Module 1 MiniModule 5: Topical Therapy Flashcards
(50 cards)
What form of topical treatment is the following describing?
- Mechanical effect will always be beneficial (remove skin debris, allergens)
- Chose according to skin condition
- Can be applied in a limited area (chin, paws)
Shampooing
What form of topical treatment is the following describing?
- Is better if you shave the affected area for easy application
- Apply products once to twice daily until resolution
- Maintenance frequency based on each case
Ointments-creams-lotions-wipes
- avoid the patient from licking/chewing the area for at least 1/2 hour after applying
What are the “big categories” for topical therapy?
- Keratoseborrheic disorders
- Infectious dermatitis
- Allergic dermatitis
- Otits externa
The following clinical signs are from:
- Scaling
- Oiliness-rancid smell
- Recurrent infections
Keratinization disorders
Products often used for Keratinization disorders:
- Help remove excess of scale either by increasing desquamation or by reducing intercellular cohesion
Keratolytic
- allergic, scabies
Definition:
- shedding of the outer layers of the skin
- your skin’s way of recovering or healing from some type of damage
desquamation
Products often used for Keratinization disorders:
- Regulate skin cell proliferation - a cytostatic effect is probably exerted on basal cells, reducing their rate of division (prevents build-up)
Keratoplastic
- good for genetic skin conditions, chronic
Products often used for Keratinization disorders:
- Reduce sebum, degreasing
Antiseborrheic
What active ingredient is this describing?
- Keratolytic & keratoplastic
- Mild follicular flushing
- Not a good Degreaser
Sulphur
What active ingredient is this describing?
- Keratolytic (remove excess build-up)
- Act synergistically
- Usually, come together
Salicylic Acid
What active ingredient is this describing?
- Keratolytic
- Follicular flushing (Demodex)
- Degreasing - “seborrhea oleosa”
- Can bleach hair, cloth, furniture
Benzoyl peroxide 2.5 - 3%
What active ingredient is this describing?
- Keratolytic & Keratoplastic
- Very degreasing - soborrhea oleosa
- Not a veterinary product
- May be toxic in CATS
Selenium sulfide
What active ingredient is this describing?
- Keratolytic
- apply twice a day until resolution of the clinical signs, then decrease frequency to once day or less
Salicylic Acid Gel 6.6%
What active ingredient is this describing?
- Restructure stratum corneum
- Control sebum production
- Control microbial flora
- Moisturizes
Ceramides/Fatty acids
- HyLyt bath oil (Bayer)
- fatty acids - DermAllay spray (Dechra)
- oatmeal, safflower oil, ceramide
What are these?
Moisturizers
Bacterial Infections:
What is the most common pathogen?
Staphylococcus pseudintermedius
Bacterial Infections:
What is the most common clinical presentation?
superficial pyoderma
Antibacterial Therapy:
- Chlorhexidine
- Benzoyl Peroxide (anti-bacterial effects)
- Ethyl Lactate (anti-bacterial effects)
- Sodium hypochlorite (bleach)
These are found in the form of what?
Shampoo/mousse/wipes
Antibacterial Therapy:
- Silver sulfadianzine
- Medical-grade honey
- Mupirocin (anti-bacterial)
These are found in the form of what?
Ointment/Cream
Antifungal Therapy:
Name the Azoles
- Miconazole
- Ketoconazole
- Climbazol
Antifungal Therapy:
Name the Allylamines
- Terbinafine
- Naftifine
Acts by damaging the outer cell wall, causing the bacteria to become more permeable to the antimicrobial agents that act intracellularly
Tromethamine-ethylenediaminetetraacetic acid (TrisEDTA)
Tris-EDTA is an effective _____________ agent in vitro
antibiofilm
(T/F) It has been shown to enhance the efficacy of marbofloxacin and gentamicin against Pseudomonas aeruginosa
True
