Mobility Pharmacology

Question 1

RA Medication Classifications

Answer 1

NSAIDS
Corticosteroids
DMARDs

Question 2

DMARDs Classifications

Answer 2

Methotrexate
Sulfasalazine
Biologic DMARDs

Question 3

Methods used

Answer 3

RA treatment:
Rapid anti-inflammatory effects
Bone marrow suppression and hepatotoxicity
Jbianand knitting Frequent lab monitoring of CBC and chem panels bs

Question 4

Sulfasalazine

Answer 4

RA treatment:

Milder effects and safer

Question 5

Biologic DMARDs

Answer 5

RA Treatment:
Aimed at interrupting the progression of the disease
Entanercept (Enbrel)
↑ risk of infection

Question 6

4 main classifications to treat osteoporosis

Answer 6

SERMs
Biphosphonates
Calcitonin
Calcium supplements

Question 7

SERMs

Answer 7

Osteoporosis treatment:

Mimic estrogen by ↓
bone absorption w/o stimulating tissues of breast or uterus

Raloxophene (Evista)

Question 8

SE of SERMs

Answer 8

Osteoporosis treatment:

Leg cramps
Hot flashes
Blood clots

Question 9

Biphosphonates

Answer 9

Osteoporosis treatment:

Alendronate (Fosamax) 1x/week
Ibandronate (Boniva) 1x/month

Question 10

SE of biphosphonates

Answer 10

Osteoporosis treatment:

Weight loss
anorexia
gastritis

Question 11

Calcitonin

Answer 11

Osteoporosis treatment:

Inhibits bone resorption and is secreted by the thyroid gland.

Salmon calcitonin (Calcimar)

Can’t be orally absorbed. Stopped at some point in GI

Question 12

OA Medication Classifications

Answer 12

Salicylates
Topical analgesics like capsaicin cream (Zostrix)
NSAIDs

Steroids are a second step
Depo-Medrol

Question 13

Goal of treatment of Myasthenia Gravis

Answer 13

Increase amount of acetylcholine for muscle contraction

Decrease muscle weakness, fatigue

Question 14

Chronic Gout Medications

Answer 14

Xanthine oxidase inhibitor (Allupurinol)
Uricosuric probenecid 
Febuxostat
Corticosteroids
ACTH

Question 15

Acute Gout Medications

Answer 15

Colchine
NSAIDs
corticosteroids

Question 16

SE of Colchicine

Answer 16

muscle pain / weakness
numbness/tingly in fingers or toes
Severe vomiting
Diarrhea
fever
chills
body aches
flu symptoms

Question 17

Drug therapy for lupus

Answer 17

NSAIDs
Antimalarials
Corticosteroids
Immunosuppressives
Immunomodulators

Question 18

Alpha 1

Answer 18

Smooth muscle contraction

Question 19

Beta 1

Answer 19

↑ HR

Question 20

Beta 2

Answer 20

bronchodilation

Question 21

Beta 3

Answer 21

Site of lipolysis

Question 22

Use spacers with

Answer 22

MDIs

Question 23

2 categories of respiratory medications

Answer 23

BAM

SLM

Question 24

BAM

Answer 24

bronchodilators

beta 2 agonists “-terol”
Anticholinergic agents “-pium”
Methylxanthines “-phylline”

Question 25

SLM

Answer 25

Anti-inflammatory agents Steroids "-sone" Leukotrienes "-lukast" Mast Cell Stabilizers "-crom"

Question 26

Beta 2 agonist medications

Answer 26

Albuterol Solumedrol You'll see ↑ HR and bronchodilation

Question 27

Anticholinergic Agent medicaitons

Answer 27

Ipratropium Bring ↓ mucus prod. in bronchi and bronchioles

Question 28

Methylxanthines

Answer 28

Theophylline Causes sympathetic response ↑ HR, opens the lungs

Question 29

Steroids/Corticosteroids Medications

Answer 29

Prednisone Methylprednisone Prednisolone Causes sympathetic response ↑ HR and opens lungs Must wean off these

Question 30

Leukotrienes

Answer 30

Singulair, Montelukast "Luke likes to sing" Cause bronchi and bronchioles to relax

Question 31

Mast cell stabilizer medications

Answer 31

Cromolyn "mass of chrome" Reduce swelling and inflammation

Question 32

Bronchodilator adverse effects

Answer 32

``` tachycardia and palpitations headache tremor restlessness nervousness ``` Toxicity r/t theophyline

Question 33

Adverse effects of inhaled corticosteroids

Answer 33

``` candidiasis of mouth/throat hoarseness slow growth in children adrenal suppression long-term ↑ risk of cataracts ```

Question 34

Adverse effects of leukotriene receptor antagonists

Answer 34

restlessness headache upper resp. tract infection

Question 35

Which works quickly to relax smooth bronchial muscle resulting in widened airway? First in line for acute attack

Answer 35

Albuterol

Question 36

Antihistamines act on which receptor

Answer 36

H1 receptor agonist Inhibits smooth muscle constriction in BV, respiratory, and GI tracts Decrease capillary permeability

Question 37

What are antitussives

Answer 37

Drugs that suppress cough

Question 38

What are expectorants?

Answer 38

render the cough more productive by stimulating the flow of resp. tract secretions

Question 39

Mucolytics

Answer 39

react directly with mucus to make it more watery. This makes cough more productive Acetylcysteine

Question 40

Nasal Decongestants

Answer 40

Stimulate alpha1-adrenergic receptors on nasal BV | Causes vasoconstriction causing shrinkage of swollen membranes

Question 41

Intranasal Corticosteroids

Answer 41

Have inflammatory actions | Prevent or suppress all major symptoms of allergic rhinitis

Question 42

Intranasal Corticosteroids Medications

Answer 42

fluticasone (Flonase) | mometasone (Nasonex)

Question 43

Intranasal corticosteroids suffix

Answer 43

"-sone"

Question 44

What is the medication central to symptom management for COPD?

Answer 44

bronchodilator medications Inhaled therapy preferred

Question 45

What are more effective, short or long acting bronchodilators?

Answer 45

Long-acting inhaled bronchodilators

Question 46

Side effect of Rifampin (TB medication)

Answer 46

Orange colored body secretions

Question 47

TB medication

Answer 47

Rifampin

Question 48

steroid suffix

Answer 48

"-sone"