Multiple Sclerosis- MS Flashcards Preview

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Flashcards in Multiple Sclerosis- MS Deck (16):
1

Typical location for MS lesions:

1. CC
2. U fibers- juxtacortical
3. TL
4. Brainstem
5. Cerebellum
6. Spinal cord

2

Which sequence is best to look at spinal cord lesions in MS?

PD

3

What are the Dawson's fingers?

Ovoid lesions perpendicular to ventricles.

4

Whats the lesion?
mass lesion with incomplete ring enhancement on post contrast images

Tumefactive MS

Intraparenchymal lesion

5

Ddx bwn glioma and demyelination?

Glioma: closed ring enhancement
Demyelination: Open ring

6

What is the lesion?
alternating bands of demyelination and myelin preservation in whorl like configuration:

balo Concentric sclerosis

7

What is the lesion?
This is a demyelinating disease in which the optic nerves and spinal cord are usually involved.
Often there are few T2-lesions in the brain.

Neuromyelitis optica

8

This drug increases the risk of PML:

Natalizumab- used in treatment of MS

9

جملات كليدي




دکتر احمد حلت:
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❌➕
@drahmadhelat

10

Findings in NMO

T2 lesions in the brain
Spinal cord lesions with low T1 and swelling of the cord

11

What is the lesion?

This is a monophonic immune mediated demyelinating disease usually in children post infection/ vaccination

ADEM - Acute Disseminating Encephalomyelitis

12

Where is usually affected by ADEM?

Cortical grey matter and deep grey matter of the BG and thalami.

13

Typical findings of ADEM

multifocal lesions in WM and BG 10-14 days post infection or vaccination

14

Typical findings in Lyme disease

2-3 mm lesions simulating MS in a patient with skin rash and influenza like illness.

high signal in spinal cord and enhancement of CN7

15

Key findings in PML

Space occupying non enhancing WML in U fibres- unlike HIV/CMV

Caused by JC virus

16

What is the pathology?

Migraine, dementia and family history

CADASIL