Module 4 Flashcards

1
Q

what the drug does to the body

A

pharmacodynamics

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2
Q

what the body does to the drug

A

pharmacokinetics

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3
Q

Pharmacokinetics includes:

A

absorption
distribution
metabolism
excretion

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4
Q

pharmacodynamics includes:

A

receptors
ion channels
enzymes
carrier proteins

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5
Q

method and rate at which drugs leave site of administration

A

absorption
(small intestine or liver)

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6
Q

after the drug leaves the systemic circulation and enters the cells

A

distribution

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7
Q

why elderly may experience toxicity

A

high fat, low protein

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8
Q

steady state

A

drug eliminated is equal to dose administered

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9
Q

half life

A

time to clear 50% of drug from plasma

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10
Q

elimination

A

takes 5 half lives to completely eliminate drug

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11
Q

Long-acting injectable pharmacokinetics

A

rate of absorption is slower than elimination.

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12
Q

20% of Asians have _____

A

reduced activity of 2C19 enzyme

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13
Q

Common Inhibitors

A

bupropion
clomipramine
cimetidine
SSRIs

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14
Q

Common inhibitors (2)

A

fluoroquinolones
clarithromycin
grapefruit juice
ketoconazole
nefazodone

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15
Q

common inducers

A

carbamazepine
st. john’s wort
phenytoin
phenobarbital
tobacco

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16
Q

relative dose required to achieve certain effects

A

potency

17
Q

ion channel excitatory response

A

depolarization
(sodium and calcium in)

18
Q

ion channel inhibitory response

A

repolarization
(chloride in, potassium out)

19
Q

low therapeutic index

A

lithium (0.5-1.2)

20
Q

CBT

A

changing beliefs, cognitive distortions, conceptions

21
Q

EMDR

A

alternate tapping, sounds, lights
desensitization, installation, body scan

22
Q

takes memory of trauma from active part of brain to inactive part of brain

A

EMDR

23
Q

family systems therapy

A

Boundary issues -
-diffuse, enmeshmet
- clearly defined
rigid or inflexible

24
Q

solution focused therapy

A

miracle questions
exception finding questions
scaling questions

25
Q

Genogram: Structural mapping uses symbols to represent:

A

over-involvement
conflict
coalitions