MSCT Week 5: Acne and Diseases of the Follicle

Question 1

Follicle Definition

Answer 1

the structure that produces the hair shaft

Question 2

Basic types of hair shafts

Answer 2

• Vellus hairs
• Terminal hairs

Question 3

Question 1

Answer 3

~100,000 hair follicles on the scalp

Question 4

Question 2

Answer 4

~100 hairs

Question 5

Facts about hair

Answer 5

Question 6

Areas of skin without hairs

Answer 6

• Glaborous skin
• palms and volar surfaces of fingers
• soles of feet
• mucosal surfaces

Question 7

Facts about hair loss

Answer 7

Question 8

hair follicles are immunologically privledged sites

Answer 8

Question 9

Hair follicle cycle of growth

Answer 9

Question 10

Hair follicle cycle

Anagen & Catagen phases

Answer 10

Question 11

Hair follicle cycle

Telogen & Exogen phases

Answer 11

Question 12

Anagen phase

Answer 12

• the production phase of the follicle
• Estrogens prolong
• Androgens increase growth rate in more dependent follicles
• 85-90% of scalp follicles are in this phase at any one time

Question 13

Catagen Phase

Answer 13

• Regression of follicle
• less than 1% of scalp follicles at any one time
• a hair follicle in this phase can spend 2-3 weeks regressing

Question 14

Telogen Phase

Answer 14

Resting phase of follicle

10-15% of scalp follicles at any one time are in this phase

A follicle resting in this phase can retain a hair shaft for up to 3 months

Question 15

Exogen Phase

Answer 15

• Shedding of the hair shaft
• actually occurs in early part of anagen phase as the follicle starts to regenerate and grow a new hair shaft
• Involves not only a mechanical displacement of old hair shaft by new hair shaft but a proteolytic process freeing the shaft from the follicle
• 100-150 hairs shed per day

Question 16

Question 3

Answer 16

Around 20 cycles per lifetime

Question 17

Question 4

Answer 17

80-85%

Question 18

Acne epidemiology/associations/long-term effects

Answer 18

Question 19

Acne Who is more likely to get acne?

Answer 19

Question 20

Question 5

Answer 20

Blockage of the pilosebaceous unit with keratin debris

Question 21

Acne Pathogenesis

4 steps

Answer 21

Question 22

Acne Causative agent

Answer 22

Propionibacterium acnes

Question 23

Question 6

Answer 23

All of the above

Question 24

Acne Triggers

6 listed

Answer 24

Question 25

Acne Severity

Answer 25

Question 26

Acne types

Answer 26

Question 27

Acne Conglobata & Fulminans Descriptions

Answer 27

Question 28

Acne Conglobata & Fulminans Treatment

Answer 28

Corticosteroids & Isotretinoin

Question 29

Acne Fulminans description

Answer 29

Conglobata so severe that it elicits a systemic inflammatory response Isotretinoin & Corticosteroids

Question 30

Categorizing Acne for Treatment

Answer 30

Question 31

Associated Inflammatory Symptoms of Acne

Answer 31

PAPA(SH): Pyogenic arthritis, pyoderma, gangrenosum, (cystic) Acne & Hidradenitis Suppuritiva

Question 32

Comedonal Acne Treatment

Answer 32

* Topical Retinoid (BEST) * Salicylic Acid

Question 33

Mild Inflammatory or Mixed Acne Treatment

Answer 33

Combo topical therapy * BP * Antibiotic * Retinoid

Question 34

Moderate inflammatory or Mixed Treatment

Answer 34

Combo Topical Therapy BP Antibiotic Retinoid + Oral antibiotic

Question 35

Severe inflammatory or Mixed Treatment 4 listed

Answer 35

Combo Topical Therapy Benzoyl Peroxide Antibiotic Retinoid + Consider hormonal or isotretinoin

Question 36

Hormonal Acne Treatment 3 listed

Answer 36

OCP (oral Contraceptive Pills) Spironolactone (BP med but blocks androgens) +/- Topicals

Question 37

Nodulocystic Acne Treatment 1 listed

Answer 37

Isotretinoin

Question 38

Isotretinoin is a

Answer 38

Oral retinoid

Question 39

Question 7

Answer 39

Topical Retinoid Tretinoin

Question 40

Question 8

Answer 40

Topical Antibiotics and or oral antibiotics

Question 41

Treating Acne in Adolescence

Answer 41

Question 42

Postinflammatory Dyspigmentation

Answer 42

Question 43

Acne Scarring

Answer 43

Question 44

Question 9

Answer 44

Neonatal cephalic pustulosis (malessezia) Acne mimic Reassure No treatment required

Question 45

Infantile and Childhood Acne Presents as? Cause? Scar? Treat how?

Answer 45

Question 46

Childhood Acne Diagnosis? Precocious puberty? How to test?

Answer 46

Question 47

Hidradenitis Suppuritiva

Answer 47

Question 48

Question 10

Answer 48

* Folliculitis * Hot Tub Folliculitis (Pseudomonas) * Recent Hot Tub Exposure

Question 49

Folliculitis

Answer 49

Question 50

Other Folliculitis Examples

Answer 50

Question 51

Question 11

Answer 51

80-90%

Question 52

Subtypes of Alopecia 7 listed

Answer 52

Question 53

Question 12

Answer 53

alopecia areata and Hypothyroidism is related

Question 54

Lichen Planus Pilaris Pathology

Answer 54

Scar and destroy hair follicles

Question 55

Alopecia Areata is related to...

Answer 55

Hypothyroidism

Question 56

Alopecia Areata

Answer 56

Question 57

Alopecia Areata Increases risk for

Answer 57

* autoimmune thyroid problems * vitiligo * Pernicious Anemia (immune system kills B12 absorbing cells) was fatal before injections

Question 58

Alopecia Areata Scar formation

Answer 58

Non-scarring

Question 59

Androgenic Alopecia in men and women

Answer 59

Question 60

Trichotillomania

Answer 60

Question 61

Question 13

Answer 61

Anagen

Question 62

anagen vs telogen effluvium

Answer 62