Morphine Sulfate

Question 1

MORPHINE SULFATE

Pharmacology & Actions

Answer 1

• Narcotic analgesic
• Alleviates pain by acting on the pain receptors in the brain, elevates pain threshold
• CNS depression, depresses brainstem respiratory centers
• Increases venous pooling, vasodilators arterioles, reducing preload and afterload
• Histamine release

Question 2

MORPHINE SULFATE

Indications

Answer 2

• Analgesia

Question 3

MORPHINE SULFATE

Absolute Contraindications

Answer 3

• Respiratory and/or CNS depressant
• Hypotension
• Morphine sulfate allergy

Question 4

MORPHINE SULFATE

Precautions & Side Effects

Answer 4

• Morphine causes neurological and respiratory depression. Respiratory depression may be worse in patients with underlying lung disease or concomitant use of other depressant drugs such as benzodiazepines or alcohol
• Morphine can be reversed with naloxone (narcan)
• Check and document vital signs and patient response after each dose
• When morphine is given to treat pain, the goal is reduction of pain not total elimination of pain

Question 5

MORPHINE SULFATE

Administration

Answer 5

• IV
• Onset: Seconds
• Peak Effect: 20min
• Duration: 2-4hrs