Mitosis & Meiosis Flashcards

where cells multiply by dividing (52 cards)

1
Q

mitosis

A

asexual reproduction
1 cell (2n) –> 2
2 (2n)
to = two cells

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2
Q

meiosis

A

sexual reproduction
2n –> 4 cells (n)
sperm, eggs
four vowels = 4 cells
2 rounds of cell division

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3
Q

diploid

A

2n = 46
n = 23
human

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4
Q

haploid

A

1

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5
Q

human life cycle

A

man & woman
- man - meiosis , woman - meiosis
- fertilization - zygote
- zygote - mitosis
- baby (2n) - mitosis

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6
Q

cell cycle

A

Interphase (90%):
G1, S-phase, G2
M phase(10%): mitosis

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7
Q

G1

A

first part of interphase
organelles begin to double in number

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8
Q

S phase

A

2nd part of interphase
replication of DNA

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9
Q

G2

A

3rd part of interphase
synthesis of proteins, prep for cell division

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10
Q

interphase

A

centrosomes, chromatin, nuclear envelope, plasma membrane

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11
Q

prophase

A

DNA condenses like yarn, nucleus disappears

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12
Q

metaphase

A

‘middle phase’
metaphase plate forms
chromosomes are aligned
at the equator of the spindle

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13
Q

anaphase

A

separate sister chromatids, they go to the opposite sides of the cell

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14
Q

telophase

A

opposite of prophase
nuclei form and spindle disappears

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15
Q

cytokinesis

A

cell moves apart, cleavage furrow, creating two daughter cells

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16
Q

cancer

A

uncontrolled cell growth
90% of cancers are caused by epithelial cells
- avoids checkpoints in cell cycle

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17
Q

contact dependent

A

cells will continue to grow until an area is covered, then stop - cancer cells do not have contact dependency

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18
Q

tumor

A

cancer cells pile up on top of each other creating
(benign is fine)

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19
Q

anchorage dependent

A

cells will stay attached / grounded to surroundings
cancer - loss of anchorage dependency

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20
Q

metastasis/ metastatic cancer

A

movement of unanchoraged tumors

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21
Q

apotosis

A

cell suicide - won’t happen in cancer/ bad cases of cancer

22
Q

G0 cells

A

cells that will not regenerate when killed
nerve cells, cardiac, skeletal

23
Q

stage 1 cancer

A

loss of contact dependency
benign tumor at this point
take a sample to see if its self contained

24
Q

stage 2 cancer

A

cells spread and invade neighboring tissue
typically rough edged

25
stage 3 cancer
loss of anchorage dependency, can now migrate, has it metatisized? check lymphatic vessels
26
stage 4 cancer
small percentage of cancer cells may survive and establish a new tumor in another part of the body - based on other people who have had this, estimate for how long you will live
27
chemotheraphy + radiation
kill rapidly dividing cells nausea hair loss
28
2n 46 chromosomes n 23 pairs
meiosis two rounds of cell division 1 cell diploid (2n) --> meiosis --> 4 cells haploid (n) --> sperm + eggs
29
interphase before meiosis
pair of homologous chromosomes in diploid parent cell (g1) chromosomes duplicate (s phase) duplicated pair of homologous chromosomes (g2)
30
centromere
holds the two sister chromatids together (forms a chromosome)
31
meiosis I
homologous chromosomes separate (now they are haploid)
32
meiosis II
sister chromatids are split (now there are four singular chromatids)
33
prophase I
homologous pairs come together exchange segments (crossing over - chiasima)
34
metaphase I
pairs of homologous chromosomes line up
35
anaphase I
separate the pairs of homologous chromosomes
36
telophase/cytokinesis I
cells divide (two haploid cells form - chromosomes are still doubled)
37
prophase II
pairs together tetrad (two pairs of sisters)
38
metaphase II
align
39
anaphase II
separate
40
telophase / cytokinesis II
creation of four new cells, haploid daughter cells, containing single chromosomes
41
human gametogenesis
making sex cells
42
spermatogenesis
making sperm 1 --> 2 --> 4 (spermatids) spermiation - remodel the spermatid to make sperm
43
oogenesis
making an egg excess DNA (polar body)
44
fertilization
zygote (finish meiosis II) - fertilized egg (diploid)
45
mutations of chromosomes
nondisjunction - chromosomes do not split up correctly
46
23 homologous pairs
1 - 22 autosomes 23rd pair - sex chromosomes
47
down's syndrome
2n +1 (trisomy)
48
cridochat
2n - 1 (monosomy)
49
Y chromosome
sex determining region of the chromosome
50
SRY gene
make a male gene
51
X0
Turner's syndrome - no secondary sex characteristics - infertile - 1 gonad, not specified, no internal reproductive system
52
XXY
Klinelfelter's syndrome - poor secondary sex characteristics infertile