Mitosis And Meiosis Flashcards

(35 cards)

1
Q

What is a p arm?

A

Short arm of chromatid

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2
Q

What is the q arm?

A

Long arm of chromatid

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3
Q

What is a telomere?

A

Repeated sequences at each end of a chromosome or chromatid

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4
Q

What is a centromere?

A

Repetitive sequence that links sister chromatids

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5
Q

What are the positions of centromeres called?

A

Metacentric- middle
Submetacentric
Afrocentric
Telcentric- top

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6
Q

How are chromosomes grouped?

A

According to size and shaped

In groups A-G

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7
Q

What is mitosis?

A

Cell division in somatic cells

Produces two identical daughter cells

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8
Q

What tissues is mitosis necessary for?

A

Epidermis
Mucosae
Bone marrow
Spermatogonia

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9
Q

What occurs in prophase?

A

Spindle fibres appear
chromosomes condense
Nuclear membrane breaks down

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10
Q

What occurs in prometaphase?

A

Spindle fibres attach to chromosomes

Chromosomes condense

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11
Q

What happens in metaphase?

A

Chromosomes align at the equator

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12
Q

What happens at anaphase?

A

Centromeres divide

Sister chromatids move to opposite poles

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13
Q

What happens in telophase?

A

Nuclear membrane reforms
Spindle fibres disappear
Chromosomes decondense

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14
Q

What happens in cytokinesis?

A

Cytoplasm divides

2 genetically identical daughter cells form

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15
Q

What are alleles?

A

Different forms of the same gene

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16
Q

Where are chromosomes during interphase?

A

Chromosome territories

17
Q

What alleles do sister chromosomes have?

18
Q

What is meiosis?

A
Cell division for germ line cells 
Produces 4 non-identical cells 
Haploid
One round of replication and two rounds of division 
Egg and sperm produced
19
Q

What occurs in prophase I?

A

Nuclear membrane breaks down
Chromosomes condense
Crossing over occurs

20
Q

What occurs in metaphase I?

A

Pairs of homologous chromosomes move to the equator of the cell

21
Q

What occurs in Anaphase I?

A

Homologous chromosomes move to opposite poles of the cell

22
Q

What occurs in telophase I?

A

Chromosomes gather at poles of the cell

23
Q

What occurs in prophase II?

A

New spindle forms

24
Q

What occurs in metaphase II?

A

Chromosomes line up at the equator

25
What happens in anaphase II?
Centromeres divide and chromatids move to opposite poles of the cell
26
What happens in telophase II?
Nuclear envelope reforms
27
How does genetic diversity occur?
Random assortment of chromosomes | Crossing over of genetic material
28
What is spermatogenesis?
Cell division to produce male gametes 1 cell (spermatocyte)- 4 sperm Takes around 60 days
29
What is oogenesis?
Cell division to produce female gametes 1 cell (oocyte) - 1 egg and 3 polar bodies Takes 12-50 years
30
What are the consequences of missegregation in meiosis?
Third of miscarriages Infertility Mental retardation
31
What is non-dysfunction at anaphase?
Where the incorrect number of chromosomes is moved to each pole 1 cell gets 2 chromosomes 1 cell gets 0 chromosomes Leads to aneuploidy
32
What is the format to describe a karyotype?
Chromosome number, sex complement and structural changes separated by commas E.g. 47, XY, +21 Male with trisomy 21
33
What does mitotic dysfunction in first post zygote can division lead to?
One with less chromosomes Usually lost unless involved X
34
If non disjunction occurs in later cell divisions
Leads to mosaic karyotype
35
What is mosaicism?
Presence of two or more cell lines in an individual