More exchange and transport systems: Digestion and absorption Flashcards

(30 cards)

1
Q

What is digestion

A

The process by which large biological molecules such as carbohydrates, lipids and proteins get hydrolysed into their smaller molecules

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2
Q

Why does digestion occur

A

It occurs so that large biological molecules can be broken down into nutrients, and absorbed into cell membranes - so it can be used for growth and repair

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3
Q

What digestive enzymes catalyses the breakdown of carbohydrates (and state what they catalyse the hydrolysis of)

A
  • Amylase
  • Membrane-bound disaccharidases
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4
Q

How many polysaccharides make up starch (and state the monomers of it)

A
  • Its made of two polysaccharides chains
  • Made of long chains of alpha glucose molecules
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5
Q

How does amylase work (what bonds do they catalyse the hydrolysis of) (what does it produce)

A

Amylase works by catalysing the glycosidic bonds in starch to produce maltose (a disaccharide)

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6
Q

Where is amylose produced

A
  • The salivary glands - which releases it into the mouth
  • The pancreas - which releases it into the small intestine
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7
Q

What are membrane-bound disaccharidases

A

They are enzymes attached to the cell membranes of epithelial cells lining the ileum- breaking down disaccharides into monosaccharides

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8
Q

How do membrane-bound disaccharidases work (what bonds do they catalyse the hydrolysis of) (what does it produce)

A

Membrane-bound disaccharidases works by catalysing the hydrolysis of glycosidic bonds in disaccharides (maltose) to produce alpha glucose (a monosaccharide)

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9
Q

What digestive enzymes catalyses the breakdown of lipids

A

Lipase

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10
Q

What does lipase catalyse the hydrolysis reactions of (and what does it produce)

A

It catalyses the hydrolysis reactions of ester bonds in lipids - breaking them down into some monoglycerides, glycerol and fatty acids

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11
Q

What is emulsification

A

A process which large lipid globules are broken down into several small globules

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12
Q

What substance emulsifies lipids

A

Bile salts

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13
Q

Where are lipases mainly produced

A

The pancreas

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14
Q

Where are bile salts produced

A

The liver

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15
Q

Why is the emulsification of big lipid globules into micelles important

A

The formation of small droplets increases the surface area of lipids that available for the lipases to work on enabling faster hydrolysis

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16
Q

Describe the process of lipid digestion in order

A
  • Lipids are coated in bile salts to create an emulsion
  • Lipase hydrolyses lipids into glycerol and fatty acids (sometimes monoglycerides)
  • Micelles are formed of the fatty acids, glycerol, monoglycerides and bile salts
  • Micelles release the monoglycerides, fatty acids and glycerol and due to their non-polar nature (lipid soluble), they diffuse across the cell membrane
  • Once in the epithelial cell, they are modified back into triglycerides inside the ER and Golgi body
17
Q

How is the formation of micelles important (refer to the structure too)

A

They enable the lipid digestion products to be transported to the small intestinal surface for absorption

18
Q

What are micelles

A

Water soluble vesicles formed of the fatty acids, glycerol, monoglycerides and bile salts

19
Q

What are the two stages involved in the digestion of lipids

A

Physical digestion: emulsification & micelle formation

Chemical digestion: hydrolysis of ester bonds in lipids

20
Q

What three digestive enzymes break down proteins

A
  • Endopeptidase
  • Exopeptidase
  • Membrane-bound dipeptidases
21
Q

How do membrane-bound dipeptidases work (what bonds do they catalyse the hydrolysis of) (what does it produce)

A

They catalyse the hydrolysis of peptide bonds between dipeptides (two amino acids)

22
Q

How do endopeptidases work (what bonds do they catalyse the hydrolysis of) (what does it produce)

A

They catalyse the hydrolysis of peptide bonds between the amino acids in the middle of a polypeptide chain

23
Q

How do exopeptidases work (what bonds do they catalyse the hydrolysis of) (what does it produce)

A

They catalyse the hydrolysis of peptide bonds between the amino acids at the end of a polypeptide chain

24
Q

State the path of protein digestion

A

It starts in the stomach and ends in the ileum (in the small intestines)

25
Where are the products of digestion absorbed across
The ileum epithelium into the bloodstream
26
How is glucose and galactose absorbed into the ileum epithelium then into the bloodstream
Active transport with sodium ions via co-transporter proteins
27
How is fructose absorbed into ileum epithelium then into the bloodstream
They are absorbed by facilitated diffusion through another transporter protein than glucose + galactose
28
How are monoglycerides and fatty acids absorbed into the ileum epithelium then into the bloodstream
* Micelles help move these products towards the epithelium where they release the products allowing the products to be absorbed * Monoglycerides and fatty acids are lipid-soluble, so can diffuse differently across the epithelial membrane
29
How are amino acids absorbed into the ileum epithelium then into the bloodstream
Active transport with sodium ions via co-transporter proteins
30
Describe the process of how amino acids and some monosaccharides (glucose and galactose) are absorbed
* Sodium ions are transported out of the epithelial cells in the ileum unto the blood using ATP - creating a concentration gradient as Na+ ion concentration decreases in the cell * Na+ ions then diffuse from the lumen of the ileum into the epithelial cell down the concentration gradient alongside the products of digestion through co-transporter protein * The products of digestion then moves out of the cell through down its concentration gradient facilitated diffusion through a channel protein