Module 6 Flashcards
(93 cards)
Define resistance training
the act of repeated voluntary muscle contractions against a greater resistance (than typically found in daily life)
What factors are in play for sarcomere decline
- dysfunction in cells/mitochondria
- impaired vascular ability
- insufficient energy
- illness
- insulin resistance
What kind of adaptations do we see in resistance training?
- Strength - increases by a lot
- hypertrophy - increases by a bit
- neural - increases by a bit, mostly in the first 12 weeks
what plays a big role in muscle strength?
Learning factors/neural connections! strength improvement can occur with repeated testing over 5 attempts
define hypertrophy
skeletal muscle fibre growth
What processes are necessary for hypertrophy?
- metabolic stress
- mechanical tension
- muscle damage
What is meant by muscle damage
- z line streaming (obvious when looking at many fibres, which appears as smearing)
- plasma CK/myoglobin
- Pain (Delayed Onset Muscle Soreness)
- force loss
what adaptations must occur to initiate hypertrophy
- protein synthesis
- proliferation
What processes are covered under metabolic stress
- altered myokine production
- cellular swelling
- elevated hormone release
- increased fibre recruitment
- Reactive Oxygen Species production
define mechanical tension
: state of stiffness in muscle that can be sensed by sarcolemma
what is phosphatidic acid
: a type of phospholipid that is important for biosynthesis
why is phosphatidic acid important
- increases protein synthesis
- activates down stream signal (MAPK or mTOR?)
how are proteins formed?
collection of amino acids binding together
Describe the relationship between protein synthesis and balance
balance is pretty level, synthesis goes up and down. protein is made at the bottom of the curves?
How does protein synthesis change with resistance exercise
the variations are greater in the fed state and decline less in the fasted state
draw the graph for protein balance, both at rest and with resistance exercise
How can we measure muscle protein synthesis
Biopsy!
describe the steps behind taking a muscle biopsy
- infuse a ‘heavy’ amino acid
- take a piece of muscle
- examine how much of the heavy amino acid was incorporated
what is the term for the rate of muscle protein built per hour
fractional synthetic rate (%/hr)
what is a satellite cell
stem cell found in muscle important for growth, repair and function
what determines if a muscle is a high responder or low responder
i think the amount of satellite cells or capillaries it has? low responder has a lower amount and higher CT
How do satellite cells affect the body
maintenance and gives nuclei away
How does the body respond to resistance training
- HR
- muscle size increases 20-30%
- ribosome content increases
- MPS after exercise increases
- increase satellite cell, capillary number etc
how do men and women differ in resistance training adaptations
males and females respond similarly to hypertrophy, but males have much greater absolute muscle size increase
relative, male and female are similar