Multiple Sclerosis

Question 1

What is Multiple Sclerosis?

Answer 1

A chronic autoimmune disease that affects the central nervous system.

Question 2

What is the primary action of interferon beta medications?

Answer 2

To modulate the immune response and reduce inflammation.

Question 3

True or False: Glatiramer acetate is a first-line treatment for MS.

Answer 3

True

Question 4

List one common adverse effect of interferon beta.

Answer 4

Flu-like symptoms.

Question 5

What is the generic name of Copaxone?

Answer 5

Glatiramer acetate.

Question 6

What type of drug is natalizumab?

Answer 6

A monoclonal antibody.

Question 7

Fill in the blank: The drug _______ can increase the risk of progressive multifocal leukoencephalopathy (PML).

Answer 7

Natalizumab.

Question 8

Which medication is contraindicated in patients with liver disease?

Answer 8

Teriflunomide.

Question 9

What is the mechanism of action of dimethyl fumarate?

Answer 9

It activates the Nrf2 pathway, providing neuroprotection.

Question 10

Which MS drug is taken orally?

Answer 10

Dimethyl fumarate.

Question 11

True or False: The use of corticosteroids is a common treatment for acute MS relapses.

Answer 11

True

Question 12

What is one major side effect of teriflunomide?

Answer 12

Hepatotoxicity.

Question 13

What is the generic name for Aubagio?

Answer 13

Teriflunomide.

Question 14

Which MS treatment is associated with injection site reactions?

Answer 14

Interferon beta.

Question 15

Name a drug interaction concern with fingolimod.

Answer 15

Bradycardia with certain heart medications.

Question 16

What is the action of ocrelizumab?

Answer 16

It depletes CD20-positive B cells.

Question 17

Fill in the blank: _______ is a medication used for primary progressive MS.

Answer 17

Ocrelizumab.

Question 18

True or False: MS is more common in women than in men.

Answer 18

True

Question 19

What is the primary goal of MS pharmacotherapy?

Answer 19

To manage symptoms and reduce the frequency of relapses.

Question 20

What is one common side effect of dimethyl fumarate?

Answer 20

Gastrointestinal upset.

Question 21

What type of drug is cladribine?

Answer 21

An alkylating agent.

Question 22

Which medication requires monitoring for lymphocyte count?

Answer 22

Fingolimod.

Question 23

What is the mechanism of action of alemtuzumab?

Answer 23

It targets CD52 on lymphocytes, leading to their depletion.

Question 24

Fill in the blank: _______ is used for treating relapsing forms of MS.

Answer 24

Alemtuzumab.

Question 25

What is a potential long-term side effect of alemtuzumab?

Answer 25

Autoimmune disorders.

Question 26

True or False: All MS medications are safe during pregnancy.

Answer 26

False

Question 27

What is the main symptom of MS?

Answer 27

Varied; can include fatigue, weakness, and sensory disturbances.

Question 28

What is the generic name of Gilenya?

Answer 28

Fingolimod.

Question 29

Which MS medication is administered via infusion?

Answer 29

Alemtuzumab.

Question 30

What is the effect of MS on the myelin sheath?

Answer 30

It causes demyelination.

Question 31

Fill in the blank: _______ is a common symptom of MS that affects mobility.

Answer 31

Spasticity.

Question 32

What is one contraindication for using ocrelizumab?

Answer 32

Active hepatitis B infection.

Question 33

What is the role of corticosteroids in MS treatment?

Answer 33

To reduce inflammation during relapses.

Question 34

What is the mechanism of action of teriflunomide?

Answer 34

It inhibits pyrimidine synthesis, reducing lymphocyte proliferation.

Question 35

True or False: MS can lead to cognitive impairment.

Answer 35

True

Question 36

What is a common laboratory test to monitor in MS patients on immunosuppressants?

Answer 36

Complete blood count (CBC).

Question 37

What is the role of lifestyle changes in managing MS?

Answer 37

To improve overall health and manage symptoms.

Question 38

What type of MS is characterized by a steady progression of symptoms?

Answer 38

Primary progressive MS.

Question 39

Fill in the blank: _______ is the term for periods of new or increasing neurologic symptoms in MS.

Answer 39

Relapse.

Question 40

What is one advantage of using oral MS medications?

Answer 40

Ease of administration.

Question 41

What is the recommended approach for managing acute exacerbations of MS?

Answer 41

Administer high-dose corticosteroids.

Question 42

What is a common side effect of glatiramer acetate?

Answer 42

Injection site pain.

Question 43

What is the importance of patient education in MS management?

Answer 43

To ensure adherence to treatment and understanding of the disease.

Question 44

What is the action of sphingosine 1-phosphate receptor modulators?

Answer 44

They prevent lymphocytes from leaving lymph nodes.

Question 45

What is a potential risk of long-term immunosuppressive therapy in MS?

Answer 45

Increased risk of infections.