Mode Of Action Transfusion Therapy Flashcards
Increases oxygen- carrying capacity
Increases blood volume
Whole Blood
Increases oxygen- carrying capacity
RBC (Adenine-saline added)
RBC pheresis
Deglycerolization removes plasma proteins.
Risk of allergic and febrile reactions reduced; increases oxygen-carrying capacity
RBC deglycerolized
Leukocyte reduction is achieved by filtration: (1) soon after collection (prestorage) or (2) after varying periods of storage in the laboratory.
Red blood cells: leukocyte-reduced
Improves hemostasis
Apheresis platelets may be HLA (or other antigen) selected.
Platelets / apheresis
Platelets leukocytes reduced/apheresis platelets leukocytes reduced
Increases the level of granulocytes to phagocytize and kill bacterial and fungal infections
Apheresis Granulocytes
Coagulation support for life-threatening trauma, hemorrhages
Plasma (liquid)
Provides fibrinogen (factor I), factors VIII, XIII, and vWF
Cryoprecipitate pooled/ cryoprecipitated AHF
Source of all coagula- tion proteins and plasma proteins
Fresh-frozen plasma (FFP)
Source of nonlabile plasma proteins
Levels of factor VIII are significantly reduced and levels of factor V and other labile plasma proteins are variable compared with FFP.
PF24
(Plasma frozen within 24 hours after phlebotomy)
Source of nonlabile plasma proteins
Levels of factor V, factor VIII, and protein S are significantly reduced, and levels of other labile plasma proteins are variable compared with FFP.
PF24RT24
(Plasma frozen within 24 hours after phlebotomy held at room temperature up to 24 hours after phlebotomy)
Source of plasma proteins and contains stable coagulation factors (factor II, fibrinogen), similar clinically to the levels found in FFP; other factors are variable, being reduced in levels that change over time
Thawed plasma
Plasma protein replacement for plasma exchange in TTP; this product contains variable levels of albumin, ADAMTS13, and factors II, V, VII, IX, X, and XI.
Thawed plasma, cryo- precipitate reduced
