MSK Pathology Flashcards
(123 cards)
Degenerative joint disease (DJD) Degenerative osteoarthritis (OA)
Degeneration of articular cartilage with hypertrophy of subchondral bone and joint capsule of weight-bearing joints
Meds: corticosteroids, NSAIDs, glucocorticoid injections, acetaminophen (mild pain)
Diagnostic tests: plain film (diminished joint space, decreased height of articular cartilage, osteophytes) and lab tests (rule out RA)
PT GOALS:
joint protection strategies
Ankylosing spondylitis
Marie-Strumpell disease, Bechterew’s disease, rheumatoid spondylitis
Progressive inflammatory disorder that initially affects the axial skeleton
Initial onset before 4th decade; men 3x more
First sx = mild and low back pain, morning stiffness and sacroilitis (3+ months duration)
Leads to kyphotic deformity of CS/TS and decreased lumbar lordosis
Degeneration of peripheral and costovertebral joints in advanced stages
Meds: NSAIDs, corticosteroids, cytotoxic drugs, tumor necrosis factor inhibitors
Diagnostic tests: HLA-B27 antigen
PT GOALS:
flexibility exercises
relaxation activities–breathing strategies
Gout
Genetic disorder of purine metabolism –> elevated serum uric acid (hyperuricemia) which forms crystals that deposit in peripheral joints (knee/great toe) and other tissues (kidneys)
Meds: NSAIDs, COX-2 inhibitors, colchicine, corticosteroids, ACTH, allopurinol, probenecid and sulfinpyrazone
Diagnostic tests: lab tests identify monosodium rate crystals in synovial fluid and/or connective tissue samples
PT GOALS:
pt education for injury prevention
Psoriatic arthritis
Chronic, erosive inflammatory disorder (digits and axial skeleton) associated with psoriasis
Meds: acetaminophen, NSAIDs, corticosteroids, disease-modifying antirheumatic drugs (DMARDs), biological response modifiers (BRMs)–Enbrel
Diagnostic tests: lab tests rule out RA
PT GOALS:
joint protection strategies
Rheumatoid Arthritis (RA)
Chronic systemic disorder in a symmetrical pattern of dysfunction in synovial tissues and articular cartilage of hands, wrists, elbows, shoulders, knees, ankle and feet
Women 2x more than men
**MCP/PIP: panes formation (inflamm granulation tissue covering joint surface), ulnar drift, volar subluxation of MCP
**swan neck and boutonniere deformity, Bouchard’s nodes (excess bone formation on dorsal PIP)
JRA: onset
Osteoporosis
Metabolic disease that depletes bone mineral density/mass predisposing individual to fracture
Women 10x > men
Common fracture sites: TS/LS, femoral neck, proximal humerus/tibia, pelvis, distal radius
Primary = decreased estrogen production
Senile = decreased bone cell activity due to genetics or acquired abnormalities
Meds: calcium, vitamin D, estrogen, calcitonin, and biophosphonates
Diagnostic tests: CT, single and dual photon absorptiometry
PT GOALS:
joint/bone protection strategies
Osteomalacia
Decalcification of bones due to vitamin D deficiency
Sx: severe pain, fractures, weakness, deformities
Meds: calcium, vitamin D, vitamin D injections (calciferol–vitamin D2)
Diagnostic tests: plain film, lab tests, bone scan, bone biopsy
PT GOALS:
joint/bone protection strategies
Osteomyelitis
Inflammatory response within bone caused by infection (staphylococcus aureus)
Children and immunosuppressed adults (male)
Meds: antibiotics, proper nutrition, surgery if spreads to joints
Diagnostic tests: lab tests (infection), bone biopsy
PT GOALS:
joint/bone protection strategies and cast care
Arthrogryposis multiplex congenita
Congenital deformity of skeleton and soft tissues limiting joint motion and “sausage-like” appearance of limbs; normal intelligence
Diagnostic tests: plain films
PT GOALS:
joint/bone protection strategies
pt education regarding adaptive devices
flexibility exercises
Osteogenesis imperfecta
Inherited disorder (autosomal dominant) leading to abnormal collagen synthesis creating imbalance between bone deposition and reabsorption Cortical and cancellous bone become thin leading to fractures/deformity of WB bones
Meds: calcium, vitamin D, estrogen, calcitonin and biophosphonates
Diagnostic tests: bone scan and plain film, serological testing
PT GOALS:
joint/bone protection strategies
Osteochondritis dissecans
Separation of articular cartilage from underlying bone (osteochondral fracture) usually medial femoral condyle near intercondylar notch or humeral capitellum
Surgery indicated if displaced
Diagnostic test: pain film or CT scan
PT GOALS:
joint/bone protection strategies
flexibility exercises
Myofascial pain syndrome
“Trigger point”: focal point of irritability within a muscle; taut, palpable band within muscle
Active = tender, referral pattern of pain when provoked
Latent = palpable taut bands, not tender, can become active
Onset: sudden overload, overstitching and/or repetitive/sustained muscle activities
Medical intervention: dry needling, injection of analgesic, corticosteroid
PT GOALS:
flexibility exercises
manual therapy: soft tissue, jt mobs, “spray and stretch” technique, dry needling, modalities and manual pressure
strength, power and endurance exercises
Tendonosis/Tendonopathy
Common tendon dysfunction (supraspinatus, common extensor tendon of elbow, patella, Achille’s tendon)
Histological charac: hypercellularity, hypervascularity, no inflammatory infiltrates, poor organization/loosening of collagen fibrils
Meds: acetaminophen, NSAIDs, and/or steroid injection
Diagnostic tests: possibly MRI
PT GOALS: flexibility exercises manual therapy: soft tissue and joint mobs endurance and strengthening (ECCENTRIC) modalities pt education for IADLs
