Module 13: Fluids and Electrolytes Alterations Flashcards
Enumerate the fluid content among infants and adults.
(A) Infant: 70 to 80%
(B) Adult Female : 50 to 60%
(C) Adult Male: 50 to 70%
(D) Older Adult: 45 to 55%
How much extracellular fluid (ICF) is in our body?
1/3 of Fluid in Blood or Plasma and Interstitial Space
How much intracellular fluid (ICF) is in our body?
2/3 of Fluid within Cells
(This is important to note because when children suffer from dehydration, their ICF is easily depleted - HIGHER MORTALITY RATE).
What is the difference between dehydration and hypovolemia?
(A) Hypovolemia: Both intracellular and extracellular fluid are depleted.
(B) Dehydration: Most of the intracellular fluid and plasma is depleted.
What are the two types of extracellular fluid?
(A) Interstitial: Fluid in between the cells (lymph)
(B) Intravascular: Fluid within the blood vessels.
This is the fluid in small and specialized cavities (synovium, CSF, pleura, and peritoneum).
Transcellular Fluid
This is the diffusion of a water or solvent molecule through a selective permeable membrane (eg cell membrane).
OSMOSIS
How does water move in osmosis?
From low solute concentration to a high solute concentration.
What is another term for oncotic pressure?
COLLOIDAL OSMOTIC PRESSURE dependent on BLOOD PRESSURE and PROTEINS
What exerts oncotic pressure in the blood?
Proteins (mainly albumin)
What is the normal oncotic pressure at the capillary level?
25 mmHg
What happens when oncotic pressure decreases?
A decreased in oncotic pressure or low protein levels within the blood would cause fluid to move from the intravascular space into the interstitial space.
What does Starling’s Law of Fluids explain?
The movement of fluid across capillary membranes based on hydrostatic and oncotic pressures.
What exerts hydrostatic pressure in the capillaries?
The pumping action of the heart; EXPRESSED AS BLOOD PRESSURE.
(ARTERIAL END: 40 mmHg; VENOUS END: 10 mmHg)
What exerts oncotic pressure in the capillaries?
Blood proteins (mainly albumin; EXPRESSED AS Pi (π), not to be confused with the math constant 3.1416.
What happens when hydrostatic pressure exceeds oncotic pressure?
Fluid moves out of the capillaries into the interstitial space.
What happens when oncotic pressure exceeds hydrostatic pressure?
Fluid moves into the capillaries from the interstitial space.
What is first spacing in fluid distribution?
Normal distribution of fluid in intracellular fluid (ICF) and extracellular fluid (ECF)
What is second spacing in fluid distribution?
Abnormal accumulation of fluid in the interstitial space, such as edema
What is third spacing in fluid distribution?
Fluid accumulates in a portion of the body where it is trapped and unavailable for functional use
Give examples of third spacing.
Ascites, fluid sequestration in the abdomen, and edema associated with burns
A solution with a lower concentration of solutes and a higher concentration of water compared to inside the cell
HYPOTONIC SOLUTION
The ability of a solution to change the shape and size of cells by altering water movement across the cell membrane
TONICITY (CONCENTRATION OF SOLUTES)
What kind of pressure does a hypotonic solution have?
Less osmotic pressure or osmolalality.