Money

Question 1

DOC Brucellosis

Answer 1

• • Doxycycline

Question 2

Cephalosporin -Not for neonates: Ca2+ crystals in lungs and biliary slugging

Answer 2

• • Ceftriaxone

Question 3

Aminoglycosides are effective against what organisms?

Answer 3

—Effective against E.Coli, Klebsiella, P. Areuginosa**, Acinobacter (gram –ve)

Question 4

DOC ACTIVE TB disease in Pregnant Women

Answer 4

–INH, Rifampin, and Ethambutol for 9 mos

don’t use Streptomycin

Question 5

DOC in invasive pulmonary or extra pulmonary infections caused by Candida Spp.

Answer 5

• • Voriconazole (Vfend)

Question 6

DOC Plague [Yersinia pestis] (gram Neg Coccobacillus)

Answer 6

Streptomycin IV or Gentamicin

—-Alternatives : Doxycycline or ciprofloxacin

Question 7

DOC to treat N. gonorrhea infections of the cervix, urethra, and rectum

Answer 7

• • Ceftriaxone (Rocephin) IV

Question 8

First line agent for animal bites

Answer 8

• • Amoxicillin/Clavulanate (Augmentin) PO

Question 9

Drug of choice to treat ANTHRAX (Inhalation, Cutaneous and GI)

Answer 9

• • Ciprofloxacin or Doxycycline

Question 10

DOC for tx TB Infection 4 mos

Answer 10

• • Rifampin

Question 11

Preferred for SEVERE Clostridium Difficile [C. Difficile] infection

Answer 11

• • Vancomycin PO x 10-14d

Question 12

DOC for Tx for PCN sensitive Gangrene [C. perfringen]

Answer 12

• • Natural Penicillins -1st Generation

Question 13

DOC for Onychomycosis

Answer 13

• • Terbinafine (Lamisil) or Itraconazole PO; toenails 12 wk, fingernail 6 wk

Question 14

DOCs used in Tx Active TB Treatment in Pregnancy

Answer 14

• • Isoniazid [INH], Rifampin, and Ethambutol for 9 months

Question 15

DOC for Mycobacterium Avium Complex (MAC)

Answer 15

• • Rifabutin

Question 16

Multidrug Resistant Organisms (MDRO)

Answer 16

• Methicillin resistant Staphylococcus aureus (MRSA)
• Vancomycin resistant Enterococci (VRE)
• Extended Spectrum beta-lactamase (ESBL)
• Klebsiella pneumoniae carbapenemase (KPC)

Question 17

Preferred for MILD - MODERATE Clostridium Difficile [C. Difficile] infection

Answer 17

• • Metronidazole x 10-14d

Question 18

DOC for treatment of UTI in PREGNANCY

Answer 18

May use x 7 days :

• -Amoxicillin
• -Nitrofurantoin [up to 37th week]
• -Cephalexin

Question 19

DOC/TX Uncomplicated CYSTITIS

Answer 19

• -Triemethoprim (TMP)/SMX x 3 days;
• -Nitrofurantoin x 5 days OR
• -Fosfomycin x 1 dose

Question 20

Cephalosporins Crosses BBB

Answer 20

-Ceftriaxone, cefotaxime, and ceftazidime

Question 21

DOC Tularemia [Francisella tularensis]

Answer 21

• • DOC : Streptomycin IV or Gentamicin

- —Alternatives : Doxycycline or ciprofloxacin

Question 22

DOC for Impetigo

Answer 22

• • Mupirocin (Bactroban)-because of MRSA coverage

Question 23

DOC for preferred 3 months therapy of LTBI in ONLY person 12 years or older

Answer 23

DOC for preferred 3 months therapy of LTBI in ONLY person 12 years or older
- - Isoniazid and Rifapentine

Question 24

TX M. leprae [aka Hansen’s disease]

Answer 24

Dapsone + Rifampin x 6-12 mo

add Cofazimine if severe and take regimen 12-24 mo

Question 25

DOC in treatment of the combination for M. tuberculosis, M. leprae and M. kansasii antigens

Answer 25

- - Rifampin

Question 26

DOC Fungal Pneumonia that does not respond to antifungals

Answer 26

- Sulfamethoxazole-Trimethoprim (Septra)

Question 27

DOC for the treatment of latent TB

Answer 27

- - Isoniazid (INH) | [Must add pyridoxine (B6) to prevent drug-induced central and peripheral neuropathy ]

Question 28

DOC [therapy of choice] preferred for W/o contraindications LTBI in Children 2-11; Adults, HIV Pt & Pregnant Women

