MSK

Question 1

Pectus carinatum / excavatum can be associated with …

Answer 1

Rickets

CTD e.g. Marfan/Ehler-Danlos, Noonan

Question 2

TB arthritis most commonly affects which joints

Answer 2

WB joints - HIP, knee

Question 3

Juvenile idiopathic arthritis (JIA) definition

Answer 3

Joint inflamm (pain, stiffness, swelling, reduced movement) in:
<16yo
>6w

Question 4

Most common type of JIA and how many joints affected

Answer 4

Oligoarticular JIA
4 OR LESS joints in first 6m of illness

NB higher risk of uveitis in oligoarticular JIA

Question 5

Which complication is more common in ANA-positive JIA?

Answer 5

Anterior uveitis -> slit-lamp examinations needed every 3-6m after dx

NB higher risk of uveitis in oligoarticular JIA

Question 6

Polyarticular JIA definition and can be further divided into which 2 categories?

Answer 6

Joint inflamm in 5 OR MORE joints in first 6m of illness

a) RF +ve (more likely to develop into RA later) - affects more girls

and

b) RF -ve

Often SYMMETRICAL involvement of both small/large joints

Question 7

Which genetic marker is a risk factor for JIA?

Answer 7

HLA-B27
- especially in enthesitis-related arthritis (inflammation where tendons + ligaments attach to bone, affects boys more)

Question 8

Which joints are most commonly affected in oligoarticular JIA?

Answer 8

Knee, ankle (lower extremities)
Also: wrist, elbows

Question 9

Which joints are most commonly affected in polyarticular JIA?

Answer 9

Symmetrical joints affected

RF +ve
Most commonly small joints of hands/wrists
(can also affect large)

RF-ve
Any joint
TMJ commmon

Question 10

Enthesitis-related arthritis commonly affects…

Answer 10

Lower back
LL

Question 11

Systemic JIA fevers for at least …
What other signs/sx?

Answer 11

2 weeks
Rash - salmon pink
Usually several, symmetrical joints affected
Hepatosplenomegaly
Serositis: pericarditis, peritonitis, pleuritis