Bursitis
Inflammation of bursa due to overuse, trauma, gout or infection
S/S: pain with rest, limited motion due to pain (non-capsular pattern)
Meds: acetaminophen, NSAIDs, and/or steroid injection
PT GOALS: flexibility exercises manual therapy: soft tissue and joint mobs modalities pt education for IADLs
Muscle strains
Inflammatory response within muscle due to micro tearing of musculotendinous fibers
Pain and tenderness within muscle
Meds: acetaminophen and/or NSAIDs
Diagnostic tests: MRI if necessary
PT GOALS: flexibility exercises manual therapy: soft tissue and joint mobs modalities pt education for IADLs
Myositis ossificans
Painful condition of abnormal calcification within muscle belly (quadriceps, brachial and biceps brachii) due to direct trauma leading to a hematoma and calcification
**Can be induced by early mobilization and stretching
Meds: acetaminophen and/or NSAIDs
Surgery: if nonhereditary and after maturation of the lesion (6-24 months) when lesions interfere with joint movement or impinge on nerves
Diagnostic tests: plain films, CT scan or MRI
PT GOALS:
flexibility exercises
manual therapy: soft tissue and joint mobs
NOTE: avoid aggressive soft tissue/massage techniques which may worsen condition
Complex regional pain syndrome (CRPS)
Dysfunction of SNS: pain, circulation and vasomotor disturbances
CRPS I: frequently triggered by tissue injury; its with above sx but no underlying nerve injury
CRPS II: same sx but clearly associated with a nerve injury
Medical intervention: sympathetic nerve block, surgical sympathectomy, spinal cord stimulation, intrathecal drug pumps
Meds: topical analgesics, anti seizure drugs, antidepressants, corticosteroids and opioids
Long term changes: muscle wasting, trophic skin changes, decreased bone density, decreased proprioception, loss of muscle strength from disuse and joint contractors
PT GOALS: pt education for injury prevention/reduction desensitization activiies flexibility exercises TENS for pain relief
Paget’s disease
osteitis deformans
Metabolic bone disease involving abnormal osteoclastic and osteoblastic activity leading to spinal stenosis, facet arthropathy and possible spinal fracture
Unknown etiology: possibly viral infection and/or environmental
Meds: acetaminophen, calcitonin and etidronate disodium (limit osteoclastic activity)
Diagnostic test: plain film, lab tests (increased serum alkaline phosphatase and urinary hydroxyporline)
PT GOALS:
joint/bone protection strategies
Idiopathic scoliosis
Structural: irreversible lateral curvature of spine with a rotational component
Nonstructural: reversible lateral curvature of spine without rotational component and straightening as individual flexes spine
Intervention (structural): bracing and possible surgery (Harrington rods placement)
45 deg: surgery
Diagnostic test: plain film (full-length Cobb’s method), CT scan and/or MRI to rule out associated conditions
PT GOALS:
flexibility exercises
application/pt education with orthoses
Torticollis
Spasm and/or tightness of sternocleidomastoid
SB toward and rotation away from affected SCM
Meds: acetaminophen, muscle relaxants and/or NSAIDs
PT GOALS:
flexibility exercises
manual therapy: soft tissue, joint mobs
Glenohumeral Subluxation and Dislocation
95% in anterior-inferior direction: when abducted UE is forcefully ER causing tearing of the inferior GH ligament, anterior capsule and occasionally glenoid labrum
Posterior dislocation: horizontal add and IR
Complications:
Hill-Sachs lesion: compression fracture of posterior humeral head
SLAP lesion: tearing of superior glenoid labrum from anterior to posterior
Bankart’s lesion: avulsion of anteroinferior capsule and ligaments associated with glenoid rim
Bruising of axillary nerve
Following surgical repair: AVOID apprehension position (flexion>90, horiz abd>90, ER to 80)
Diagnostic tests: plain film, CT scan, MRI
Meds: acetaminophen, NSAIDs
PT GOALS:
joint mobs
exercise focused on regaining scapulothoracic, GH stabilization and muscular re-ed
Instability (Shoulder)
Traumatic: young throwing athletes
Atraumatic: congenitally loose connective tissue around shoulder
Popping/clicking and repeated dislocation/subluxation of shoulder
Unstable injuries require surgery
Meds: acetaminophen, NSAIDs
PT GOALS:
return of function without pain
POST SURGERY:
Sling 3-4 wks
After 6 wks: sports-specific training
Full fitness: 3-4 months
Labral Tears
Superior: toward the top of glenoid socket
Inferior: toward bottom of glenoid socket
SLAP: tear of rim above middle of socket that may also involve biceps tendon
Bankart’s lesion: tear of rim below middle of glenoid socket
S/S: Pain cannot be localized Pn incr with OH activities or arm behind back Weakness Instability Pn on resisted flexion of biceps Tenderness over front of shoulder
Diagnostic tests: MRI arthrogram, “gold” standard: arthroscopic surgery
Meds: acetaminophen, NSAIDs
POST SURGERY:
Sling 3-4 wks
After 6 wks: sports-specific training
Full fitness: 3-4 months
Thoracic Outlet Syndrome (TOS)
Compression of neuromuscular bundle (brachial plexus, subclavian A/V, vagus and phrenic nerves and sympathetic trunk)
Common areas of compression: Superior thoracic outlet Scalene triangle Between clavicle and first rib Between p. minor and thoracic wall
Surgery: remove cervical rib or release anterior and/or middle scalene
Diagnostic tests: plain film, MRI, EMG
Special tests: Adson’s, Roo’s, Wright, Costoclavicular
Meds: acetaminophen, NSAIDs
PT GOALS:
Postural re-ed
Manipulations (first rib)