MODULE 2

Question 1

Consider drugs in body to be in DYNAMIC STATE

Answer 1

Pharmacokinetic model

Question 2

Important tool for analyzing drug movement quantitatively

Answer 2

Calculus

Question 3

Used to relate the concentrations of drugs in various body organs

Answer 3

Differential equation

Question 4

Frequently used to model the cumulative therapeutic or toxic responses of drugs

Answer 4

Integrated equation

Question 5

Branch of calculus that involves finding the rate at which a variable
quantity is changing

Answer 5

Differential calculus

Question 6

Reverse of differentiation

Answer 6

Integration

Question 7

Summing up of small individual pieces under the graph

Answer 7

Integration process

Question 8

Sum of individual areas under the graph

Answer 8

Definite Integral

Question 9

Numerical method used in pcok to calculate AUC

Answer 9

Trapezoidal rule

Question 10

Important method of visualizing relationship between variables.

Answer 10

Graph

Question 11

Placed horizontal line or in abscissa (x axis)

Answer 11

Independent variable

Question 12

Placed vertically or in ordinate (y axis)

Answer 12

Dependent variable

Question 13

An independent variable plotted on abscissa

Answer 13

Time

Question 14

Arranged vertically or logarithmically from left to right or bottom to top.

Answer 14

Values

Question 15

An dependent variable plotted on the ordinate.

Answer 15

Drug concentration

Question 16

2 types of graph

Answer 16

Cartesian or Rectangular coordinates
Semilogarithmic graph

Question 17

Allows placement of data at logarithmic intervals

Answer 17

Semilogarithmic graph

Question 18

When using this, relationship is not confined to isolated points.

Answer 18

Curve fitting

Question 19

Best describes the hypothesis and must satisfactorily fit experimental or observed data.

Answer 19

Emperical Equation

Question 20

Not always linearly related

Answer 20

Physiologic Variables

Question 21

Very useful for accurately predicting values for there are no experimental observations.

Answer 21

Straight line

Question 22

2 mathematical function that is related to each other.

Answer 22

Exponential and Logarithmic function

Question 23

Determines degree of ionization of drug

Answer 23

PH of Biological drug

Question 24

Process is always constant and independent

Answer 24

First order kinetic

Question 25

assumes a linear or straight-line function between data points

Answer 25

Trapezoidal rule

Question 26

Assumes a linear or straight line function

Answer 26

Trapezoidal rule

Question 27

Independent in drug concentration

Answer 27

Zero order kinetics

Question 28

Half life is not constant

Answer 28

Zero order kinetics

Question 29

Dependent on drug concentration

Answer 29

First order kinetics

Question 30

Half life is always constant

Answer 30

First order kinetics