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Flashcards in Miscellaneous Deck (36)
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1
Q

hormone responsible for gallbladder contraction

comes from __ cells of D/J

inc __ secretion, and dec __

A

CCK

I

panc enzyme, gastric emptying

2
Q

secretin promotes ___ sec

released by __

A

bicarb

duodenal S cells

3
Q

Gastrin stimulates __ secretion and __ motility

A

GA. gastric

4
Q

VIP stimulates __

counteracts ___

promotes __

VIPoma WDHA syndrome

A

intestinal water sec

gastrin

bicarb

watery diarrhea, hypokalemia, achlorhydria

5
Q

motilin for ___

A

intestinal motiluty

6
Q

somatostatin inhibited by __

stops release of __/ __

A

low pH

GH/TSH

7
Q

Celiac dz

__ atrophy, crypt __, __ infiltration

presents at __ m w intro of __

Malabsorptive sx S/F/W

A

vilous, hyperplasia, lymphocytic

6-24, gluten

steatorrhea, flatulence, wl

8
Q

newborn esp breastfed needs __/__ supplementing

A

VD/iron

9
Q

pernicious anemia destroys ___

located in __ layer

A

parietal cells

upper gastric

10
Q

glucagonoma sx

2ndary __
exophytic ___

A

DM

rash

11
Q

verapamil blocks __ Ca channels

Lidocaine blocks __ Na channels

A

L type

voltage gated

12
Q

Cells responsible for destroying pathologic cels w dec MHC class 1 expression

do not express CD __/__/__

A

NK cells

CD3/4/8

13
Q

enteropeptidase def sx

F, E, D

A

FtT, Diarrhea, edema

14
Q

MCC of SCID

__ accumulation is toxic to __, resulting in risk of __

secondary form is __

tx SCID via

A

Adenosine deaminsae defic

adenosine, lymphs, infection

X linked

bone marrow transplant

15
Q

myeloperoxidase is an enzyme in __

deficiency leads to __ disorder

A

PMN

myeloperoxidase

16
Q

CGD characterized by infections w __ prodcuign org

hallmark test

deficient in __

A

catalase

nitroblue tetrazolium

NADPH oxidase

17
Q

Panc secretions compared to plasma

Na/K

Bicarb

Cl

A

normal

higher

lowerr

18
Q

Postprandial alkaline tide inc plasma __ and dec plasma ___

A

bicarb, Cl

19
Q

Peptide released by intestines to conteract cephalic/gastric secretion

inhibits __ release from ECL cells

A

Peptide YY

histamine

20
Q

MD has possible for ___ tissues

gastric prodxn can lead to __ formation

A

gastric/panc/colon/endometrial

ulcer

21
Q

XLA is disorder of ___, dec mature __ prodxn

predisposed to __ and __ infections

A

BTK, b cell

LRI giardia

22
Q

host defnese of mycobacterial infections requires interactions of __/__

macrophages infected w mycobacteria produce ___ to stimulate T cells/NK cells to release ___

useful against ___

A

macros/T cells

IL12, INFG

viruses/

23
Q

C3 deficiency leads to infections w __ bacteria

A

encapsulated

24
Q

Neg regulation of lac operon

repressor protien binds __

positive regulation of lac operon as __ binds upstream

A

operator

cAMP-CAP

25
Q

Giardia trophozoite appearance __ shaped w 2 nuclei

mechanism to protect include __ and __

A

owl

IgA, CD4 T cells

26
Q

bilateral CN8 assc w __

A

NF2

27
Q

muscles, CT, bone, cartilege, CV system, lymphatics, genitalia, kidney/AC urethra are __ derived

A

mesoderm

28
Q

GI tract, liver, pancreas, lungs, thymus, PT/Thyroid, middle ear, bladder/urethra are __ derived

A

endoderm

29
Q

rathke pouch, lens/cornea, inner ear, olfacotyr system, epidermis, salivary/mammary glands are ___ derived

A

surface ectoderm

30
Q

Brain/spinal cord, PP, pineal gland, retina are ____ derived

A

neural tube

31
Q

ganglia, schwann cells, pia/arachnoid mater, branchial arches, skull, adnreal medulla are __ derived

A

nerual crest

32
Q

__ is mesoderm derived

derivative is __

A

notochord

nucleus pulposus

33
Q

__ repair is responsible for non bulky DNA alteration

such as depurination, alkylation, oxidation, deamination

excess consumption of __ promotes deamination of CAG

A

BER

nitrates

34
Q

__ cleaves 5’ end of AP site, __ completes extraction, __ fills in gap, nick sealed by ___

A

endonuclease, lyase, DNA poly, ligase

35
Q

__/__ panc buds fuse in __ w of fetal life

proximal part of __ panc bud degenerates, remaineder fuses w ventral duct to form ___

A

ventral/dorsal

dorsal, main panc duct

36
Q

Pancreatic Divisum – when V/D panc buds dont fuse, secretions drained by __

dominant dorsal duct (santorini) drains into __ via minor papilla and drains __ of sec of pancras

smaller ventral duct (whirschprung) opens into ___ and drains base of head/UP

pancreas divisum is __ but inc risk for ___

A

2 separate systems

duodenum, majority

major papilla

asx, pancreatitis