Motivation Flashcards

1
Q

Inhibitory signals

A

leptin, insulin, and PYY

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2
Q

Stimulatory signals

A

ghrelin from the stomach

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3
Q

hypothalamus-pituary complex

A

command center of the endocrine system

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4
Q

paraventricular zone of the hypothalamus

A

controls the ANS

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5
Q

Arcuate nucleus

A

center of energy regulation in hypothalamus`

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6
Q

Satiety neurons

A

POMC/CART

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6
Q

Hunger neurons

A

AgRP/NPY

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7
Q

Anoretic peptides

A

αMSH and CART

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8
Q

Orexigenic peptides

A

AgRP/NPY

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9
Q

Elevated leptin

A
  1. POMC/CART neurons release anoretic peptides
  2. Activate PVN neurons that release TSH and ACTH from anterior pituary to raise metabolic rate
  3. Inhibit lateral hypothalamus neurons to inhibit feeding behavior
  4. Activate sympathetic division of ANS
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10
Q

Decreased leptin

A
  1. AgRP/NPY neurons release orexigenic peptides
  2. Inhibit PVN neurons that release TSH and ACTH from anterior pituary to decrease metabolic rate
  3. Activate lateral hypothalamus neurons to stimulate feeding behavior
  4. Activate parasympathetic division of ANS
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11
Q

The timing of reward

A
  1. Learn to recognize a reward cue: associating
  2. Mobilize and go after the reward: wanting
  3. Savor the reward: liking
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12
Q

Anatomy of reward system

A

ventral tegmental area, nucleus accumbens,and PFC

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13
Q

What neurotransmitter does the VTA release?

A

dopamine

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14
Q

Two pathways

A

mesolimbic and mesocortical

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15
Q

Mesolimbic pathway

A

VTA to NA

16
Q

Mesocortical

A

VTA to PFC

17
Q

VTA

A

Learning association between cues and potential reward

18
Q

NAc

A

Important for mobilizing effort for reward

19
Q

Largest recipient of dopamine in the brain

A

NAc

20
Q

Involved in decision-making and cost-benefit analysis

A

PFC

21
Q

Effect of drugs on the reward system

A

Prolong dopamine activation or potentiate neuronal activation in NAc and VTA

22
Q

Net effect of addiction

A

Chronic decrease in basal activity and increase in phasic activity in presence of abusive drug

23
Q

PFC addicted brain

A

decreased activity

24
Q
A