Neuro

Question 1

Mx of infantile spasms (West syndrome)

Answer 1

Vigabatrin (also given in tuberous sclerosis)
ACTH (?thought to incr steroid release) / prednisolone

Question 2

EEG finding in infantile spasms (West syndrome)

Answer 2

Hypsarrhythmia

Question 3

EEG finding in Lennox-Gastaut syndrome

Answer 3

Slow spike and wave activity

Question 4

Features of Lennox Gastaut syndrome

Answer 4

Multiple diff seizure types in one
Rare, severe, frequent and difficult to control seizures
Cognitive impairment / DD
Mostly structural brain malformation e.g. from abnormal development, genetic anomalies, infections in preg, injuries

Question 5

First line treatment in GTCS, myoclonic, tonic, atonic seizures

Answer 5

Sodium valproate

Question 6

First line treatment in absence (typical or atypical seizures)

Answer 6

Ethosuximide