Answer 28

- - 9 months: Isoniazid PLUS Pyridoxine/vitamin B6 supplements

Question 29

Human bites DOC

Answer 29

- - Early : Amoxicillin-Clavulanate PO 5D (1st line cat/dog bites) - - Later : Ampicillin/Sulbactam IV Q6H or Cefoxitin 2 grams IV q 8h. - PCN allergic : Clindamycin + either Ciprofloxacin or TMP/SMX

Question 30

DOC used in Prophylaxis against invasive fungal infections in immunocompromised patients

Answer 30

- - Fluconazole (Diflucan)

Question 31

DOC for serious forms of invasive fungal infections

Answer 31

- - Amphotericin B (can be used empirically & prohylactically)

Question 32

DOC for first line treatment (oral) of Onychomycosis (Nail Fungus)

Answer 32

- - Terbinafine or Itraconazole

Question 33

DOC for Trichomonas vaginalis

Answer 33

- - Metronidazole or Tindazole

Question 34

DOC for Tx for *Syphilis* [T. pallidum]

Answer 34

- - Penicillin G Bicillin LA

Question 35

DOC Uncomplicated Vulvovaginal Candidiasis (VVC)

Answer 35

- - Fluconazole 150mg po x 1 [ Ora l Azoles] | ALTERNATIVE : Itraconazole: 200mg po BID x 1 day

Question 36

DOC Q-Fever [Coxiella burnetii]

Answer 36

- - Doxycycline

Question 37

Second line multiple drug therapy used for treatment of M. Tuberculosis [TB]

Answer 37

- Rifabutin - Rifapentine & - Streptomycin (SM)

Question 38

DOC Tinea Versicolor

Answer 38

- - Ketoconazole 2% cream apply once a day for 2 weeks

Question 39

DRUGS CONTRAINDICATED for treatment of UTI in PREGNANCY

Answer 39

- -Fluoroquinolones - -TMP/SMX - -Aminoglycosides - -Tetracyclines

Question 40

Ideal choice for treatment of *mild-moderate* community-acquired-pneumonia [CAP]

Answer 40

MACROLIDES : & ketolides - --Azithromycin - --Erythromycin - --Clarithromycin

Question 41

DOC to eradication of nasal colonization of MRSA

Answer 41

- - Mupirocin (Bactroban)

Question 42

DOC/TX Uncomplicated PYELONEPHRITIS

Answer 42

- -TMP/SMX x 14 days OR | - -Fluoroquinolone x 5-7days

Question 43

DOC for many susceptible fungal infections, including invasive and noninvasive candidiasis and cryptococcal disease &

Answer 43

- - Fluconazole (Diflucan)

Question 44

DOC 1st line option for invasive candidiasis including candidemia

Answer 44

- - Caspofungin (Cancidas)

Question 45

DOC Candida infections in immunocompromised patients

Answer 45

- Fluconazole - Posaconazole - -Anidulafungin (Eraxis) - Refractory cases - -Caspofungin (Cancidas) - Refractory cases

Question 46

DOC vaginal candidiasis

Answer 46

- - Fluconazole

Question 47

DOC in Aspergillus infections

Answer 47

- - Voriconazole (Vfend)

Question 48

Resistant Vulvovaginal Candidiasis (VVC)

Answer 48

--Boric acid 600mg inttra-vaginal capsule x 14d

Question 49

DOC/TX Community Acquired Pneumonia (CAP) with *NO comorbidities*

Answer 49

-- Macrolides : Clarithromycin or Azithromycin or --Doxycycline

Question 50

DOC used in Prophylaxis against of Asperigullos and Candida infections in immunocompromised patients

Answer 50

--Posaconazole

Question 51

Drug of choice for pre/post surgery not involving the abdomen

Answer 51

Cefazolin (Ancef)- used as surgical prophylaxis

Question 52

First line multiple drug therapy used for treatment of M. Tuberculosis [TB]

Answer 52

- Isoniazid (INH) - Rifampin (RIF) - Pyrazinamide (PZA) & - Ethambutol (EMB)

Question 53

DOC 1st line option for Candida prophylaxis in hematopoietic cell transplant recipients

Answer 53

- - Micafungin (Mycamine) | DOC 1st line option for invasive candidiasis

Question 54

LTBI treatment of choice in pregnancy

Answer 54

- - Isoniazid [INH] once daily or twice weekly for 9 months with Pyridoxine supplementation

Question 55

DOC used for Prophylactically or treatment of meningitis caused meningococci or H. influenza

Answer 55

- - Rifampin

Question 56

Cephalosporins drug of choice for meningitis

Answer 56

- - Ceftriaxone