angina that does not respond to oral treatment, to control blood pressure; and to help congestive heart failure

23
Q

Tridil (Nitroglycerin Injection)

Contraindications

A

Hypotension, uncorrected hypovolemia, increased intracranial pressure, constrictive pericarditis and pericardial tamponade

24
Tridil (Nitroglycerin Injection) | Precautions
Headache, severe hypotension, reflex tachycardia
25
Tridil (Nitroglycerin Injection) | Dosage
0.2-1.5 mcg/kg/minute
26
Verapamil | Other Names
Isoptin, Calan
27
Verapamil (Isoptin, Calan) | Class
Calcium Channel Blocker
28
Verapamil (Isoptin, Calan) | Description
Calcium channel blocker that slows AV conduction, suppresses reentry dysrhythmias such as PSVT, and slows ventricular responses to atrial tachydysrhythmias. Dilates coronary arteries and reduces myocardial oxygen demand.
29
Verapamil (Isoptin, Calan) | Indications
PSVT refactory to adenosine, atrial flutter and atrial fibrillation with rapid ventricular response
30
Verapamil (Isoptin, Calan) | Contraindications
Severe hypotension, cardiogenic shock, 2nd or 3rd degree heart block, CHF,sinus node disease, and accessory AV pathways, WPW syndrome. It should not be administered to a person taking beta blockers
31
Verapamil (Isoptin, Calan) | Precautions
MI with coronary artery occlusion, myocardial stenosis.
32
Verapamil (Isoptin, Calan) | Dose/Route
2.5 to 5 mg IV bolus over 2-3 min, then 5-10 mg after 15-30 min to a max of 30 mg in 30 min.
33
Vasopressin | Another Name
Pittessin
34
Vasopressin (Pitressin) | Class
Hormone, vasopressor
35
Vasopressin (Pitressin) | Description
Hormone with strong vasopressive and and antidiuretic properties but that may precipitate angina and/or AMI
36
Vasopressin (Pitressin) | Indications
To increase peripheral vascular resistance in arrest (CPR) or to control bleeding from esophageal varices
37
Vasopressin (Pitressin) | Contraindications
PVCs, 1st stage of labor
38
Vasopressin (Pitressin) | Precautions
Epilepsy, migraine, heart failure, angina, vascular disease, hepatic impairment, elderly and children.
39
Vasopressin (Pitressin) | Dose/Route
Cardiac Arrest: 40 units IV | Esophogeal Varices: 0.2-0.4 units/min IV drip
40
Eptifibatide | Another Name
Integrilin
41
Eptifibatide (Integrilin) | Class
Glycoprotein IIb/IIIa inhibitor, platelet aggregation inhibitor
42
Eptifibatide (Integrilin) | Description
Prevents aggregation of platelets by binding to the gylcoprotein IIb/IIIa receptor, preventing the binding of fibrinogen and von Willebrand factors
43
Eptifibatide (Integrilin) | Indications
Unstable angina, and NSTEMI (ACS) being managed medically
44
Eptifibatide (Integrilin) | Contraindication
Any prior intracranial hemorrhage, know malignant intracranial neoplasm, suspected aortic dissection, significant closed head trauma or facial trauma within 3 hours
45
Eptifibatide (Integrilin) | Precautions
Cerebral hemorrhage, pulmonary hemorrhage, hypotension, GI bleeding, intracranial bleeding, anaphylactic shock
46
Eptifibatide (Integrilin) | Dose/Route
Medical management: 180 ug/kg IV bolus over 1-2 minutes followed by 2 ug/kg infusion for 72-96 hours.
47
Bumetanide | Another Name
Bumex
48
Bumex | Another Name
Bumetanide
49
Bumetanide (Bumex) | Class
Loop diuretic
50
Bumetanide (Bumex) | Description
Potent loop diuretic with rapid onset and short duration of action. Inhibits the reabsorption of sodium and chloride in the ascending limb oth the loop of Henle
51
Bumetanide (Bumex) | Indications
Pulmonary edema, CHF
52
Bumetanide (Bumex) | Contraindications
Hypersensitivity to bumetanide or sulfonamides, hypotension, anuria, electrolyte deficiencies, hepatic coma. Use Caution: hepatic cirrhosis, ascites, diabetes, hypersensitivity to furosemide
53
Bumetanide (Bumex) | Dose/Route
0.5-1.0 mg IV slowly over 1-2 min, or IM | Pedi: safety and effectiveness in pediatric is not established