MSK Flashcards

(7 cards)

1
Q

Radiographic findings of osteosarcoma

A

Destruction of normal trabecular bone pattern

Mixed radiodense (sclerotic) and radiolucent (lytic) areas

Periosteal new bone formation with lifting of the periosteum → forming a Codman triangle

“Sunburst” pattern of ossification in adjacent soft tissue

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2
Q

What is Paget disease of the bone?

A
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3
Q

What are common manifestations of Paget disease of the bone?

A
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4
Q

What are the three most common complications of Paget disease of the bone?

A
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5
Q

What are the signs and symptoms of an acute gout attack?

A

An acute gout attack typically presents with sudden, intense joint pain, most often affecting the big toe (a condition known as podagra), though other joints such as the ankles, knees, elbows, wrists, and fingers can also be involved. The affected joint becomes swollen, red, warm, and extremely tender, often to the point where even the weight of a bedsheet is intolerable.

These attacks frequently occur at night and reach peak intensity within 12 to 24 hours. Following the acute phase, discomfort may persist for several days to weeks, and subsequent attacks may last longer and affect multiple joints.

Neutrophilic effusion

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6
Q

What does negative versus positive birefringence indicate in crystal-induced arthritis?

A

Birefringence refers to the optical property of crystals that causes them to refract light in two different directions under polarized light microscopy.

In the context of crystal-induced arthritis, monosodium urate crystals, which are responsible for gout, exhibit negative birefringence. These needle-shaped crystals appear yellow when aligned parallel to the axis of the red compensator and blue when perpendicular.

Conversely, calcium pyrophosphate dihydrate crystals, associated with pseudogout, show positive birefringence. These rhomboid-shaped crystals appear blue when parallel and yellow when perpendicular to the red compensator axis. Identifying the type of birefringence is crucial for distinguishing between gout and pseudogout

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7
Q

Commonly injured neurovascular structure in posterior knee dislocation?

A

Popliteal artery:

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