Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

MSCT > MSCT Week 6: Neoplasms of the Skin > Flashcards

MSCT Week 6: Neoplasms of the Skin Flashcards

(73 cards)

Start Studying
1
Q

Question 1

A

This is a common benign proliferation of keratinocytes Seborrheic keratosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Seborrheic keratosis Clinical Description

5 listed

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Sign of Leser-Trelat

Step 1

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Identify

A

Seborrheic Keratosis

  • well demarcated
  • mushroom epidermis
  • horn cysts(spaces in the tumor filled with keratin)
  • benign
  • regular looking cells
  • wouldn’t see a lot of mitosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

A benign proliferation of keratinocytes

A

Seborrheic keratosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is this?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Mitoses and atypia in seborrheic keratosis

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is this depicting?

A

Mitoses and atypia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Question 2

A

C is correct

A is Basal cell Carcinoma

B is a Melanoma

C is a benign Nemus

D Seborrheic Keratosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Nevus definition

What does nevus mean?

What is a Nevi?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Nevus clinical characteristics

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Benign Pigmented Lesions AKA

A

Nevus or Naevi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Identify

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Identify

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Identify

A

symmetrical

melanocytes get smaller with depth

would not expect to see atypia or mitoses

in a benign nevus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Benign Nevus Histology Characteristics

6 listed

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q
A

Benign Naevia melanocytes get smaller as you go down

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Question 3

Which of the following lesions is of most concer?

A

Correct Answer: A

A Melanoma

B Seborrheic Keratosis

C & D Benign Melanocytic Lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

ABCDE of Melanoma

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Subtypes of Melanoma

4 listed

A
  • Superficial Spreading Melanoma
  • Nodular Melanoma
  • Acral Lentiginous Melanoma
  • Lentig maligna Melanoma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Lentigo Maligna Melanoma

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Acral Lentigous Melanoma

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Nodular Melanoma

A

more deadly spreads vertically

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Superficial Spreading Melanoma

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
* Melanoma * nests of melanocytes (should be in basal layer but are extending up through the epidermis) * Atypical big melanocytes * Mitoses * Pagetoid spread of melanocytes (upward spread of melanocytes * melanocytes dont get smaller deeper in the dermis
26
Melanoma
27
Mitoses in melanoma
28
Histologic Features of Melanoma vs Naevi
29
Question 4
* Depth of invasion * Tumor thickness is the most important feature of melanoma * 10 year survival decreases with melanoma depth
30
Mutation common in Melanoma
BRAF V600E
31
Pharmacotherapy of Melanoma
32
Describe all lesions
A Crusted Plaque B multicolored hyperpigmented shiny plaque C shiny Vesicle with telangiectasia D cryterraform hyperkeratotic nodule
33
Question 5
**Correct Answer: C** A Squamous cell carcinoma B Melanoma C Basal Cell Carcinoma D Squamous cell carcinoma
34
Clinical Features of Basal Cell Carcinoma 6 listed
35
Question 6
Correct answer: A A Basal Cell Carcinoma B Squamous cell Carcinoma C Melanoma
36
Basal Cell Carcinoma Histological Features 5 listed
* basaloid (blue) * basaloid tumor islands * artifactual clefting around the nests * nests themselves have peripheral palisading nuclei * mucin blue stringy material
37
Basal Cell Carcinoma
38
Basal Cell carcinoma Clinical Features 4 listed
39
Basal Cell Carcinoma PAthogenesis
Sun exposure Genetic factors may also play a role
40
What is this?
Actinic Keratosis
41
42
Histological Features of Actinic Keratosis 5 listed
43
Question 8
**Correct Answer: D** a premalignant lesion caused by sun exposure and if left untreated about 10% would transform into squamous cell carcinoma
44
Actinic Keratosis Clinical Features
45
Describe lesions? Which is Malignant?
Pink or red plaque some red scale next lesion red plaque with white crusted scale
46
epidermis does not look normal diffusely enlarged keratinocytes full thickness atypia of the epidermis and mitoses
47
squamous cell carcinoma
48
Squamous Cell Carcinoma Histological Features
49
Squamous Cell Carcinoma Clinical Features 5 listed
50
Identify
squamous cell carcinoma is very pink because it is keratinizing Keratin pearls
51
Histological Features of Invasive Squamous Cell Carcinoma
52
Invasice Squamous Cell Carcinoma Clinical Characteristics
53
Invasive Squamous Cell Carcinoma details 4 listed
54
Pathogenesis of Invasive Squamous Cell Carcinoma
55
Etiology of Skin Cancer
UV Radiation UVA tanning and photoaging UVB causes sunburn UVC filtered out by atmosphere
56
How does UV Radiation damage DNA
57
Xeroderma Pigmentosum
58
Pyogenic Granuloma AKA
Lobular Capillary Hemangioma
59
Pyogenic Granuloma Clinical Features
60
Infantile Hemangiomas Clinical Features
61
Hemangiomas Additional details
62
Cherry Angioma Clinical Features
63
Glomus Tumor Clinical Features 4 listed
64
Identify
Kaposi Sarcoma related to HHV8 Viral Infection purplish plaques in immunosuppressed patients purple plaques or nodules treatment reverse immunosuppression
65
Histological Features of Kaposi Sarcoma
66
Herpes Virus 8
Kaposi Sarcoma
67
Angio Sarcoma Clinical Features 4 listed
68
Seborrheic Keratosis Summary
leser trelot sign be concerned
69
Nevus Sumary
70
Melanoma Summary
71
Basal Cell Carcinoma Summary
72
Actinic Keratosis to Squamous Cell Carcinoma Summary
73
summary of Vascular Lesions
pyogenic granuloma hemangioma cherry angioma Kaposi Sarcoma malignant vascular neoplasm herpes virus 8 reverse immunosuppresion Glomus Tumor smooth muscle capillary cells pain in exposure to cold

MSCT (30 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions