More lipids Flashcards

1
Q

What are lipids

A

biomolecules that are insoluble in water but are soluble in nonpolar organic solvents

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2
Q

Classes of Lipids

A

Saponifiable lipids and Non-saponifiable lipids

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3
Q

What is saponification

A

a reaction in which an ester is hydrolyzed using a strong base (like NaOH)
results in cleavage of the fatty acid from the glycerol backbone and produces a sodium salt fatty acid and glycerol

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4
Q

What does saponification create

A

a sodium salt fatty acid and a glycerol

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5
Q

What are the two sub-groups of saponifiable lipids

A

polar and nonpolar lipids

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6
Q

What are the two sub-classes of saponifiable- polar-lipids

A

phospholipids, and glycolipids

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7
Q

What is amphipathic

A

have both a hydrophilic and hydrophobic regions

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8
Q

What are saponifiable non-polar lipids

A

Triaclylglycerides

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9
Q

What is the major function of triacylglycerides

A

Storage lipids

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10
Q

What are two types of non-saponifiable lipids

A

Steroids and fat soluble vitamins

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11
Q

Non-Saponifiable lipids do not contain ____ bonds

A

ester

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12
Q

What are 2 fat soluble vitamins

A

A and E

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13
Q

What is the hydrophilic and reactive group of a fatty acid

A

the carboxylic acid

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14
Q

What dictates the function of a fatty acid

A

its structure

- more specifically its length and degree of saturation

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15
Q

What are some functions of lipids

A

Structural building blocks
Signal molecules
Energy storage

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16
Q

What are the 4 types of lipids

A

Enzyme Cofactors, Light absorbing pigments, Intracellular messengers, Hormones

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17
Q

What is the most significant property of lipids

A

Hydrophobic properties

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18
Q

The carboxylic acid group of a fatty acid forms what kind of bond with a glycerol backbone

A

ester

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19
Q

_____ fatty acids are released from adipocytes and occur from the breakdown of triglycerides

A

free

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20
Q

What do do free fatty acids bind to

A

plasma’s albumin protein and circulate in the blood

21
Q

Fatty acids are consumed by _____ to make ATP thru ________

A

mitochondria, Beta-Oxidation

22
Q

the notation 18:0 denotes what

A

18 carbons and 0 double bonds

23
Q

fatty acid chains are not what in animals but are in archaea

24
Q

why are saturated fatty acids more stable

A

greater van der Waals forces with neighboring tails; tough to separate
tails pack tightly together so can stack and become solid more easily

25
Saturated fatty acids are ____ at room temp
Solids
26
Saturated fatty acids have a _______ membrane fluidity when compared to unsaturated
decreased
27
Do proteins have difficulty crossing saturated fats
yes
28
The conformation of unsaturated fatty acids in biological terms is always
Cis
29
What happens to solubility when the chain of a fatty acid grows
it becomes more insoluble
30
What is the maximum length of a fatty acid that our body can make
18 carbons
31
How long are short chain fatty acids
less than 6 carbons
32
where do short chain fatty acids get absorbed
directly into the bloodstream via the portal vein
33
How long are medium Chain fatty acids
6-12 carbons
34
Where are medium fatty acids absorbed
directly into the bloodstream via the portal vein
35
How long are long chain Fatty acids
13-21 Carbons
36
Where do long chain fatty acids get absorbed
in the walls of the small intestine and reassembled into triglycerides, coated with cholesterol and a protein forming chylomicrons - The chylomicrons are released into the lymphatic system into the thoracic duct and travel up to the subclavian vein where it is released in the bloodstream to be stored in tissues
37
what is the only end of a fatty acid that is ionizable
carboxyl end
38
Humans do not have the ability to insert double bonds beyond carbon #_____
10 inbetween 9-10 is our last one
39
what is the function of omega 9 fatty acids
help to lower bad cholesterol, increase good cholesterol and control blood sugar
40
Where are omega 6 fatty acids found
in vegetable oil
41
what is the function of omega 6 fatty acids
helps with the regulation of blood flow and blood cholesterol
42
What is the common name for omega 6 FA
linoleate (18:2) and Arachidonate (20:4)
43
What is the common name for omega 3 FA
Linolenate
44
Which of the omega FA do we want the highest percentage of
omega 3 FA
45
Where are omega 3 FA found
found in fish oil and originate from phytoplankton
46
What is the function of omega 3 FA
has an anti-inflammatory effect which is beneficial to the heart to prevent atherosclerosis
47
Sphingophospholipids have an _____ alcohol that contains _______ long hydrocarbon chain connected via the primary hydroxyl group to a ________ via a __________ bond
amino, unsaturated, phosphorylcholine, phosphodiester bond
48
Sphingophospholipids play an important role in
cell recognition and binding