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Reproduction > Sex determination > Flashcards

Sex determination Flashcards

1
Q

When is sex determined?

A

At fertilisation

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2
Q

What gene determines sex?

A

Lack of or presence of SRY gene on Y chromosome

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3
Q

If Y chromosome contains SRY gene what does lead to?

A

Development testis

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4
Q

If no sex determining region of SRY what does lead to?

A

Ovary development

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5
Q

What does non-functional X in female gonads condense to form?

A

Barr body

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6
Q

If +SRY
If -SRY

A

+SRY lead to development testes
-SRY development ovary

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7
Q

What forms genital organs?

A

Intermediate mesoderm
Genital ridge

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8
Q

What two ducts are present?

A

Wolffian ducts
Mullerian ducts

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9
Q

Where do germ cells for sperm and ova come from?

A

Yolk sac of hindgut

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10
Q

What duct system present in males?

A

Wolffian duct (mullerian regresses)

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11
Q

What cells responsible for regression of mullerian duct in males?

A

Sertoli cells- produce mullerian inhibitory factor (MIF)
Leads to testis determining factor
Influence formation male gonads

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12
Q

What does the SRY gene induce?

A

MIF- regress mullerian

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13
Q

Outline how male duct formed?

A

1) SRY induces MIF
2) Sertoli cells produce MIF
3) MIF leads to testis determining factor
4) Mullerian regresses
Wolffian duct remains

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14
Q

What produces testosterone?

A

Leydig cells

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15
Q

What is the wolffian duct converted into? (4)

A

Epididymis
Vas deferens
Ejaculatory duct
Seminal vesicles

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16
Q

What effect does testosterone have on testes?

A

Cause testes descend into scrotum

17
Q

Function of DHT (from testosterone)?

A

Development penis, scrotum, prostate

18
Q

What do sertoli cells produce?

A

Mullerian Inhibitory factor

19
Q

Males
Females
What duct is present?

A

Males- wolffian
Female- mullerian

20
Q

How is mullerian duct formed in females?

A

1) No SRY gene
2) No MIF produced meaning mullerian system develops
3) Mullerian duct produces- fallopian tube, uterus, upper 2/3 vag

21
Q

Where does the lower 1/3 vagina and external genitalia develop from?

A

Urogenitial sinus

22
Q

Name 3 things the mullerian duct produces?

A

Fallopian tubes
Uterus
Upper 2/3 vagina

23
Q

Name 2 things urogenital sinus produces?

A

Lower 1/3 vagina
Ecxternal genitalia

24
Q

Presence of SRY gene means?

A

Male- MIF produced

25
Q

Name 3 things oestrogen forms?

A

Uterus
Cervix
Vagina
Clit

25
Q

Name 3 things oestrogen forms?

A

Uterus
Cervix
Vagina
Clit

Reproduction (11 decks)

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