MS Flashcards

1
Q

What are 3 main phases in menstrual cycle?
What days occur?

A

Follicular phase = days 1-13/14
Ovulation = days 13/14
Luteal phase = days 14-28

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2
Q

What occurs during luteal phase?

A

Follicle collapses
Granulosa cells increase size
Becomes corpus luteum

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3
Q

What do granulosa cells secrete?

A

Oestrogen
Progesterone
Inhibin

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4
Q

What does the granulosa become during luteal phase?

A

Corpus luteum

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5
Q

What occurs to the corpus luteum if the egg is not fertilised?

A

Undergo apoptosis

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6
Q

What triggers apoptosis?

A

Menstruation

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7
Q

What is the corpus luteum called if it collapses?

A

Corpus albicans

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8
Q

What marks end luteal phase?

A

Collapse of corpus luteum into corpus albicans

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9
Q

What are main uterine phases? (3)

A

Day 1-5 Menstrual Phase
Day 5-14 Proliferative Phase
Day 15-28 Secretory phase

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10
Q

What days does the: occur
Menstrual
Proliferative
Secretory

A

Day 1-5 Menstrual Phase
Day 5-14 Proliferative Phase
Day 15-28 Secretory phase

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11
Q

What hormone change leads to endometrial degeneration?

A

Withdrawal progesterone

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12
Q

What occurs day 1-5 (menstrual phase)?

A

Withdrawal progesterone lead endometrial degeneration

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13
Q

What occurs day 5-14 (proliferative phase)?

A

Oestrogen from granulosa cells and theca cells cause endometrium thicken
Stimulate myometrium
Stimulate progesterone receptor generation in endometrium

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14
Q

What do granulosa and theca cells secrete during proliferative phase?
Effect?

A

Oestrogen
Endometrium thickens

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15
Q

What stimulates thickening of endometrium?

A

Oestrogen secretion from granulosa and theca cells

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16
Q

What are 3 layers of uterus?

A

Endometrium- inner
Myometrium- middle
Perimetrium- outer

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17
Q

Label

A
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18
Q

What does oestrogen stimulate in proliferative phase? (3)

A

1) Endometrium thickens
2) Stimulates myometrium (middle)
3) Stimulate progesterone receptor generation in the endometrium

19
Q

What are 4 phases of menstruation cycle?

A

Menstrual phase
Follicular phase
Ovulation phase
Luteal phase

20
Q

When does menstrual phase occur?

A

Egg isn’t fertilised

21
Q

What hormones fall in menstrual stage?

A

Oestrogen and progesterone

22
Q

What hormone changes occur in follicular phase?

A

FSH increases

23
Q

Function of FSH in follicular phase?

A

Stimulate ovaries produce follicles

24
Q

What stimulates release FSH?

A

Hypothalamus signals pituitary gland to release FSH

25
When is lining of uterus thickened?
Follicular phase
26
What do rising oestrogen lvls in follicular phase trigger?
Pituitary gland to release LH
27
What does the follicle turn into if the egg is released?
Corpus luteum
28
What hormones does the corpus luteum release?
Progesterone and oestrogen
29
Function of progesterone and oestrogen?
Uterine lining kept thick- ready fertilised egg to implant
30
What hormone is produced if pregnant?
Production hCG
31
Function of hCG?
Maintain corpus luteum Keep uterine lining thick
32
What is avg length of luteal phase?
14 days
33
What are the 4 phases of menstrual cycle? Outline cycle
1) Menstruation- shed thicken lining 2) Follicular phase- start ovulate, 1 egg matures 3) Ovulation- mature egg down falopian tube 4) Luteal phase- follicle produces hormones- thicken ripen uterus
34
35
What stimulates secretion of FSH and LH by pituitary?
GnRH from hypothalamus
36
What does GnRH stimulate? From where?
GnRH from hypothalamus stimulates secretion of FSH and LH by pituitary
37
What does LH surge cause?
Ovulation- day 14
38
What causes ovulation?
Surge in LH
39
What does corpus luteum secrete?
Progesterone and estrogens
40
41
Is follicular or luteal phase first?
Follicular then luteal
42
How does high oestrogen effect mucus secretion? Function?
High oestrogen- clear, abundant, watery secretion Sperm movement and implantation
43
What is effect of progesterone and oestrogen on mucus? Function?
Progesterone and oestrogen- thick and sticky Stop bacteria entering Offer protection to implanted egg